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Results for "

PFAS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Arginase (1) Atg8/LC3 (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (4) Caspase (1) Drug Intermediate (1) ERK (1) Ferroptosis (1) HIV (1) iGluR (2) Interleukin Related (1) mTOR (1) p62 (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Small Interfering RNA (siRNA) (4) TGF-beta/Smad (1) TSH Receptor (2) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (1) Infection (5) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (4)

Inhibitors & Agonists

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W269593

Perfluorodecanoic acid 1 Publications Verification PFDA	Caspase Interleukin Related	Metabolic Disease
Perfluorodecanoic acid (PFDA) is a perfluoroalkyl substance (PFAS). Perfluorodecanoic acid induces weight loss and increases liver weight and lipid content in mice. Perfluorodecanoic acid also reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver .

HY-W002199

6:2 Fluorotelomer alcohol 6:2 FTOH; 1H,1H,2H,2H-Perfluoro-1-octanol; 2-(Perfluorohexyl)ethanol	Bacterial	Infection
6:2 Fluorotelomer alcohol (6:2 FTOH) is a short-chain perfluoroalkyl substance (PFAS) in polymer PFAS that can be degraded by microbial action, significantly affecting the structure of bacterial communities in sediments and causing changes in the richness and diversity of the bacterial communities .

HY-W792491

Perfluoropropanesulfonic acid	Others	Others
Perfluoropropanesulfonic acid (PFPrS) is a chemical compound that belongs to the group of perfluoroalkyl substances (PFAS) .

HY-RS19931

Pfas Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pfas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pfas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pfas Mouse Pre-designed siRNA Set A Pfas Mouse Pre-designed siRNA Set A

HY-RS10357

PFAS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PFAS Human Pre-designed siRNA Set A contains three designed siRNAs for PFAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PFAS Human Pre-designed siRNA Set A PFAS Human Pre-designed siRNA Set A

HY-RS26433

Pfas Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pfas Rat Pre-designed siRNA Set A contains three designed siRNAs for Pfas gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pfas Rat Pre-designed siRNA Set A Pfas Rat Pre-designed siRNA Set A

HY-W275295

Perfluorododecanoic acid PFDoA	Reactive Oxygen Species (ROS)	Metabolic Disease
Perfluorododecanoic acid (PFDoA) is a perfluoroalkyl substance (PFAS) found in lake trout. Perfluorododecanoic acid decreases the viability of PC12 cells. Perfluorododecanoic acid also increases reactive oxygen species (ROS), malondialdehyde (MDA) levels and reduces the mitochondrial membrane potential in PC12 cells .

HY-RS28695

Fnta Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fnta Rat Pre-designed siRNA Set A contains three designed siRNAs for Fnta gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fnta Rat Pre-designed siRNA Set A Fnta Rat Pre-designed siRNA Set A

HY-169848

(S)-Batylalcohol 1-O-Octadecyl-sn-glycerol	HIV	Infection
(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is a phosphonoformic acid (PFA) analog that exhibits higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) than PFA. (S)-Batylalcohol can be used in antiretroviral research .

HY-W591838

Perfluoropentanesulfonic acid PFPeS	Biochemical Assay Reagents	Others
Perfluoropentanesulfonic acid (PFPeS) is a per- and polyfluoroalkyl substance, which can be found as contaminant in wastewater .

HY-W674169

Perfluorobutanesulfonamide FBSA	Biochemical Assay Reagents	Others
Perfluorobutanesulfonamide (FBSA) is a per- and polyfluoroalkyl substance, which can be found as contaminant in wastewater .

HY-W679758

1H,1H,2H,2H-Perfluorodecanesulfonic acid	Drug Intermediate	Others
1H,1H,2H,2H-Perfluorodecanesulfonic acid (8:2 FTS) is a polyfluoroalkyl substance (PFAS) precursor .

HY-W080797

4,4,5,5,6,6,6-Heptafluorohexanoic acid 3:3 FTCA	Biochemical Assay Reagents	Others
4,4,5,5,6,6,6-Heptafluorohexanoic acid (3:3 FTCA) is a polyfluoroalkyl substance (PFAS) that accumulate in the environment. 3:3 FTCA binds to many proteins, including the primary human serum transport protein albumin (HSA) .

HY-21200

Perfluoroheptanesulfonic acid 1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid; PFHpS	iGluR	Infection
Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). PFHpS can induce malformations in zebrafish larvae (EC₅₀=168.1 μM). It has also been found in landfill leachate, and fetal exposure to PFHpS can lead to reduced birth weight.

HY-21197

Perfluoroenanthic acid Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA	iGluR	Neurological Disease
Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95 .

HY-W679754

Pentacosafluorotridecanoic Acid PFTrDA	TSH Receptor	Infection
Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.

HY-W142432

Perfluoroundecanoic acid	Biochemical Assay Reagents β-catenin Wnt Arginase TGF-beta/Smad mTOR Akt ERK Atg8/LC3 p62 Autophagy	Metabolic Disease Inflammation/Immunology Cancer
Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS). Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation .

HY-W679754R

Pentacosafluorotridecanoic Acid (Standard) PFTrDA (Standard)	TSH Receptor Reference Standards	Infection
Pentacosafluorotridecanoic Acid (Standard) is the analytical standard of Pentacosafluorotridecanoic Acid. This product is intended for research and analytical applications. Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.

HY-115701

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE	Ferroptosis	Inflammation/Immunology
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.

Pfas Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Pfas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pfas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

PFAS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PFAS Human Pre-designed siRNA Set A contains three designed siRNAs for PFAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pfas Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Pfas Rat Pre-designed siRNA Set A contains three designed siRNAs for Pfas gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fnta Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Fnta Rat Pre-designed siRNA Set A contains three designed siRNAs for Fnta gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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