Perfluorobutanesulfonamide (Synonyms: FBSA)

Cat. No.: HY-W674169: Data Sheet
SDS
Handling Instructions
FAQs
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Perfluorobutanesulfonamide (FBSA) is a per- and polyfluoroalkyl substance, which can be found as contaminant in wastewater.

For research use only. We do not sell to patients.

Perfluorobutanesulfonamide Chemical Structure

CAS No. : 30334-69-1

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Description

Perfluorobutanesulfonamide (FBSA) is a per- and polyfluoroalkyl substance, which can be found as contaminant in wastewater^[1].

Molecular Weight

299.11

Synonyms

FBSA

Formula

C₄H₂F₉NO₂S

CAS No.

30334-69-1

Appearance

Solid

SMILES

O=S(N)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (334.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3433 mL	16.7163 mL	33.4325 mL
5 mM	0.6687 mL	3.3433 mL	6.6865 mL
10 mM	0.3343 mL	1.6716 mL	3.3433 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (16.72 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (16.72 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 5 mg/mL (16.72 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Data Sheet (272 KB) SDS (252 KB) Handling Instructions (2659 KB)

References

[1]. Chen YJ, et al., Emerging Perfluorobutane Sulfonamido Derivatives as a New Trend of Surfactants Used in the Semiconductor Industry. Environ Sci Technol. 2024 Jan 23;58(3):1648-1658. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3433 mL	16.7163 mL	33.4325 mL	83.5813 mL
	5 mM	0.6687 mL	3.3433 mL	6.6865 mL	16.7163 mL
	10 mM	0.3343 mL	1.6716 mL	3.3433 mL	8.3581 mL
	15 mM	0.2229 mL	1.1144 mL	2.2288 mL	5.5721 mL
	20 mM	0.1672 mL	0.8358 mL	1.6716 mL	4.1791 mL
	25 mM	0.1337 mL	0.6687 mL	1.3373 mL	3.3433 mL
	30 mM	0.1114 mL	0.5572 mL	1.1144 mL	2.7860 mL
	40 mM	0.0836 mL	0.4179 mL	0.8358 mL	2.0895 mL
	50 mM	0.0669 mL	0.3343 mL	0.6687 mL	1.6716 mL
	60 mM	0.0557 mL	0.2786 mL	0.5572 mL	1.3930 mL
	80 mM	0.0418 mL	0.2090 mL	0.4179 mL	1.0448 mL
	100 mM	0.0334 mL	0.1672 mL	0.3343 mL	0.8358 mL

Perfluorobutanesulfonamide Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perfluorobutanesulfonamide30334-69-1FBSABiochemical Assay ReagentsPFASwastewaterInhibitorinhibitorinhibit

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Perfluorobutanesulfonamide (Synonyms: FBSA)

Perfluorobutanesulfonamide Related Antibodies

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