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Results for "

PDIA1

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Recombinant Proteins

3

Antibodies

3

Click Chemistry

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117570
    KSC-34

    		PDI Neurological Disease
    KSC-34, a covalent modifier of protein disulfide isomerase A1 (PDIA1), is also a selective and potent a-site inhibitor of PDIA1 with an IC50 of 3.5 μM. KSC-34 displays a 30-fold selectivity for a domain over a′ domain and displays high selectivity for PDIA1 in complex proteomes with minimal engagement of other members of the PDI family [1]. KSC-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    KSC-34
  • HY-122895
    E64FC26
    2 Publications Verification

    		 Apoptosis PDI Cancer
    E64FC26 is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6, respectively. E64FC26 shows anti-myeloma activity [1].
    E64FC26
  • HY-122895A
    (E/Z)-E64FC26

    		Apoptosis PDI Cancer
    (E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity [1] .
    (E/Z)-E64FC26
  • HY-175484
    PDIA1-IN-1

    		PDI Interleukin Related Neurological Disease Inflammation/Immunology
    PDIA1-IN-1 is a protein disulfide isomerase 1 (PDIA1) inhibitor. PDIA1-IN-1 can inhibit NLRP3 inflammasome assembly and activity, with an IC50 value of 1 μM. PDIA1-IN-1 can reduce IL-1β secretion. PDIA1-IN-1 can be used for the researches of inflammation and neurological disease [1].
    PDIA1-IN-1
  • HY-178118
    PROTAC PDIA1 degrader 1

    		PROTACs PDI Cancer
    PROTAC PDIA1 degrader 1 (Compound H4) is a PDIA1 PROTAC degrader with a DC50 of 29.71 μM. PROTAC PDIA1 degrader 1 has potent anticancer activity and significantly inhibits cancer cell proliferation [1]. Pink: PDIA1 ligand (HY-100433); Blue: CRBN ligase ligand (HY-10984); Black: linker (HY-W015088)
    PROTAC PDIA1 degrader 1
  • HY-RS18780
    P4hb Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    P4hb Mouse Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    P4hb Mouse Pre-designed siRNA Set A
    P4hb Mouse Pre-designed siRNA Set A
  • HY-RS09945
    P4HB Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    P4HB Human Pre-designed siRNA Set A contains three designed siRNAs for P4HB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    P4HB Human Pre-designed siRNA Set A
    P4HB Human Pre-designed siRNA Set A

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