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Results for "

OCT-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adrenergic Receptor (2) Autophagy (2) Bacterial (3) Dopamine Receptor (4) Drug Metabolite (1) Isotope-Labeled Compounds (2) Monoamine Transporter (1) OAT (2) Reference Standards (4) Serotonin Transporter (1) Small Interfering RNA (siRNA) (4) Tyrosine Hydroxylase (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Endocrinology (2) Infection (3) Metabolic Disease (6) Neurological Disease (5)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Oct3/4

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010410

Oct-1-en-3-ol	Others	Neurological Disease Metabolic Disease
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling ^[1] .

HY-N0750

Monocrotaline Maximum Cited Publications 37 Publications Verification Crotaline	Others	Metabolic Disease Cancer
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits *OCT-1* and *OCT-2* with IC₅₀s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. ^[2][6][8].

HY-B0193A

Prazosin hydrochloride 10+ Cited Publications	Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders ^[1]. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC₅₀ of 0.15 nM .Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC₅₀s of 1.8, and 13 μM, respectively .

HY-N2003

D-Tetrahydropalmatine 1 Publications Verification	Dopamine Receptor	Metabolic Disease
D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis ^[1]. D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors . D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor .

HY-107740

Pseudoisocyanine iodide 1,1'-Diethyl-2,2'-cyanine iodide; Decynium 22; Diethylcyanine iodide; Eastman 7851	Monoamine Transporter Serotonin Transporter	Neurological Disease
Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, *OCT2, OCT3) and plasma membrane monoamine transporter (PMAT*). Pseudoisocyanine iodide has antidepressant activity ^[1] .

HY-W010410S

Oct-1-en-3-ol-d3	Isotope-Labeled Compounds	Metabolic Disease
Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities ^[1] .

HY-W010410R

Oct-1-en-3-ol (Standard)	Reference Standards Others	Neurological Disease Metabolic Disease
Methyl ricinoleate (Standard) is the analytical standard of Methyl ricinoleate. This product is intended for research and analytical applications. Methyl ricinoleate is a compound belonging to the group of fatty acid methyl esters. It is derived from ricinoleic acid, a monounsaturated omega-9 fatty acid found in castor oil. Methyl ricinoleate is often used as a reference compound for the analysis of fatty acid methyl esters by gas chromatography. It has also been investigated for its potential use as a biofuel and as an ingredient in the production of biodegradable plastics and surfactants.

HY-N0750R

Monocrotaline (Standard) Crotaline (Standard)	Others	Metabolic Disease Cancer
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits OCT-1 and OCT-2 with IC50s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. .

HY-B0193AR

Prazosin hydrochloride (Standard)	Reference Standards Adrenergic Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Prazosin (hydrochloride) (Standard) is the analytical standard of Prazosin (hydrochloride). This product is intended for research and analytical applications. Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders ^[1]. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC₅₀ of 0.15 nM .Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC₅₀s of 1.8, and 13 μM, respectively .

HY-W781133

cDPCP cis-[Pt(NH3)2(N1-pyridine)Cl]Cl	Others	Cancer
cDPCP (cis-[Pt(NH3)2(N1-pyridine)Cl]Cl) is a DNA crosslinking agent and also a substrate for *OCT1* and *OCT2*. DPCP exhibits anticancer activity and can improve the survival rate of sarcoma-180 mice. cDPCP is suitable for the research of colorectal cancer and cancers with appropriate cation transporters ^[1] .

HY-B0306

Prothionamide Protionamide	Bacterial	Infection
Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy ^[1] .

HY-B0306S

Prothionamide-d5 Protionamide-d₅	Isotope-Labeled Compounds Bacterial	Infection
Prothionamide-d₅ is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy ^[1] .

HY-B0306R

Prothionamide (Standard) Protionamide (Standard)	Reference Standards Bacterial	Infection
Prothionamide (Standard) is the analytical standard of Prothionamide (HY-B0306). This product is intended for research and analytical applications. Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy ^[1] .

HY-B0927

Hydrastine (-)-β-Hydrastine; (1R,9S)-β-Hydrastine	Tyrosine Hydroxylase Dopamine Receptor OAT	Neurological Disease
Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage ^[1] .

HY-100057

BMY 28674 6-Hydroxybuspirone; 6'-Hydroxybuspirone; BMS 528215	5-HT Receptor Drug Metabolite Dopamine Receptor	Neurological Disease
BMY 28674 (6-Hydroxybuspirone) is the active metabolite of the anxiolytic buspirone (HY-B1115A) and is metabolized by CYP3A4.4. BMY 28674 binds to the serotonin (5-HT) receptor subtype *5-HT1A* in the rat hippocampus and dorsal raphe (EC₅₀s are 4 and 1 μM, respectively) and is an antagonist of dopamine D2, D3, and D4 receptors (IC₅₀s are 3.1, 4.9, and 0.85 μM, respectively). BMY 28674 also inhibits organic cation transporter 1 (OCT1), OCT2, and OCT3 expressing human transporters in S2 proximal tubule cells in a concentration-dependent manner.

HY-B0927R

Hydrastine (Standard) (-)-β-Hydrastine (Standard); (1R,9S)-β-Hydrastine (Standard)	Reference Standards Tyrosine Hydroxylase Dopamine Receptor OAT	Others
Hydrastine (Standard) is the analytical standard of Hydrastine (HY-B0927). This product is intended for research and analytical applications. Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage ^[1] .

HY-RS13061

SLC22A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC22A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC22A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC22A1 Human Pre-designed siRNA Set A SLC22A1 Human Pre-designed siRNA Set A

HY-RS26339

Slc22a1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Slc22a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc22a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc22a1 Rat Pre-designed siRNA Set A Slc22a1 Rat Pre-designed siRNA Set A

HY-RS19841

Slc22a1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Slc22a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc22a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc22a1 Mouse Pre-designed siRNA Set A Slc22a1 Mouse Pre-designed siRNA Set A

HY-RS10897

POU2F1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
POU2F1 Human Pre-designed siRNA Set A contains three designed siRNAs for POU2F1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

POU2F1 Human Pre-designed siRNA Set A POU2F1 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010410

Oct-1-en-3-ol	Microorganisms Source classification Plants	Others
Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling ^[1] .

HY-N0750

Monocrotaline 35+ Cited Publications Crotaline	Structural Classification Alkaloids Pyrrole Alkaloids Classification of Application Fields Leguminosae Crotalaria pallida Ait. Plants Disease Research Fields Cancer	Others
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits *OCT-1* and *OCT-2* with IC₅₀s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. ^[2][6][8].

HY-N2003

D-Tetrahydropalmatine 1 Publications Verification	Alkaloids Structural Classification Corydalis yanhusuo W. T. Wang Classification of Application Fields Source classification Metabolic Disease Plants Isoquinoline Alkaloids Disease Research Fields Papaveraceae	Dopamine Receptor
D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis ^[1]. D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors . D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor .

HY-B0927

Hydrastine (-)-β-Hydrastine; (1R,9S)-β-Hydrastine	Structural Classification Alkaloids Piperidine Alkaloids Classification of Application Fields Ranunculaceae Other Diseases Plants Disease Research Fields	Tyrosine Hydroxylase Dopamine Receptor OAT
Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage ^[1] .

HY-W010410R

Oct-1-en-3-ol (Standard)	Microorganisms Source classification Plants	Reference Standards Others
Methyl ricinoleate (Standard) is the analytical standard of Methyl ricinoleate. This product is intended for research and analytical applications. Methyl ricinoleate is a compound belonging to the group of fatty acid methyl esters. It is derived from ricinoleic acid, a monounsaturated omega-9 fatty acid found in castor oil. Methyl ricinoleate is often used as a reference compound for the analysis of fatty acid methyl esters by gas chromatography. It has also been investigated for its potential use as a biofuel and as an ingredient in the production of biodegradable plastics and surfactants.

HY-N0750R

Monocrotaline (Standard) Crotaline (Standard)	Structural Classification Alkaloids Pyrrole Alkaloids Leguminosae Crotalaria pallida Ait. Plants	Others
Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits OCT-1 and OCT-2 with IC50s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. .

HY-B0927R

Hydrastine (Standard) (-)-β-Hydrastine (Standard); (1R,9S)-β-Hydrastine (Standard)	Structural Classification Alkaloids Piperidine Alkaloids Ranunculaceae Plants	Reference Standards Tyrosine Hydroxylase Dopamine Receptor OAT
Hydrastine (Standard) is the analytical standard of Hydrastine (HY-B0927). This product is intended for research and analytical applications. Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage ^[1] .

Cat. No.	Compare	Product Name	Species	Source

HY-P72201

	GAPDH Protein, Human (His-SUMO) G3P_HUMAN; G3PD; G3PDH; GAPD; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; glyceraldehyde 3-PDH; Glyceraldehyde-3-phosphate dehydrogenase; HEL-S-162eP; KNC-NDS6; MGC102544; OCAS; p38 component; OCT1 coactivator in S phase; 38-KD component; peptidyl cysteine S nitrosylase GAPDH	Human	E. coli
	GAPDH, a multifunctional protein, acts as a key enzyme in glycolysis, catalyzing the conversion of G3P. It also functions as a nitrosylase, impacting nuclear processes. In addition, it influences cytoskeleton organization, associates with CHP1, participates in transcript-selective translation inhibition, contributes to immune responses, and mediates nuclear events through S-nitrosylation of target proteins. GAPDH Protein, Human (His-SUMO) is the recombinant human-derived GAPDH protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W010410S

Oct-1-en-3-ol-d3
Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities ^[1] .

Oct-1-en-3-ol-d3

Oct-1-en-3-ol-d₃ is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities ^[1] .

HY-B0306S

Prothionamide-d5
Prothionamide-d₅ is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of *OCT1* with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy ^[1] .

Prothionamide-d5

Prothionamide-d₅ is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a K_m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy ^[1] .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P87293

	Oct-1 Antibody (YA6976) FLJ42836 antibody; NF A1 antibody; NF-A1 antibody; OCT 1 antibody; OCT 1B antibody; OCT-1 antibody; OCT1 antibody; OCTamer binding protein 1 antibody; OCTamer binding transcription factor 1 antibody; OCTamer-binding protein 1 antibody	WB, IHC-P, IHC-F, IF-Tissue, FC, ICC/IF	Human, Mouse, Rat
	Oct-1 Antibody (YA6976) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Oct-1.

HY-P85672

	OCT1 Antibody (YA5364)	WB, IHC-P, ICC/IF,	Human
	OCT1 Antibody (YA5364) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to OCT1.

HY-P83828

	*SLC22A1/OCT1* Antibody (YA3525)** OCT1; HOCT1; OCT1_cds; SLC22A1	FC, ELISA	Human
	SLC22A1/OCT1 Antibody (YA3525) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC22A1/OCT1.

HY-P82681

	*SLC22A1/OCT1* Antibody (YA2426)** hOCT1; OCT1; Slc22a1	WB, FC	Human
	SLC22A1/OCT1 Antibody (YA2426) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC22A1/OCT1.

HY-P85303

	*SLC22A1/OCT1* Antibody (YA4995)** SLC22A1; OCT1; Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1	WB, FC, ELISA	Human
	SLC22A1/OCT1 Antibody (YA4995) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SLC22A1/OCT1.

HY-P85379

	SYK Antibody (YA5071) SLC22A1; OCT1; Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1	WB, ELISA	Human
	SYK Antibody (YA5071) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SYK.