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Native Proteins

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414

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4

Fluorescent Dye

412

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3

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1

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2

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5

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1

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-NP010
    Collagen, rat tail

    		MMP Others
    Collagen, rat tail is a kind of collagen extracted from rat tail tendon tissue. Collagen, rat tail stimulates cell growth. Collagen, rat tail is often used as an attachment substrate for cell culture .
    Collagen, rat tail
  • HY-NP001
    Cationic Bovine Serum Albumin
    1 Publications Verification

    CBSA

    		 Biochemical Assay Reagents Neurological Disease
    Cationic Bovine Serum Albumin is a bovine serum albumin (BSA) modified with excess ethylenediamine, which has enhanced immunogenicity compared to native BSA. Positively charged primary amines block all negatively charged carboxyl groups, making Cationic Bovine Serum Albumin a cationic protein. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
    Cationic Bovine Serum Albumin
  • HY-NP020
    E.coli DH-5 alpha Bacterial protein

    E.coli DH-5 alpha protein

    		 Bacterial Others
    E.coli DH-5 alpha Bacterial protein is a purified native protein from E.coli DH-5 alpha bacterial .
    E.coli DH-5 alpha Bacterial protein
  • HY-NP025
    E.coli Bacterial protein

    EPEC

    		 Bacterial Infection
    E.coli Bacterial protein is a native protein that can be isolated from E.coli .
    E.coli Bacterial protein
  • HY-NP016
    Brucella bacterial protein

    		Bacterial Biochemical Assay Reagents Others
    Brucella bacterial protein is native protein that purified from Brucella for life science related research .
    Brucella bacterial protein
  • HY-158882
    FLAC6

    		Biochemical Assay Reagents Adenosine Receptor Others
    FLAC6 is a potent fluorinated detergent that can be used to solubilize membrane proteins (the native adenosine receptor A2AR, a G protein-coupled receptor, and two native transporters AcrB and BmrA). FLAC6 can maintain the structural and functional integrity of different membrane proteins .
    FLAC6
  • HY-P5428
    Cdc2 kinase substrate

    		CDK Others
    Cdc2 kinase substrate is a biological active peptide. (The native peptide HATPPKKKRK is a substrate for cyclin-dependent protein kinase 1 (CDC2; CDK1).)
    Cdc2 kinase substrate
  • HY-D0167
    NHS-5(6)Carboxyrhodamine

    		Fluorescent Dye Others
    NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
    NHS-5(6)Carboxyrhodamine
  • HY-W615327
    Bis-sulfone NHS ester

    		Biochemical Assay Reagents Others
    Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.
    Bis-sulfone NHS ester
  • HY-W190952
    Bis-sulfone-PEG4-NHS ester

    		Biochemical Assay Reagents Others
    Bis-sulfone-PEG4-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
    Bis-sulfone-PEG4-NHS ester
  • HY-W800627
    Bis-sulfone-PEG8-NHS ester

    		Biochemical Assay Reagents Others
    Bis-sulfone-PEG8-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
    Bis-sulfone-PEG8-NHS ester
  • HY-NP008
    β-Lactoglobulin

    		Lipocalin Family Inflammation/Immunology
    β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products .
    β-Lactoglobulin
  • HY-P99930
    Efruxifermin
    2 Publications Verification

    AKR-001; AMG-876

    		 FGFR Metabolic Disease
    Efruxifermin is an Fc-FGF21 fusion protein (human IgG1 Fc domain linked to a modified human FGF21). Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis .
    Efruxifermin
  • HY-112641
    AkaLumine

    		Fluorescent Dye Cancer
    AkaLumine is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
    AkaLumine
  • HY-112641A
    AkaLumine hydrochloride
    4 Publications Verification

    		 Fluorescent Dye Cancer
    AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
    AkaLumine hydrochloride
  • HY-112096
    eCF506
    4 Publications Verification

    NXP900

    		 Src Cancer
    eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer .
    eCF506
  • HY-N10264
    Avrainvillamide

    (+)-Avrainvillamide; CJ-17,665

    		 Antibiotic Infection Cancer
    Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .
    Avrainvillamide
  • HY-P991677
    Efmirenpase alfa

    		Phosphodiesterase (PDE) Cardiovascular Disease Endocrinology
    Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research .
    Efmirenpase alfa
  • HY-W414390
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%

    2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%

    		 Biochemical Assay Reagents Others
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98% (2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%) is a detergent that can be used for the purification and crystallization of membrane-bound proteins in their native structure. It can self-assemble into micelles and vesicles in aqueous solution and can be used for the study of biomembrane models.
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%
  • HY-42984
    BHQ-2 NHS

    		Biochemical Assay Reagents Others
    BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    BHQ-2 NHS
  • HY-E70565
    O-Glycoprotease

    		Endonuclease Inflammation/Immunology
    O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6×His tag at the C-terminus.
    The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn 2+.
    O-Glycoprotease
  • HY-W1005067
    EN171

    		Molecular Glues Hippo (MST) Estrogen Receptor/ERR Others
    EN171 is a covalent ligand that covalently targets both C38 and C96 on 14-3-3 to enhance 14-3-3 interactions with ERα, YAP and TAZ, leading to impaired estrogen receptor and Hippo pathway transcriptional activity. EN171 can not only be used as a molecular glue to enhance native protein interactions but can also be used as a covalent 14-3-3 recruiter in heterobifunctional molecules to sequester nuclear neo-substrates such as BRD4 and BLC6 into the cytosol .
    EN171
  • HY-112096S
    eCF506-d5

    NXP900-d5

    		 Src Isotope-Labeled Compounds Cancer
    eCF506-d5 (NXP900-d5) is deuterated labeled eCF506 (HY-112096). eCF506 is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer .
    eCF506-d5
  • HY-116748
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

    		PDI Phosphatase
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane is a small-molecule dithiol catalyst with a low thiol pKa value (8.3) and high reduction potential (-0.24 V), capable of mimicking PDI activity. It catalyzes the activation of scrambled ribonuclease A (scrambled ribonuclease A) and promotes the formation of native disulfide bonds, thereby significantly enhancing protein folding efficiency. Adding (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane to the culture medium of Saccharomyces cerevisiae can increase the secretion of exogenously expressed Schizosaccharomyces pombe acid phosphatase by more than threefold. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane holds great potential for applications in protein production and secretion research .
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
  • HY-NP0158
    Ulex Europaeus Agglutinin I (Rhodamine)

    UEA I (Rhodamine)

    		 Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Rhodamine)
  • HY-NP201
    Human immunoglobulin E

    Human IgE

    		 Biochemical Assay Reagents Inflammation/Immunology
    Human immunoglobulin E (Human IgE) is a key mediator in allergic diseases. Human immunoglobulin E is made up of heavy (H) and light (L) chains, of which the variable (V) domains of the H chains are believed to contribute much to their antigenbinding properties .
    Human immunoglobulin E
  • HY-NP002H
    Porcine Serum Albumin (globulin free)

    		Biochemical Assay Reagents Others
    Porcine Serum Albumin (globulin free) is a serum albumin protein that contains a flexible C-terminal region.
    Porcine Serum Albumin (globulin free)
  • HY-NP156
    Type I Collagen, for cell culture, from Bovine

    		Biochemical Assay Reagents Others
    Type I Collagen, for cell culture, from Bovine plays an important role in the structure and function of skin, bones, tendons, etc. Type I Collagen, for cell culture, from Bovine can mimic the extracellular matrix (ECM) and is suitable for 2D/3D cell culture .
    Type I Collagen, for cell culture, from Bovine
  • HY-NP083A
    Wisteria Floribunda Lectin (Biotin)

    WFA (Biotin)

    		 Biochemical Assay Reagents Inflammation/Immunology
    Wisteria Floribunda Lectin (Biotin) (WFA (Biotin)) is a biotinylated lectin with affinity for N-acetyl-D-galactosamine .
    Wisteria Floribunda Lectin (Biotin)
  • HY-118667
    Dehydroergosterol

    		Liposome Others
    Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .
    Dehydroergosterol
  • HY-107903
    Thyroglobulin

    Thyroglobulin from bovine

    		 Biochemical Assay Reagents Cancer
    Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle .
    Thyroglobulin
  • HY-NP128
    Highly purified Type I collagen, from rabbit skin

    Rabbit Type I collagen, immunization grade

    		 MMP Inflammation/Immunology
    Highly purified Type I collagen, from rabbit skin (Canine Type I collagen, immunization grade) is an immune grade collagen derived from rabbit skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type I collagen, from rabbit skin
  • HY-NP0241C
    Chick CB11 of type II collagen

    Chick Cyanogen bromide digested peptide 11

    		 Biochemical Assay Reagents Inflammation/Immunology
    Chick CB11 of type II collagen (Chick cyanogen bromide digested peptide 11) is a cyanobromide digested peptide (CB-peptide) fragment of type II collagen, which can be used to study B cell and T cell epitopes of type II collagen. This product is pepsin-free, making it ideal for studying T cell epitope specificity through proliferation assays. Chick CB11 of type II collagen can also be used as an antigen for analyzing antibody epitope specificity via ELISA .
    Chick CB11 of type II collagen
  • HY-NP180
    Progesterone/BSA

    		Biochemical Assay Reagents Endocrinology
    Progesterone/BSA is a conjugate of Progesterone (HY-N0437) and bovine serum albumin. Progesterone/BSA has important applications in immunology, diagnostic reagent development and biomedical research .
    Progesterone/BSA
  • HY-NP0243A
    Mouse CB10 of type II collagen

    Mouse cyanogen bromide digested peptide 10

    		 Biochemical Assay Reagents Inflammation/Immunology
    Mouse CB10 of type II collagen (Mouse cyanogen bromide digested peptide 10) is a cyanobromide digested peptide (CB-peptide) fragment of type II collagen, which can be used to study B cell and T cell epitopes of type II collagen. This product is pepsin-free, making it ideal for studying T cell epitope specificity through proliferation assays. Mouse CB10 of type II collagen can also be used as an antigen for analyzing antibody epitope specificity via ELISA .
    Mouse CB10 of type II collagen
  • HY-NP043
    Avidin-Cy3

    		Fluorescent Dye Others
    Avidin-Cy3 is Cy3-labeled Avidin. Avidin has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues .
    Avidin-Cy3
  • HY-NP132
    Recombinant Humanized Type III Collagen 28.6kDa

    		Biochemical Assay Reagents Integrin Cancer
    Recombinant Humanized Type III Collagen 28.6kDa is a type III collagen 28.6kDa. Recombinant humanized type III collagen (rhCOLIII) has various biological functions, such as promoting skin extracellular matrix regeneration and improving the cell microenvironment. rhCOLIII inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen functions in cell adhesion, migration, proliferation and differentiation through its interaction with integrins .
    Recombinant Humanized Type III Collagen 28.6kDa
  • HY-NP0165
    Peanut Agglutinin (Agarose)

    PNA (Agarose)

    		 Fluorescent Dye Others
    Peanut Agglutinin (PNA) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Agarose is a biological material or organic compound that can be used in life science research .
    Peanut Agglutinin (Agarose)
  • HY-125857C
    Cytochrome C (bovine heart)

    		Biochemical Assay Reagents Apoptosis Metabolic Disease
    Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier .
    Cytochrome C (bovine heart)
  • HY-NP163D
    Wheat germ agglutinin-AF594

    WGA-AF594

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF594 (WGA-AF594) is a plant lectin that contains the fluorescent dye AF594, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF594 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF594
  • HY-NP146
    Peanut Agglutinin (CY5)

    		Fluorescent Dye Others
    Peanut Agglutinin CY5 is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.). Peanut Agglutinin CY5 is a biological material or organic compound that can be used in life science research .
    Peanut Agglutinin (CY5)
  • HY-NP158
    Type II Collagen, T Cell Grade, from Bovine

    		Biochemical Assay Reagents Others
    Type II Collagen, T Cell Grade, from Bovine is a T-cell dependent antigen with unique immunological features. Type II Collagen, T Cell Grade, from Bovine can be used as a stimulating antigen for T-cells in in vitro culture systems .
    Type II Collagen, T Cell Grade, from Bovine
  • HY-NP130
    Highly purified Type II collagen, from goat articular cartilage

    Goat Type II collagen, immunization grade

    		 MMP Inflammation/Immunology
    Highly purified Type II collagen, from goat articular cartilage (Goat Type II collagen, immunization grade) is an immune grade collagen derived from goat articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type II collagen, from goat articular cartilage
  • HY-NP164N
    Concanavalin A-Cy3

    Con A-Cy3

    		 Fluorescent Dye Cancer
    Concanavalin A-Cy3 (Con A-Cy3) is a Cy5 (HY-D0822)-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins (Ex/Em = 554/568 nm) .
    Concanavalin A-Cy3
  • HY-NP0217
    Horse Immunoglobulin G

    		Biochemical Assay Reagents Inflammation/Immunology
    Horse Immunoglobulin G is a horse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .
    Horse Immunoglobulin G
  • HY-NP161
    Mussel Adhesive Protein

    MAP

    		 Biochemical Assay Reagents Others
    Mussel Adhesive Protein (MAP) is a natural adhesive that can bind materials ranging from glass, plastics, metals, and wood to materials, such as bone or teeth, biological organisms, and other chemicals or molecules .
    Mussel Adhesive Protein
  • HY-NP185
    Chicken Tenascin,suitable for cell culture

    		Biochemical Assay Reagents Others
    Chicken Tenascin,suitable for cell culture is a glycoprotein that forms disulfide-linked hexamers. Chicken Tenascin,suitable for cell culture is composed of repetitive domains, including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Chicken Tenascin,suitable for cell culture can be used for cell culture .
    Chicken Tenascin,suitable for cell culture
  • HY-NP202
    C2 Protein (human)

    		Complement System Inflammation/Immunology
    C2 Protein (human) is a naturally glycosylated peptide with a 20 amino acid signal sequence. Complement component C2 functions as a key regulator in the early activation phase of the classical pathway and participates in the formation of the classical pathway C3 convertase C4b2a .
    C2 Protein (human)
  • HY-P3160
    Fibronectin
    5+ Cited Publications

    		 Integrin Cardiovascular Disease Inflammation/Immunology
    Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
    Fibronectin
  • HY-NP0243
    Mouse CB8 of type II collagen

    Mouse cyanogen bromide digested peptide 8

    		 Biochemical Assay Reagents Inflammation/Immunology
    Mouse CB8 of type II collagen (Mouse cyanogen bromide digested peptide 8) is a cyanobromide digested peptide (CB-peptide) fragment of type II collagen, which can be used to study B cell and T cell epitopes of type II collagen. This product is pepsin-free, making it ideal for studying T cell epitope specificity through proliferation assays. Mouse CB8 of type II collagen can also be used as an antigen for analyzing antibody epitope specificity via ELISA .
    Mouse CB8 of type II collagen

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