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Results for "

NRG1

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Inhibitory Antibodies

22

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99268
    Seribantumab

    SAR 256212; MM 121; Anti-Human ERBB3/ErbB 3 Recombinant Antibody

    		 EGFR Apoptosis Cancer
    Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models [1].
    Seribantumab
  • HY-RS23046
    Nrg1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Nrg1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nrg1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Nrg1 Rat Pre-designed siRNA Set A
    Nrg1 Rat Pre-designed siRNA Set A
  • HY-RS16611
    Nrg1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Nrg1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nrg1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Nrg1 Mouse Pre-designed siRNA Set A
    Nrg1 Mouse Pre-designed siRNA Set A
  • HY-RS16312
    NRG1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    NRG1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NRG1 Human Pre-designed siRNA Set A
    NRG1 Human Pre-designed siRNA Set A
  • HY-168060
    (8R)-8-Hydroxyepoxyboetirane A

    		PKC Neurological Disease
    (8R)-8-Hydroxyepoxyboetirane A is a neurogenic compound that interacts with PKC δ-C1B. (8R)-8-Hydroxyepoxyboetirane A binds to the PKC enzyme pocket via hydrogen bonds with Gly-253, Leu-251 and Thr242. (8R)-8-Hydroxyepoxyboetirane A induces NRG1 release and differentiation of NSC into neurons. (8R)-8-Hydroxyepoxyboetirane A is promising for research of neurological disorders [1].
    (8R)-8-Hydroxyepoxyboetirane A
  • HY-P991240
    CDX-3379

    		EGFR Cancer
    CDX-3379 is a humanized monoclonal antibody inhibitor targeting ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby inhibiting the phosphorylation of ErbB3. CDX-3379 can inhibit the growth and proliferation of tumor cells. CDX-3379 is promising for research of tumors expressing ErbB3 and NRG1, such as HNSCC [1].
    CDX-3379
  • HY-P991243
    MP-RM-1

    		EGFR PI3K Akt Cancer
    MP-RM-1 is a selective murine monoclonal antibody inhibitor targeting human epidermal growth factor receptor 3 (ErbB-3). MP-RM-1 blocks the activation of ErbB-3 induced by neuregulin 1 (NRG-1β) and promotes the internalization and degradation of ErbB-3, inhibiting downstream signaling pathways such as PI3K-Akt. MP-RM-1 is promising for research of ErbB-3 highly expressed solid tumors such as breast cancer, melanoma, and prostate cancer [1].
    MP-RM-1

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