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NLRP3-IN-79

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174270
    NLRP3-IN-79

    		NOD-like Receptor (NLR) NEKs Inflammation/Immunology
    NLRP3-IN-79 (Compound B6) is a selective NLRP3 inflammasome inhibitor with an IC50 value of 10.69 nM. NLRP3-IN-79 blocks the assembly of the NLRP3 inflammasome by disrupting the NEK7-NLRP3 interaction. NLRP3-IN-79 is promising for research of NLRP3-driven inflammatory diseases such as systemic inflammation, peritonitis, and colitis .
    NLRP3-IN-79

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