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NAPQI-d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Metabolite (1) Endogenous Metabolite (1) Isotope-Labeled Compounds (1)
By Research Areas:	Metabolic Disease (1)

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W744265

NAPQI-d3 N-Acetyl-4-benzoquinone Imine-d<sub>3sub>	Isotope-Labeled Compounds Drug Metabolite Endogenous Metabolite	Metabolic Disease
NAPQI-d₃ (N-Acetyl-4-benzoquinone Imine-d₃) is the deuterium labeled NAPQI (HY-W017464). NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .

Cat. No.	Product Name	Chemical Structure

HY-W744265

NAPQI-d3
NAPQI-d₃ (N-Acetyl-4-benzoquinone Imine-d₃) is the deuterium labeled NAPQI (HY-W017464). NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .

NAPQI-d3

NAPQI-d₃ (N-Acetyl-4-benzoquinone Imine-d₃) is the deuterium labeled NAPQI (HY-W017464). NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .

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NAPQI-d<sub>3</sub>

Inhibitors & Agonists

Isotope-Labeled Compounds