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Results for "

NADH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NADH Dehydrogenase (1) 17β-HSD (1) ADC Payload (1) AMPK (1) Antibiotic (4) Apoptosis (3) Autophagy (1) Bacterial (12) Biochemical Assay Reagents (2) Drug Derivative (1) Drug Isomer (1) Endogenous Metabolite (26) Fluorescent Dye (3) Fungal (2) Herbicide (3) IFNAR (1) Interleukin Related (1) IRAK (1) Isotope-Labeled Compounds (2) JAK (1) Keap1-Nrf2 (1) MDM-2/p53 (3) Mitochondrial Metabolism (7) NAMPT (1) Oxidative Phosphorylation (2) Parasite (5) PARP (1) Phosphoglycerate Dehydrogenase (PHGDH) (1) Quinone Reductase (2) Reactive Oxygen Species (ROS) (11) Reference Standards (6) Sigma Receptor (1) STAT (1) TNF Receptor (1) Wnt (1)
By Research Areas:	Cancer (21) Infection (20) Inflammation/Immunology (6) Metabolic Disease (24) Neurological Disease (4)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: NADH Dehydrogenase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-F0001

NADH disodium salt 5 Publications Verification Disodium NADH	Endogenous Metabolite	Metabolic Disease
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-F0001R

NADH disodium salt (Standard) Disodium NADH (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-146036

NADH-IN-1	Endogenous Metabolite	Metabolic Disease
NADH-IN-1 has NADH:ubiquinone oxidoreductase inhibitory activity with an IC₅₀ value of 27 μM. NADH-IN-1 can effectively stimulate glucose uptake in vitro. NADH-IN-1 is readily metabolised by the liver. NADH-IN-1 can be used for researching diabetes .

HY-113355

*NADH*	Endogenous Metabolite	Metabolic Disease
NADH is an orally active reduced coenzyme. NADH is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-175016

NADH-IN-3	Endogenous Metabolite	Infection Metabolic Disease
NADH-IN-3 (Compound C4-1) is a *NADH* inhibitor with a MIC of 4 μg/mL (13.042 μM) for type II NADH dehydrogenase of Mycobacterium tuberculosis (Mtb). NADH-IN-3 significantly interrupts ATP synthesis, shows potent inhibitory effects against mono (Rifampicin (HY-B0272) and Isoniazid (HY-B0329)) and multi drug-resistant (Mtb) strains and an anti-bactericidal activity against HepG2 cells with low cytotoxicity (SI: 16.52) .

HY-F0001A

NADH disodium hydrate Disodium NADH hydrate	Endogenous Metabolite	Metabolic Disease
NADH disodium salt (Disodium NADH) hydrate is an orally active reduced coenzyme. NADH disodium salt hydrate is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt hydrate plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-168146

NADH-IN-2	Endogenous Metabolite	Cancer
NADH-IN-2 (compund 8) is a Type II *NADH* dehydrogenase inhibitor .

HY-P3182

NADH oxidase	Biochemical Assay Reagents	Others
NADH oxidase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-154925

Thio-NADH	Biochemical Assay Reagents	Others
Thio-NADH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-142098

3′-Hydroxy-4′-O-methylglabridin	Reactive Oxygen Species (ROS)	Others
3′-Hydroxy-4′-O-methylglabridin is an antioxidant that is effective at preventing NADH-dependent peroxidation .

HY-P2807

L-Lactate dehydrogenase, Microorganism LAD	Endogenous Metabolite	Inflammation/Immunology Cancer
L-Lactate dehydrogenase, Microorganism (LAD) is a redox enzyme. L-Lactate dehydrogenase catalyzes the reduction of pyruvate to L-lactate by NADH in vivo with absolute enantiospecificity .

HY-159118

PC-Qz1	Bacterial	Infection
PC-Qz1 is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor with an IC₅₀ of 470 nM. PC-Qz1 has antibacterial activity .

HY-155023

Apoptosis inducer 13	Apoptosis Reactive Oxygen Species (ROS)	Cancer
Apoptosis inducer 13 (Compound Ru4) can induce cancer cell apoptosis, and inhibits cancer cell migration and invasion. Apoptosis inducer 13 converts coenzyme NADH to NAD ⁺, and increases intracellular ROS levels .

HY-P2807K

L-Lactate Dehydrogenase, bovine muscle	Endogenous Metabolite	Metabolic Disease
L-Lactate Dehydrogenase, bovine muscle is an oxidoreductase. L-Lactate Dehydrogenase, bovine muscle catalyzes the reversible conversion of lactate to pyruvate with the reduction of NAD+ to NADH .

HY-145985

CBR-3465	Bacterial	Infection
CBR-3465 is a mycobacterium tuberculosis (Mtb) *type II NADH* dehydrogenase** inhibitor, with the MIC of 0.16 μM against Mtb .

HY-145986

CBR-6672	Bacterial	Infection
CBR-6672 is a mycobacterium tuberculosis (Mtb) *type II NADH* dehydrogenase** inhibitor, with the MIC of 0.14 μM against Mtb .

HY-13675

ME-143 NV-143	Wnt Endogenous Metabolite	Cancer
ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo .

HY-W615108B

β-Nicotinamide mononucleotide, reduced form disodium NMNH disodium	Endogenous Metabolite	Cancer
β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is an orally active reduced version of β-Nicotinamide mononucleotide (HY-F0004). β-Nicotinamide mononucleotide, reduced form disodium can significantly increase the levels of NAD ⁺ and *NADH*, inhibit glycolysis, the tricarboxylic acid cycle, and cell growth, with its effects being dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT) .

HY-113128S

sn-Glycerol 3-phosphate-13C3 disodium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate- ¹³C₃ disodium is the ¹³C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .

HY-B0817

Pyridaben	Parasite	Infection
Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

HY-176270

ESC1002755	17β-HSD	Neurological Disease Cancer
ESC1002755 is a 17β-HSD10 inhibitor with an IC₅₀ of 19 nM. ESC1002755 has significant enzyme specificity with non-/uncompetitive inhibition against the cofactor NADH. ESC1002755 shows minimal cytotoxicity towards the HEK293 at 50 μM. ESC1002755 is promising for Alzheimer’s disease and hormone-dependent cancers (such as prostate, bone and colorectal cancer) research .

HY-B0817R

Pyridaben (Standard)	Reference Standards Parasite	Infection
Pyridaben (Standard) is the analytical standard of Pyridaben. This product is intended for research and analytical applications. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

HY-W008646R

7,8-Dihydro-L-biopterin (Standard)	Reference Standards Endogenous Metabolite	Others
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-176284

OXPHOS-IN-2	Oxidative Phosphorylation Mitochondrial Metabolism Apoptosis Reactive Oxygen Species (ROS) AMPK Keap1-Nrf2	Cancer
OXPHOS-IN-2 is an orally active OXPHOS inhibitor. OXPHOS-IN-2 exhibits potent inhibitory activity in PC9 (IC₅₀ = 12.3 nM) and Bxpc-3 cells (IC₅₀ = 250 nM in glucose medium, IC₅₀ = 17.5 nM in galactose medium). OXPHOS-IN-2 regulates the NADH/NAD ⁺ ratio and reduces ATP levels. OXPHOS-IN-2 induces tumor cells apoptosis by activating reactive oxygen species (ROS) and downregulating the level of Nrf2. OXPHOS-IN-2 can be used for research on cancer such as non-small cell lung cancer and pancreatic cancer .

HY-N10184

Paecilaminol FKI-0550	Others	Infection
Paecilaminol (FKI-0550) is potent NADH-fumarate reductase inhibitor. Paecilaminol exhibits an IC₅₀ value of 5.1 μM against Ascaris suum NADH-fumarate reductase .

HY-125778

Cochlioquinone B	Others	Metabolic Disease
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.

HY-160644

8PC	Bacterial	Infection
8PC is a the ligand of InhA-NADH-JPM, and can be used for study of tuberculosis .

HY-B0445A

NAD sodium Maximum Cited Publications 32 Publications Verification β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium	Endogenous Metabolite	Metabolic Disease
NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .

HY-P2800A

Diaphorase, clostridium sp.	Endogenous Metabolite	Metabolic Disease
Diaphorase from Clostridium sp. is responsible for catalyzing the oxidation of NADH or NADPH and is involved in regulating cellular energy metabolism .

HY-133965

Cinchonain IIa	Others	Inflammation/Immunology
Cinchonain IIa is an antioxidant agent with EC₅₀s of 6.8 μM and 26.5 μM for DPPH and PMS-NADH .

HY-P3186

Glucose dehydrogenase, recombinant Microorganisms	Endogenous Metabolite	Metabolic Disease
Glucose dehydrogenase, recombinant Microorganisms is a FDA-dependent oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP ⁺ to NADPH or, to a lesser extent, NAD ⁺ to NADH. Glucose dehydrogenase (GDH) accepts both NAD ⁺ and NADP ⁺ as cofactors and can be used for the regeneration of NADH and NADPH .

HY-142099

Hispaglabridin A	Reactive Oxygen Species (ROS)	Others
Hispaglabridin A is an antioxidant that is effective at inhibiting lipid peroxidation .

HY-120338

RYL-552	Mitochondrial Metabolism Parasite	Infection
RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a **P. falciparum NADH* dehydrogenase 2 (PfNDH2)*** inhibtor .

HY-114936

Piericidin A 4 Publications Verification AR-054	Bacterial ADC Payload Antibiotic Mitochondrial Metabolism	Infection Neurological Disease Cancer
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

HY-P3186A

NAD-dependent Glucose dehydrogenase GDH-NAD	Endogenous Metabolite	Metabolic Disease
NAD-dependent Glucose dehydrogenase (GDH-NAD) ((EC 1.1.1.47)) is a NAD-dependent oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP ⁺ to NADPH or, to a lesser extent, NAD ⁺ to NADH. Glucose dehydrogenase (GDH) accepts both NAD ⁺ and NADP ⁺ as cofactors and can be used for the regeneration of NADH and NADPH .

HY-163034

Antitumor photosensitizer-5	Apoptosis Reactive Oxygen Species (ROS)	Cancer
Antitumor photosensitizer-5 (Ru2) is a photosensitizer which effectively target tumor mitochondria with an IC₅₀ of 0.3 μM for phototoxicity to A549 cells. Under 460 nm light irradiation, antitumor photosensitizer-5 induces the generation of reactive oxygen species and NADH depletion, causes mitochondrial damage and activation of caspase-3, inducing apoptosis and suppressing cell migration. Antitumor photosensitizer-5 has the potential to prevent the growth of malignant tumors, therefore, shows the potential to be applied to photodynamic therapy .

HY-N7151

Aurachin D	Antibiotic Bacterial Fungal	Infection
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles .

HY-P3185

beta-Galactose dehydrogenase	Endogenous Metabolite	Metabolic Disease
beta-Galactose dehydrogenase can make conversion of galactose to galactonolactone and the concomitant reduction of NAD to the fluorescent NADH. beta-Galactose dehydrogenase can be used for the determination of galactose .

HY-Z0031

(R)-(-)-1,2-Propanediol	Endogenous Metabolite	Metabolic Disease
(R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes .

HY-125921

WST-3	Fluorescent Dye	Others
WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM .

HY-158421

MS-L6	Oxidative Phosphorylation Mitochondrial Metabolism	Cancer
MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect .

HY-147124

RIG012 3 Publications Verification	IFNAR	Infection Cancer
RIG012 is a potent RIG-I inhibitor with an IC₅₀ of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression .

HY-169203

Antifungal agent 119	Fungal	Cancer
Antifungal agent 119 (compund T23) is an antifungal agent that targets type I reduced NADH oxidoreductase. Antifungal agent 119 carries an azide group and can be used for click chemistry reactions. .

HY-145499

XTT sodium hydrate	Fluorescent Dye	Others
XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.

HY-P2996

NAD(P)H-Nitrate reductase	Others	Others
NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .

HY-157744

Coumarin–quinone conjugate	Mitochondrial Metabolism	Cancer
Coumarin–quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases which consists of a coumarin fluorophore and a ubiquinone analog. Coumarin–quinone conjugate can be used to measure the kinetic parameters of AIFM2/FSP1 for researches such as ferroptosis .

HY-P2765

Glycerol-3-phosphate dehydrogenase, rabbit muscle GPDH; α-Glycerophosphate dehydrogenase; Glycerol phosphate dehydrogenase	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate dehydrogenase, rabbit muscle (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate. Glycerol-3-phosphate dehydrogenase is a glycolytic enzyme and is responsible for the re-oxidation of NADH to NAD ⁺ and energy supply .

HY-P2765A

Glycerol-3-phosphate dehydrogenase, microorganism GPDH, microorganism; α-Glycerophosphate dehydrogenase, microorganism; Glycerol phosphate dehydrogenase, microorganism	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate dehydrogenase, microorganism (GPDH, microorganism) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate.Glycerol-3-phosphate dehydrogenase is a glycolytic enzyme and is responsible for the re-oxidation of NADH to NAD ⁺ and energy supply .

HY-117420

CM764	Sigma Receptor	Cancer
CM764 is an activator for sigma receptor with K_i of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD ⁺/NADH, and ATP levels, and decreases the concentration of ROS .

HY-126253

BI-4916 5 Publications Verification	Phosphoglycerate Dehydrogenase (PHGDH)	Infection Inflammation/Immunology Cancer
BI-4916 is a proagent of BI-4924. BI-4924 is a NADH/NAD ⁺-competitive PHGDH inhibitor. BI-4916 inhibits cancer cell migration. BI-4916 can be used for cancer, inflammation and infection study .

Cat. No.	Product Name	Type

HY-125921

WST-3	Dyes
WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM .

HY-136976

WST-1 3 Publications Verification	Dyes
WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm .

HY-145499

XTT sodium hydrate	Fluorescent Dyes/Probes
XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.

Cat. No.	Product Name	Type

HY-B0445A

NAD sodium 30+ Cited Publications β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium	Enzyme Substrates
NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .

HY-154925

Thio-NADH	Biochemical Assay Reagents
Thio-NADH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-F0001

NADH disodium salt 5 Publications Verification Disodium NADH	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-F0001R

NADH disodium salt (Standard) Disodium NADH (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-146036

NADH-IN-1	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADH-IN-1 has NADH:ubiquinone oxidoreductase inhibitory activity with an IC₅₀ value of 27 μM. NADH-IN-1 can effectively stimulate glucose uptake in vitro. NADH-IN-1 is readily metabolised by the liver. NADH-IN-1 can be used for researching diabetes .

HY-13675

ME-143 NV-143	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields Cancer	Wnt Endogenous Metabolite
ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo .

HY-W615108B

β-Nicotinamide mononucleotide, reduced form disodium NMNH disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is an orally active reduced version of β-Nicotinamide mononucleotide (HY-F0004). β-Nicotinamide mononucleotide, reduced form disodium can significantly increase the levels of NAD ⁺ and *NADH*, inhibit glycolysis, the tricarboxylic acid cycle, and cell growth, with its effects being dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT) .

HY-W008646R

7,8-Dihydro-L-biopterin (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-113355

*NADH*	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
NADH is an orally active reduced coenzyme. NADH is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-142098

3′-Hydroxy-4′-O-methylglabridin	Structural Classification Natural Products Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Reactive Oxygen Species (ROS)
3′-Hydroxy-4′-O-methylglabridin is an antioxidant that is effective at preventing NADH-dependent peroxidation .

HY-N10184

Paecilaminol FKI-0550	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Others
Paecilaminol (FKI-0550) is potent NADH-fumarate reductase inhibitor. Paecilaminol exhibits an IC₅₀ value of 5.1 μM against Ascaris suum NADH-fumarate reductase .

HY-125778

Cochlioquinone B	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.

HY-133965

Cinchonain IIa	Structural Classification Smilacaceae Source classification Phenols Polyphenols Plants Smilax sebeana Miq.	Others
Cinchonain IIa is an antioxidant agent with EC₅₀s of 6.8 μM and 26.5 μM for DPPH and PMS-NADH .

HY-142099

Hispaglabridin A	Structural Classification Natural Products Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Reactive Oxygen Species (ROS)
Hispaglabridin A is an antioxidant that is effective at inhibiting lipid peroxidation .

HY-114936

Piericidin A 4 Publications Verification AR-054	Structural Classification Neurological Disease Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Anticancer Disease Research Fields	Bacterial ADC Payload Antibiotic Mitochondrial Metabolism
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

HY-N7151

Aurachin D	Structural Classification Alkaloids Microorganisms Source classification Quinoline Alkaloids	Antibiotic Bacterial Fungal
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles .

HY-Z0031

(R)-(-)-1,2-Propanediol	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes .

HY-113128

sn-Glycerol 3-phosphate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

HY-113128A

sn-Glycerol 3-phosphate lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .

HY-113128B

sn-Glycerol 3-phosphate biscyclohexylammonium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
sn-Glycerol 3-phosphate biscyclohexylammonium salt is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate biscyclohexylammonium salt from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate biscyclohexylammonium salt for lipid metabolism .

HY-Z0031R

(R)-(-)-1,2-Propanediol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
(R)-(-)-1,2-Propanediol (Standard) is the analytical standard of (R)-(-)-1,2-Propanediol. This product is intended for research and analytical applications. (R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1].

HY-125365R

Rifamycin S (Standard)	Quinones Structural Classification Monophenols Microorganisms Source classification Phenols Naphthalene Quinones	Reference Standards Bacterial Reactive Oxygen Species (ROS) Antibiotic
Rifamycin S (Standard) is the analytical standard of Rifamycin S. This product is intended for research and analytical applications. Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .

HY-125365

Rifamycin S 1 Publications Verification	Infection Quinones Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Naphthalene Quinones Disease Research Fields	Bacterial Reactive Oxygen Species (ROS) Antibiotic
Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .

Species:	Human (1)
Tag:	His (4) Tag Free (3)
Source:	E. coli Cell-free (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P76856

	CYB5R1 Protein, Human (His) NADH-cytochrome b5 reductase 1; b5R.1; Humb5R2; NQO3A2	Human	E. coli
	CYB5R1 is an important member of the NADH-cytochrome b5 reductase family and plays a crucial role in fatty acid desaturation, cholesterol biosynthesis, drug metabolism, and erythrocyte methemoglobin reduction. Utilizing NADH, CYB5R1 promotes the reduction of cytochrome b5, contributing to enzymatic processes in lipid metabolism, sterol synthesis, and drug biotransformation. CYB5R1 Protein, Human (His) is the recombinant human-derived CYB5R1 protein, expressed by E. coli , with N-His labeled tag.

HY-P702179

	NADH dehydrogenase Protein, Gluconobacter oxydans NADH dehydrogenase	Others	E. coli
	NADH dehydrogenase is a protein complex involved in the electron transport chain of cellular respiration. It catalyzes the transfer of electrons from NADH to coenzyme Q, contributing to the generation of a proton gradient used for ATP synthesis. The protein plays a vital role in energy production within the mitochondria. NADH dehydrogenase Protein, Gluconobacter oxydans is the recombinant NADH dehydrogenase protein, expressed by E. coli , with tag free.

HY-P702180

	NADH dehydrogenase Protein type II, Gluconobacter oxydans GOX1675; NADH dehydrogenase type II	Others	E. coli
	NADH dehydrogenase Protein type II, Gluconobacter oxydans is the recombinant NADH dehydrogenase protein type II, Gluconobacter oxydans, expressed by E. coli, with tag free.

HY-P702181

	NADH dehydrogenase Protein type II, Gluconobacter oxydans (His) GOX1675; NADH dehydrogenase type II	Others	E. coli
	NADH dehydrogenase Protein type II, Gluconobacter oxydans (His) is the recombinant NADH dehydrogenase protein type II, Gluconobacter oxydans, expressed by E. coli, with N-6*His labeled tag.

HY-P702146

	Aldehyde reductase Protein, Gluconobacter oxydans NADH-dependent iron-containing alcohol dehydrogenase	Others	E. coli
	Aldehyde reductase Protein, Gluconobacter oxydans is the recombinant Aldehyde reductase protein, expressed by E. coli, with tag free.

HY-P702147

	Aldehyde reductase Protein, Gluconobacter oxydans (His) ADH; NADH-dependent iron-containing alcohol dehydrogenase	Others	E. coli
	Aldehyde reductase Protein, Gluconobacter oxydans (His) is the recombinant Aldehyde reductase protein, expressed by E. coli, with N-6*His labeled tag.

HY-P702384

	NAD2 Protein, Psoroptes ovis (Cell-Free, His) NADH dehydrogenase subunit 2; nad2	Others	E. coli Cell-free
	NAD2 Protein, Psoroptes ovis (Cell-Free, His) is the recombinant NAD2 protein, expressed by E. coli Cell-free, with N-10*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-113128S

sn-Glycerol 3-phosphate-13C3 disodium
sn-Glycerol 3-phosphate- ¹³C₃ disodium is the ¹³C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .

HY-B0860S

Diuron-d6

Diuron-d₆ is the deuterium labeled Diuron (HY-B0860). Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .

HY-B0817S

Pyridaben-d13

Pyridaben-d₁₃ is the deuterium labeled Pyridaben . Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82344

	MT ND1 Antibody (YA2089) MT-ND1; MTND1; NADH1; ND1; NADH-ubiquinone oxidoreductase chain 1; NADH dehydrogenase subunit 1	WB	Human, Mouse, Rat
	MT ND1 Antibody (YA2089) is a non-conjugated IgG antibody, targeting MT ND1, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). MT ND1 Antibody (YA2089) can be used for WB experiment in human, mouse, rat background.

HY-P82790

	NDUFS1 Antibody (YA2535) NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit; mitochondrial; Complex I-75kD; CI-75kD	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	NDUFS1 Antibody (YA2535) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2535), targeting NDUFS1, with a predicted molecular weight of 79 kDa (observed band size: 75 kDa). NDUFS1 Antibody (YA2535) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P86984

	NDUFV2 Antibody (YA6677) 24kDa subunit of Complex I antibody; CI-24k antibody; complex I 24kDa subunit antibody; complex I, mitochondrial respiratory 2 antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) flavoprotein 2 antibody; NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa antibody; NADH dehydrogenase [ubiquinone] flavoprotein 2 antibody; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial antibody; NADH ubiquinone oxidoreductase 24 kDa subunit antibody; 24kDa subunit of Complex I antibody; CI-24k antibody; complex I 24kDa subunit antibody; complex I, mitochondrial respiratory 2 antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) flavoprotein 2 antibody; NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa antibody; NADH dehydrogenase [ubiquinone] flavoprotein 2 antibody; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial antibody; NADH ubiquinone oxidoreductase 24 kDa subunit antibody; NADH-ubiquinone oxidoreductase 24 kDa subunit antibody; NADH-ubiquinone oxidoreductase flavoprotein 2 antibody; NDUFV2 antibody; NDUV2_HUMAN antibody; nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit antibody; Ubiquinoneflavoprotein 2 antibody; Ubiquinoneflavoprotein 2, mitochondrial precursor antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P81585

	NDUFB10 Antibody (YA1330) NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Complex I-PDSW; CI-PDSW; NADH-ubiquinone oxidoreductase PDSW subunit	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	NDUFB10 Antibody (YA1330) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1330), targeting NDUFB10, with a predicted molecular weight of 21 kDa (observed band size: 21 kDa). NDUFB10 Antibody (YA1330) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P86291

	NDUFA1 Antibody (YA5983) NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 ; Complex I-MWFE; CI-MWFE; NADH-ubiquinone oxidoreductase MWFE subunit;	WB, IHC-P, IP	Human
	NDUFA1 Antibody (YA5983) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NDUFA1. It can be applicated for WB, IHC-P, IP assays, in the background of human.

HY-P81601

	NDUFS3 Antibody (YA1346) NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit	WB	Human, Mouse
	NDUFS3 Antibody (YA1346) is a non-conjugated IgG antibody, targeting NDUFS3, with a predicted molecular weight of 30 kDa (observed band size: 26 kDa). NDUFS3 Antibody (YA1346) can be used for WB experiment in human, mouse background.

HY-P86511

	NDUFS3 Antibody (YA6203) NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	NDUFS3 Antibody (YA6203) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NDUFS3. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P83352

	NDUFS2 Antibody (YA3097) NADH dehydrogenase (ubiquinone) Fe-S protein 2; 49kDa; CI-49	WB, IHC-P, IP	Human
	NDUFS2 Antibody (YA3097) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3097), targeting NDUFS2, with a predicted molecular weight of 53 kDa (observed band size: 49 kDa). NDUFS2 Antibody (YA3097) can be used for WB, IHC-P, IP experiment in human background.

HY-P81595

	NDUFB9 Antibody (YA1340) NDUFB9; LYRM3; UQOR22; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Complex I-B22; CI-B22; LYR motif-containing protein 3; NADH-ubiquinone oxidoreductase B22 subunit	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	NDUFB9 Antibody (YA1340) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1340), targeting NDUFB9, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). NDUFB9 Antibody (YA1340) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P86983

	NDUFAB1 Antibody (YA6676) ACP antibody; ACPM_HUMAN antibody; Acyl carrier protein antibody; Acyl carrier protein mitochondrial antibody; CI SDAP antibody; CI-SDAP antibody; FASN 2A antibody; FASN2A antibody; MGC65095 antibody; Mitochondrial acyl carrier protein antibody; ACP antibody; ACPM_HUMAN antibody; Acyl carrier protein antibody; Acyl carrier protein mitochondrial antibody; CI SDAP antibody; CI-SDAP antibody; FASN 2A antibody; FASN2A antibody; MGC65095 antibody; Mitochondrial acyl carrier protein antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 8kDa antibody; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 antibody; NADH ubiquinone oxidoreductase 9.6 kDa subunit antibody; NADH ubiquinone oxidoreductase SDAP subunit antibody; NADH-ubiquinone oxidoreductase 9.6 kDa subunit antibody; NDUFAB 1 antibody; ndufab1 antibody; SDAP antibody	WB, IHC-P, FC	Human, Mouse, Rat