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Mycobacteria

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (41) Autophagy (3) Bacterial (77) Biochemical Assay Reagents (1) Carbonic Anhydrase (1) Dihydrofolate reductase (DHFR) (2) DNA Stain (1) DNA/RNA Synthesis (3) Dopamine Receptor (3) Endogenous Metabolite (1) Fungal (4) Isotope-Labeled Compounds (1) Lipase (1) Mitophagy (3) Parasite (1) Thymidylate Synthase (8) Topoisomerase (1)
By Research Areas:	Cancer (7) Infection (78) Inflammation/Immunology (6) Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0329

Isoniazid 4 Publications Verification INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .

HY-B0901A

Bromperidol hydrochloride 2 Publications Verification R-11333 hydrochloride	Dopamine Receptor Bacterial	Neurological Disease
Bromperidol (R-11333) hydrochloride possesses antipsychotic activity, with a high affinity for central dopamine receptors D₂. Bromperidol hydrochloride can kill Mycobacteria in a synergistic manner with Spectinomycin .

HY-B0901

Bromperidol 2 Publications Verification R-11333	Dopamine Receptor Bacterial	Infection Neurological Disease
Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D₂. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin .

HY-161135

TBAJ-5307	Bacterial	Infection
TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo .

HY-135285

Rifamexil	Antibiotic Bacterial	Infection
Rifamexil is an antibiotic Rifamycin (HY-B1907A) derivative that is active against Mycobacterium avium complex and other *mycobacteria* .

HY-B0329R

Isoniazid (Standard)	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid (Standard) is the analytical standard of Isoniazid. This product is intended for research and analytical applications. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .

HY-N14008

Carriomycin	Antibiotic Bacterial Fungal Parasite	Infection
Carriomycin is an antibiotic that can be isolated from Streptomyces hygroscopicus. Carriomycin can inhibit Gram-positive bacteria, *mycobacteria, yeasts* and fungi, and is also an effective anticoccidial agent .

HY-146702

MtTMPK-IN-8	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-8 (compound 27) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor. MtTMPK-IN-8 has sub-micromolar activity against mycobacteria (MICs = 0.78~9.4 μM) without significant cytotoxicity. MtTMPK-IN-8 can be used for researching tuberculosis .

HY-146701

MtTMPK-IN-7	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-7 (compound 26) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 47 μM. MtTMPK-IN-7 has sub-micromolar activity against mycobacteria (MICs = 2.3~4.7 μM) without significant cytotoxicity. MtTMPK-IN-7 can be used for researching tuberculosis .

HY-146703

MtTMPK-IN-9	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-9 (compound 28) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 48 μM. MtTMPK-IN-9 has sub-micromolar activity against mycobacteria (MICs = 6.25~9.4 μM) without significant cytotoxicity. MtTMPK-IN-9 can be used for researching tuberculosis .

HY-148478

MMV688845 (R)-GSK1729177A	DNA/RNA Synthesis	Infection
MMV688845 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy .

HY-A0155

Viomycin	Antibiotic Bacterial	Cancer
Viomycin is a potent antibiotic against Mycobacteria. Viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis .

HY-145301

Mycobactin-IN-1	Bacterial	Infection
Mycobactin-IN-1 (compound 44), a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway .

HY-118481

H-Pro-Glu-OH	Lipase	Infection
H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway .

HY-120733

Calpinactam FKI-4905	Bacterial Endogenous Metabolite	Infection Inflammation/Immunology
Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively .

HY-N13971

Bamicetin	Bacterial	Infection
Bamicetin is mainly resistant to Gram-positive bacteria and Mycobacteria .

HY-N14913

Adenomycin	Antibiotic Bacterial	Infection
Adenomycin is an antibiotic that is effective against a wide range of mycobacteria .

HY-N14664

Actithiazic acid	Antibiotic Bacterial	Infection
Actithiazic acid is a nitrogen- and sulfur-containing antibiotic that primarily against mycobacteria .

HY-W748035

Etamycin A	Antibiotic Bacterial	Infection
Etamycin A is an ester peptide antibiotic. Mainly resistant to Gram-positive bacteria and mycobacteria .

HY-N14902

Mimosamycin	Antibiotic Bacterial	Infection
Mimosamycin is an antibiotic. Mimosamycin has activity against mycobacteria and streptomyces resistant strains .

HY-N14727

Primycin	Antibiotic Bacterial	Infection
Primycin is a macrolide antibiotic. Primycin is active against Gram-positive bacteria, mycobacteria and protozoa .

HY-N14469

Sakyomicin C	Antibiotic Bacterial	Infection
Sakyomicin C is a Benzoquinone antibiotic. Sakyomicin C has activity against Gram-positive bacteria and mycobacteria .

HY-N14803

Nanaomycin B	Antibiotic Bacterial Fungal	Infection
Nanaomycin B is an antibiotic. Nanaomycin B has anti-Gram-positive bacteria, mycobacteria, mycoplasma and fungi activity .

HY-N13995

Serratamolide	Antibiotic Bacterial Fungal	Infection
Serratamolide is a depsipeptide antibiotic. Serratamolide has anti-Gram-positive bacteria, mycobacteria and fungi activity, but the activity is weak .

HY-118553

Saframycin D	Bacterial	Infection
Saframycin D has the effect of anti-Gram-positive bacteria. Saframycin D also has weak activity against mycobacteria .

HY-N14541

Saframycin B	Bacterial	Infection
Saframycin B has the effect of anti-Gram-positive bacteria. Saframycin B also has weak activity against mycobacteria .

HY-N14538

Saframycin E	Bacterial	Infection
Saframycin E has the effect of anti-Gram-positive bacteria. Saframycin B also has weak activity against mycobacteria .

HY-121136A

Chartreusin sodium	Antibiotic Bacterial	Infection
Chartreusin sodium is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .

HY-N14485

Nebramycin Ⅳ	Antibiotic Bacterial	Infection
Nebramycin IV is an aminoglycoside antibiotic. Nebramycin IV has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria .

HY-121136

Chartreusin	Antibiotic Bacterial	Infection
Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .

HY-N14475

Sakyomicin B	Antibiotic Bacterial	Infection
Sakyomicin B is a Benzoquinone antibiotic found in the strain of Nocardia sp. M-53. Sakyomicin B has activity against Gram-positive bacteria and mycobacteria .

HY-146699

MtTMPK-IN-5	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-5 (compound 17) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 34 μM. MtTMPK-IN-5 combines favorable enzyme inhibitory activity with significant activity against M. tuberculosis (MIC = 12.5 μM). MtTMPK-IN-5 can be used for researching tuberculosis .

HY-W506116

Ostruthin Ostruthine	Bacterial	Infection
Ostruthin (Ostruthine) is an antimycobacterial coumarin, that can be isolated from the roots of Peucedanum ostruthium. Ostruthin causes a marked inhibition of the growth of gram-positive micro-organisms .

HY-146700

MtTMPK-IN-6	Bacterial Thymidylate Synthase	Infection
MtTMPK-IN-6 (compound 1) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC₅₀ value of 29 μM. MtTMPK-IN-6 can be used for researching tuberculosis .

HY-156359

Tuberculosis inhibitor 10	Others	Others
Tuberculosis inhibitor 10 shows moderate inhibitory effect on the enzymatic activity of MSMEG_6649. Tuberculosis inhibitor 10 enhances the inhibitory activity of PAS against mycobacteria .

HY-N14677

Pillaromycin A	Bacterial	Infection Cancer
Pillaromycin A has anti-mycobacteria, Gram-positive bacteria and Gram-negative bacteria effects, but the effect of anti-Gram-negative bacteria is weak. Pillaromycin A also has antitumor activity .

HY-D1543

Pyronin B	DNA Stain	Infection
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor .

HY-170519

K13787	Bacterial	Infection
K13787 is an acetohydroxyacid synthase (AHAS) inhibitor with antibacterial activity. K13787 has antibacterial activity against a variety of nontuberculous mycobacteria (NTM) and clarithromycin (CLR) resistant strains .

HY-130511

FCE 22250	Bacterial	Infection
FCE 22250 is a 3-azinomethylrifamycin with long-term in vivo persistence and good oral absorption. FCE 22250 shows superior efficacy against a broad antimicrobial spectrum including mycobacteria .

HY-145302

Mycobactin-IN-2	Bacterial	Infection
Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway .

HY-10392

Sutezolid 4 Publications Verification PNU-100480; U-100480; PF-02341272	Bacterial Antibiotic	Infection
Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .

HY-162503

ST166 free acid	Bacterial	Infection
ST166 free acid is a inhibitor of formation of the PhoP-DNA complex with the IC₅₀ values of 18 and 24 μM against PhoP and MtrAC binding with DNA, respectively. ST166 free acid shows antibacterial activity against Macrobacterium marinum .

HY-122289

Metioprim	Dihydrofolate reductase (DHFR) Bacterial	Infection
Metioprim is a competitive inhibitor of bacterial Dihydrofolate reductase (DHFR). Metioprim has inhibitory activity against anaerobic bacteria. Metioprim shows synergistic activity in combination with DDS (HY-B0688) against E. coli. and various mycobacteria .

HY-B0329S

Isoniazid-d4 INH-d₄; Isonicotinic acid hydrazide-d₄; Isonicotinic hydrazide-d₄	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-172263

KU13	Antibiotic Bacterial	Infection
KU13 is an inhibitor of nontuberculous mycobacteria (NTM). The minimum inhibitory concentrations (MIC) of KU13 against Mycobacterium and E. coli are 0.032-8 μg/mL and 2 μg/mL, respectively. KU13 can be used for research in the field of anti-infection .

HY-119188

Saframycin A	Bacterial	Infection Cancer
Saframycin A has the effect of anti-Gram-positive bacteria. Saframycin A also has weak activity against Gram-negative bacteria and mycobacteria. Saframycin A has the effect of inhibiting mouse lymphocyte L-1210 with an ID₅₀ of 0.0056 μM .

HY-B0901R

Bromperidol (Standard) 2 Publications Verification R-11333 (Standard)	Dopamine Receptor Bacterial	Infection Neurological Disease
Bromperidol (Standard) is the analytical standard of Bromperidol. This product is intended for research and analytical applications. Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D₂. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin .

HY-N14627

Liposidomycin A	Bacterial	Infection
Liposidomycin A has antibacterial effect, but the antibacterial activity is weak. Liposidomycin A has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin A has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-N1969

3,3'-Di-O-methylellagic acid 3,8-Di-O-methylellagic acid	Bacterial	Infection
3,3'-Di-O-methylellagic acid obtained from Euphorbia adenochlora selectively inhibits the formation of acid-fastness in mycobacteria without retardation of their growth. 3,3'-di-O-methylellagic acid as a hepatoprotective compound is apparently due to its antioxidative effect .

HY-162782A

V–C6–Bg-PhCl TFA	Antibiotic Bacterial	Infection
V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria .

Cat. No.	Product Name	Type

HY-D1543

Pyronin B	Fluorescent Dyes/Probes
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N14008

Carriomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Fungal Parasite
Carriomycin is an antibiotic that can be isolated from Streptomyces hygroscopicus. Carriomycin can inhibit Gram-positive bacteria, *mycobacteria, yeasts* and fungi, and is also an effective anticoccidial agent .

HY-120733

Calpinactam FKI-4905	Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Inflammation/Immunology	Bacterial Endogenous Metabolite
Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively .

HY-N13971

Bamicetin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Bamicetin is mainly resistant to Gram-positive bacteria and Mycobacteria .

HY-N14913

Adenomycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Adenomycin is an antibiotic that is effective against a wide range of mycobacteria .

HY-N14664

Actithiazic acid	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Actithiazic acid is a nitrogen- and sulfur-containing antibiotic that primarily against mycobacteria .

HY-W748035

Etamycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Etamycin A is an ester peptide antibiotic. Mainly resistant to Gram-positive bacteria and mycobacteria .

HY-N14902

Mimosamycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Mimosamycin is an antibiotic. Mimosamycin has activity against mycobacteria and streptomyces resistant strains .

HY-N14727

Primycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Primycin is a macrolide antibiotic. Primycin is active against Gram-positive bacteria, mycobacteria and protozoa .

HY-N14469

Sakyomicin C	Quinones Structural Classification Microorganisms Source classification Benzene Quinones	Antibiotic Bacterial
Sakyomicin C is a Benzoquinone antibiotic. Sakyomicin C has activity against Gram-positive bacteria and mycobacteria .

HY-N14803

Nanaomycin B	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Fungal
Nanaomycin B is an antibiotic. Nanaomycin B has anti-Gram-positive bacteria, mycobacteria, mycoplasma and fungi activity .

HY-N13995

Serratamolide	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Fungal
Serratamolide is a depsipeptide antibiotic. Serratamolide has anti-Gram-positive bacteria, mycobacteria and fungi activity, but the activity is weak .

HY-118553

Saframycin D	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Saframycin D has the effect of anti-Gram-positive bacteria. Saframycin D also has weak activity against mycobacteria .

HY-N14541

Saframycin B	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Saframycin B has the effect of anti-Gram-positive bacteria. Saframycin B also has weak activity against mycobacteria .

HY-N14538

Saframycin E	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Saframycin E has the effect of anti-Gram-positive bacteria. Saframycin B also has weak activity against mycobacteria .

HY-121136A

Chartreusin sodium	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Chartreusin sodium is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .

HY-N14485

Nebramycin Ⅳ	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Nebramycin IV is an aminoglycoside antibiotic. Nebramycin IV has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria .

HY-121136

Chartreusin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage .

HY-N14475

Sakyomicin B	Quinones Structural Classification Microorganisms Source classification Benzene Quinones	Antibiotic Bacterial
Sakyomicin B is a Benzoquinone antibiotic found in the strain of Nocardia sp. M-53. Sakyomicin B has activity against Gram-positive bacteria and mycobacteria .

HY-N14677

Pillaromycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Pillaromycin A has anti-mycobacteria, Gram-positive bacteria and Gram-negative bacteria effects, but the effect of anti-Gram-negative bacteria is weak. Pillaromycin A also has antitumor activity .

HY-119188

Saframycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Saframycin A has the effect of anti-Gram-positive bacteria. Saframycin A also has weak activity against Gram-negative bacteria and mycobacteria. Saframycin A has the effect of inhibiting mouse lymphocyte L-1210 with an ID₅₀ of 0.0056 μM .

HY-N14627

Liposidomycin A	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Liposidomycin A has antibacterial effect, but the antibacterial activity is weak. Liposidomycin A has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin A has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-N1969

3,3'-Di-O-methylellagic acid 3,8-Di-O-methylellagic acid	Structural Classification Classification of Application Fields Euphorbia adenochlora Source classification Plants Infection Ketones, Aldehydes, Acids Combretaceae Phenols Polyphenols Euphorbiaceae Terminalia chebula Retz. Disease Research Fields	Bacterial
3,3'-Di-O-methylellagic acid obtained from Euphorbia adenochlora selectively inhibits the formation of acid-fastness in mycobacteria without retardation of their growth. 3,3'-di-O-methylellagic acid as a hepatoprotective compound is apparently due to its antioxidative effect .

HY-N14629

Liposidomycin C	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Liposidomycin C has antibacterial effect, but the antibacterial activity is weak. Liposidomycin C has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin C has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-N14628

Liposidomycin B	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Liposidomycin B has antibacterial effect, but the antibacterial activity is weak. Liposidomycin B has strong inhibition of mycobacteria (MIC is 0.16 μg/mL). Liposidomycin B has the function of inhibiting glycopeptide biosynthesis, and can inhibit the glycopeptide biosynthesis of E.coli with an IC₅₀ of 0.03 μg/mL .

HY-B1864A

Kasugamycin hydrochloride 1 Publications Verification Ksg hydrochloride	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Biological Pesticide Research Plant agriculture research Agricultural Research Infection Microorganisms Antibiotics Resistance Selection Disease Research Fields	Antibiotic Bacterial
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .

HY-N10069

Bonducellin	Structural Classification Flavonoids Leguminosae Caesalpinia sappan L. Source classification Plants Other Flavonoids	Bacterial
Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L) .

HY-B1864AR

Kasugamycin hydrochloride (Standard) Ksg hydrochloride (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics Plant agriculture research	Antibiotic Bacterial
Kasugamycin (Ksg) hydrochloride (Standard) is the analytical standard of Kasugamycin hydrochloride (HY-B1864A). This product is intended for research and analytical applications. Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models .

HY-122292

Celastramycin A	Structural Classification Animals Antibiotics Source classification	Antibiotic Bacterial
Celastramycin A is an antibiotic isolated from Streptomyces MaB-QuH-8, which exhibits antimicrobial activity against series of gram-negative bacteria and mycobacteria, with MICs between 0.05-3.1 μg/ml . Celastramycin A exhibits immunosuppressing efficacy in ex vivo Drosophila through immune deficiency pathway (IC₅₀ of 0.008 μg/ml), inhibits the immunoresponse in human innate immunity through TNF-α signaling, inhibits IL-8 production in HUEVCs with IC₅₀ of 0.06 μg/ml .

HY-16566R

Kanamycin (Standard) Kanamycin A (Standard)	Microorganisms Source classification	Antibiotic Bacterial
Kanamycin (Standard) is the analytical standard of Kanamycin. This product is intended for research and analytical applications. Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia[1][2][3][4].

HY-16566AR

Kanamycin (sulfate) (Standard)	Structural Classification Plant Cell Culture Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Resistance Selection Source classification Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .

HY-16566A

Kanamycin sulfate 10+ Cited Publications Kanamycin A sulfate	Structural Classification Anti-inflammation/Immunoregulatory Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Fields	Bacterial Antibiotic
Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .

Cat. No.	Product Name	Chemical Structure

HY-B0329S

Isoniazid-d4
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-10392S

Sutezolid-13C4
Sutezolid- ¹³C₄ (PNU-100480- ¹³C₄) is ¹³C labeled Sutezolid. Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .

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