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  3. Fluorescent Dye
  4. Cy3-NO2-Tre

Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent probe that specifically labels Mycobacterium tuberculosis (Mtb). Cy3-NO2-tre generated fluorescence after activation by a specific nitroreductase, Rv3368c, which is conserved in the Mycobacteriaceae. Cy3-NO2-tre effectively imaged mycobacteria within infected host cells, tracked the infection process, and visualized Mycobacterium smegmatis being endocytosed by macrophages (Ex/Em= 540-550/575-625 nm).

For research use only. We do not sell to patients.

Cy3-NO2-Tre Chemical Structure

Cy3-NO2-Tre Chemical Structure

CAS No. : 3012597-48-4

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Cy3-NO2-Tre Related Antibodies

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Description

Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent probe that specifically labels Mycobacterium tuberculosis (Mtb). Cy3-NO2-tre generated fluorescence after activation by a specific nitroreductase, Rv3368c, which is conserved in the Mycobacteriaceae. Cy3-NO2-tre effectively imaged mycobacteria within infected host cells, tracked the infection process, and visualized Mycobacterium smegmatis being endocytosed by macrophages (Ex/Em= 540-550/575-625 nm)[1].

Molecular Weight

981.92

Formula

C48H61BrN4O13
CAS No.
SMILES

CC1(C)C2=CC=CC=C2[N+](CC3=CC=C(C=C3)[N+]([O-])=O)=C1/C=C/C=C4N(C5=CC=CC=C5C/4(C)C)CCCCCC(NC[C@H]6O[C@@H]([C@@H]([C@H]([C@@H]6O)O)O)O[C@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)=O.[Br-]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Cy3-NO2-Tre Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cy3-NO2-Tre3012597-48-4Fluorescent DyeInhibitorinhibitorinhibit

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