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Microbial secondary metabolite

" in MedChemExpress (MCE) Product Catalog:

24

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1

Biochemical Assay Reagents

1

Peptides

21

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1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N14927
    Phepropeptin A

    		Proteasome Inflammation/Immunology
    Phepropeptin A, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 21 μg/mL .
    Phepropeptin A
  • HY-N14928
    Phepropeptin B

    		Proteasome Inflammation/Immunology
    Phepropeptin B, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 11 μg/mL .
    Phepropeptin B
  • HY-N14940
    Phepropeptin D

    		Proteasome Inflammation/Immunology
    Phepropeptin D, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 7.8 μg/mL .
    Phepropeptin D
  • HY-N14929
    Phepropeptin C

    		Proteasome Inflammation/Immunology
    Phepropeptin C, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 12.5 μg/mL .
    Phepropeptin C
  • HY-N16423
    Metenaticin A

    		Endogenous Metabolite Others
    Metenaticin A (Compound 8), a polyketide, is a microbial secondary metabolite. Metenaticin A can be isolated from Streptomyces violaceoruber TU22 .
    Metenaticin A
  • HY-N16445
    Strevertene A

    (-)-Strevertene A

    		 Endogenous Metabolite Antibiotic Fungal Infection
    Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants .
    Strevertene A
  • HY-N16443
    Sporminarin A

    		Endogenous Metabolite Fungal Bacterial Infection
    Sporminarin A (Compound 1), a polyketide, is a microbial secondary metabolite. Sporminarin A can be isolated from the Sporormiella minimoides. Sporminarin A has significant antifungal activity against Aspergillus flavus with an MIC50 of 25  μg/mL. Sporminarin A also has antibacterial activity against Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 14053) .
    Sporminarin A
  • HY-N16457
    5,6-Dihydro-6-hydroxypenicillic acid

    		Endogenous Metabolite Influenza Virus Infection
    5,6-Dihydro-6-hydroxypenicillic acid (Compound 6) is a microbial secondary metabolite. 5,6-Dihydro-6-hydroxypenicillic acid can be isolated from the endophytic fungus Talaromyces sp. CPCC 400783 of Reynoutria japonica Houtt. 5,6-Dihydro-6-hydroxypenicillic acid has antiviral activity against influenza A virus with an IC50 of 65.45 μM .
    5,6-Dihydro-6-hydroxypenicillic acid
  • HY-N16442
    Pyrrocidine B

    		Endogenous Metabolite Prolyl Endopeptidase (PREP) Cancer
    Pyrrocidine B (Compound 6), an alkaloid, is a microbial secondary metabolite. Pyrrocidine B can be isolated from the endophytic fungus Neonectria ramulariae Wollenw KS-246. Pyrrocidine B has significant cytotoxicity against leukemia cells (IC50 of 4.6  μM for HL60 cells) with a weak Prolyl oligopeptidase (POP) inhibitory activity .
    Pyrrocidine B
  • HY-N16441
    Pulvic acid

    		Endogenous Metabolite Influenza Virus Infection
    Pulvic acid (Compound 3), a butenolide, is a microbial secondary metabolite. Pulvic acid can be isolated from the marine-derived fungus Aspergillus terreus Gwq-48. Pulvic acid has significant antiviral activity with an IC50 of 29.1 μg/mL for influenza A H1N1 virus. Pulvic acid can be used for influenza virus infections research .
    Pulvic acid
  • HY-N12106
    Neosartoricin

    Fumicycline

    		 Endogenous Metabolite Fungal Infection
    Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence .
    Neosartoricin
  • HY-119675
    Albonoursin

    		Bacterial Infection Cancer
    Albonoursin, a microbial secondary metabolite, is an antibacterial peptide. Albonoursin displays antibacterial and antitumor activities .
    Albonoursin
  • HY-N13292
    Actinorhodin

    		Antibiotic Bacterial Infection
    Actinorhodin is a blue-pigmented, redox-active microbial secondary metabolite. Actinorhodin is a potent, bacteriostatic, pH-responsive antibiotic. Actinorhodin exhibits antimicrobial activity against Gram-positive bacteria .
    Actinorhodin
  • HY-N16429
    Neosartoricin D

    		Endogenous Metabolite Others
    Neosartoricin D, a polyketide, is a microbial secondary metabolite. Neosartoricin D can be isolated from the cultural of Aspergillus nidulans. Neosartoricin D is an analog of Neosartoricin B (HY-N10311). Neosartoricin B is the secondary metabolite, which can be produced by Aspergillus nidulans. Neosartoricin B may regulate immunomodulatory effects with the host during infection and colonization by pathogenic fungi .
    Neosartoricin D
  • HY-N13886
    Anicequol

    		Endogenous Metabolite Cancer
    Anicequol, a microbial secondary metabolites, is an anchorage-independent growth of tumor cells inhibitor. Anicequol inhibits the anchorage-independent growth of human colon cancer DLD-1 cells with the IC50 of 1.2 μM .
    Anicequol
  • HY-N5158B
    (5S)-Neosamine C

    		Antibiotic Endogenous Metabolite Infection
    (5S)-Neosamine C is an aminocyclic alcohol antibiotic derived from microbial secondary metabolites. (5S)-Neosamine C has a cyclized structure and can be used for biosynthesis of Neomycins (HY-B0470).
    (5S)-Neosamine C
  • HY-Y0669S
    Pipecolic acid-d9

    		Isotope-Labeled Compounds Endogenous Metabolite Ferroptosis YAP Glutathione Peroxidase Infection
    Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy .
    Pipecolic acid-d9
  • HY-N13891
    Arisostatin A

    		Antibiotic Bacterial Apoptosis Infection Cancer
    Arisostatin A, a microbial secondary metabolite, is an antibiotic against Gram-positive bacteria and shown to possess potent anti-tumor properties. Arisostatin A induces apoptosis through the activation of caspase-3 and reactive oxygen species (ROS) generation in AMC-HN-4 cells .
    Arisostatin A
  • HY-Y0669R
    Pipecolic acid (Standard)

    		Reference Standards Endogenous Metabolite YAP Glutathione Peroxidase Ferroptosis Neurological Disease Metabolic Disease Inflammation/Immunology
    Pipecolic acid (Standard) is the analytical standard of Pipecolic acid. This product is intended for research and analytical applications. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy .
    Pipecolic acid (Standard)
  • HY-P11338
    Microcyclamide

    		Endogenous Metabolite Cancer
    Microcyclamide (Compound 1), a cytotoxic cyclic hexapeptide, is a microbial secondary metabolite. Microcyclamide can be isolated from the cyanobacterium Microcystis aeruginosa. Microcyclamide has moderate cytotoxicity against P388 murine leukemia cells with an IC50 of 1.2 μg/mL. Microcyclamide can be used for cancers research .
    Microcyclamide
  • HY-N12229
    Penipurdin A

    		Endogenous Metabolite Bacterial Infection
    Penipurdin A (Compound 1), an anthraquinone, is a microbial secondary metabolite. Penipurdin A can be isolated from the soil fungus Penicillium purpurogenum SC0070. Penipurdin A has no significant cytotoxicity against cancer cells, such as A549, HepG2 and Hela cells. Penipurdin A has antibacterial activity against Enterococcus faecalis and Staphylococcus aureus .
    Penipurdin A
  • HY-N16428
    Neoaspergillic acid

    NSC 356436

    		 Endogenous Metabolite Fungal Bacterial Infection Cancer
    Neoaspergillic acid (NSC 356436) (Compound 2) is a microbial secondary metabolite. Neoaspergillic acid can be isolated from the endophytic fungus Aspergillus sp. SPH2. Neoaspergillic acid has potent antifungal activity against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum. Neoaspergillic acid appears during the exponential phase of fungal growth. Neoaspergillic acid also antitumor and antibacterial effects .
    Neoaspergillic acid
  • HY-N16394
    4-Hydroxyscytalone

    		Endogenous Metabolite Cancer
    4-Hydroxyscytalone (Compound 3) is a microbial secondary metabolite. 4-Hydroxyscytalone can be isolated from the oak fungus Diplodia corticola. 4-Hydroxyscytalone has toxicity against Artemia salina with a LC50 of 90.6 μ/mL, but no significant antifungal activity. 4-Hydroxyscytalone can be used for cancer therapy research .
    4-Hydroxyscytalone
  • HY-W751002
    Orthosporin

    (+)-Orthosporin

    		 Endogenous Metabolite Bacterial HIV Reverse Transcriptase Infection
    Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity .
    Orthosporin

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