2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite Prolyl Endopeptidase (PREP)
  4. Pyrrocidine B

Pyrrocidine B (Compound 6), an alkaloid, is a microbial secondary metabolite. Pyrrocidine B can be isolated from the endophytic fungus Neonectria ramulariae Wollenw KS-246. Pyrrocidine B has significant cytotoxicity against leukemia cells (IC50 of 4.6  μM for HL60 cells) with a weak Prolyl oligopeptidase (POP) inhibitory activity.

For research use only. We do not sell to patients.

Pyrrocidine B

Pyrrocidine B Chemical Structure

CAS No. : 428439-25-2

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Pyrrocidine B Related Antibodies

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Description

Pyrrocidine B (Compound 6), an alkaloid, is a microbial secondary metabolite. Pyrrocidine B can be isolated from the endophytic fungus Neonectria ramulariae Wollenw KS-246. Pyrrocidine B has significant cytotoxicity against leukemia cells (IC50 of 4.6  μM for HL60 cells) with a weak Prolyl oligopeptidase (POP) inhibitory activity[1].

Molecular Weight

489.65

Formula

C31H39NO4
CAS No.
SMILES

C[C@]1(C[C@@H]2C)[C@](C(C)=C3)([H])[C@]([C@](C([C@](C(N4)=O)([H])C[C@@]4(C5)O)=O)([H])[C@@H]3C=C)([H])[C@@](OC6=CC=C5C=C6)([H])[C@]1([H])[C@H](C2)C
Structure Classification
Initial Source

Neonectria ramulariae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pyrrocidine B Related Classifications

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Keywords:

Pyrrocidine B428439-25-2Endogenous MetaboliteProlyl Endopeptidase (PREP)prolyl oligopeptidasePOPMicrobialSecondary metaboliteAlkaloidNeonectria ramulariae Wollenw KS-246HL60 cellsInhibitorinhibitorinhibit

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