2. Metabolic Enzyme/Protease Anti-infection
  3. Endogenous Metabolite Fungal
  4. Neosartoricin

Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence.

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Neosartoricin

Neosartoricin Chemical Structure

CAS No. : 1421941-29-8

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Neosartoricin Related Antibodies

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Description

Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence[1][2].

Molecular Weight

484.50

Formula

C26H28O9
CAS No.
SMILES

OC1=C2C(C[C@](O)([C@@H](C2=O)OC(C)=O)CC(/C=C(O)/C)=O)=C(C3=CC(O)=CC(O)=C31)C/C=C(C)\C
Structure Classification
Initial Source

Aspergillus fumigatus
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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Neosartoricin Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neosartoricin1421941-29-8FumicyclineEndogenous MetaboliteFungalMicrobialSecondary metaboliteNeosartorya fischeriAspergillus fumigatusA549 cellsRAW 264.7 cellsImmunosuppressiveFungal defenseInhibitorinhibitorinhibit

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