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MXC 017

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174212
    MXC-017

    		Apoptosis
    MXC-017 is a BBB-penetrable and ureabased compound, directly targeting glioma stem cells (GSCs). MXC-017 prevents radiation-induced GSC formation but increases G0/G1 arrest and apoptosis. MXC-017 has minimal off-target effects with no significant cell toxicity up to 10 µM. MXC-017 significantly extends median survival in patient-derived orthotopic xenograft (PDOX) glioblastoma (GBM) mice models with combination of radiation .
    MXC-017

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