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MP 1

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By Targets:	Bacterial (1) c-Fms (1) Hippo (MST) (1) Mixed Lineage Kinase (1) PROTACs (1)
By Research Areas:	Cancer (4) Infection (2) Inflammation/Immunology (1)

5

Inhibitors & Agonists

1

Peptides

1

Inhibitory Antibodies

1

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Polybia-MP1	Bacterial	Infection
Polybia-MP1 is an antimicrobial mastoparan peptide .

*Anti-Mouse GM-CSF Antibody (MP1-22E9)*	c-Fms	Infection Inflammation/Immunology Cancer
Anti-Mouse GM-CSF Antibody (MP1-22E9) is a rat-derived anti-mouse GM-CSF IgG2a antibody inhibitor. Anti-Mouse GM-CSF Antibody (MP1-22E9) can neutralize GM-CSF. Anti-Mouse GM-CSF Antibody (MP1-22E9) can be used for the researches of cancer, infection inflammation and immunology, such as cholangiocarcinoma and arthritis .

XMU-MP-1 70+ Cited Publications	Hippo (MST)	Cancer
XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC₅₀s of 71.1 and 38.1 nM, respectively .

*MP-1*	Others	Cancer
MP-1 is an anti-cancer agent. MP-1 exhibits strong toxicity in UOK262 cells (CC₅₀ ≈ 30 µM) deficient in fumarate hydratase (FH). MP-1 can be used for cancer research .

PROTAC MLKL Degrader-2	PROTACs Mixed Lineage Kinase	Cancer
PROTAC MLKL Degrader-2 (compound MP-1) is a PROTAC targeting MLKL (Mixed Lineage Kinase). PROTAC MLKL Degrader-2 is composed of PROTAC target protein ligand PROTAC MLKL Degrader-2 (HY-169072) (red part), E3 ligase ligand Thalidomide (HY-14658) (blue part) and PROTAC Linker N-Methylpiperazine (HY-78871) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-N-methylpiperazine (HY-169074) ^{[1] ^.}

Cat. No.	Product Name	Target	Research Area

*Anti-Mouse GM-CSF Antibody (MP1-22E9)*	c-Fms	Infection Inflammation/Immunology Cancer
Anti-Mouse GM-CSF Antibody (MP1-22E9) is a rat-derived anti-mouse GM-CSF IgG2a antibody inhibitor. Anti-Mouse GM-CSF Antibody (MP1-22E9) can neutralize GM-CSF. Anti-Mouse GM-CSF Antibody (MP1-22E9) can be used for the researches of cancer, infection inflammation and immunology, such as cholangiocarcinoma and arthritis .

Cat. No.	Compare	Product Name	Species	Source

	MAPKSP1 Protein, Human (His) Ragulator CoMPlex Protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; MP1; Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; Mitogen-Activated Protein Kinase Scaffold Protein 1; LAMTOR3; MAP2K1IP	Human	E. coli
	The MAPKSP1 protein, also known as porphobilinogen deaminase (HMBS), is crucial in the heme biosynthetic pathway and catalyzes the sequential polymerization of four porphobilinogen molecules to form hydroxymethyl bixane. The process begins with the assembly of the dipyrromethane cofactor of porphobilinogen or preuroporphyrinogen. MAPKSP1 Protein, Human (His) is the recombinant human-derived MAPKSP1 protein, expressed by E. coli , with N-6*His labeled tag.

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