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Results for "

ML 3000

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1452
    Licofelone
    1 Publications Verification

    ML-3000

    		 COX Lipoxygenase Apoptosis Inflammation/Immunology Cancer
    Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins .
    Licofelone
  • HY-41982
    D-Glucuronic acid lactone
    1 Publications Verification

    D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone

    		 Endogenous Metabolite Drug Derivative Cardiovascular Disease Metabolic Disease
    D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .
    D-Glucuronic acid lactone
  • HY-B1452S1
    Licofelone-d6

    ML-3000-d6

    		 Apoptosis Lipoxygenase COX Cancer
    Licofelone-d6 is the deuterium labeled Licofelone . Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins .
    Licofelone-d6

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