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Results for "

MAPKAP1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Natural
Products

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS28527
    Mapkap1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Mapkap1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapkap1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Mapkap1 Rat Pre-designed siRNA Set A
    Mapkap1 Rat Pre-designed siRNA Set A
  • HY-RS22009
    Mapkap1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Mapkap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapkap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Mapkap1 Mouse Pre-designed siRNA Set A
    Mapkap1 Mouse Pre-designed siRNA Set A
  • HY-RS08130
    MAPKAP1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MAPKAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPKAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MAPKAP1 Human Pre-designed siRNA Set A
    MAPKAP1 Human Pre-designed siRNA Set A
  • HY-N1190
    DL-Syringaresinol

    (±)-Syringaresinol

    		 p38 MAPK AP-1 Bacterial Infection
    DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv [1] .
    DL-Syringaresinol
  • HY-N1326
    Santamarine

    Santamarin; Balchanin

    		 Keap1-Nrf2 Inflammation/Immunology
    Santamarine (Santamarin), a sesquiterpene lactone, increases HO-1 expression through Nrf2 translocation and suppresses NO, PGE2, TNF-α, and IL-1β production through inhibition of NF-κB translocation in LPS-induced macrophages. Santamarine shows anti-photoaging properties via inhibition of MAPK/AP-1 and stimulation of TGF-β/Smad signaling in UVA-irradiated human dermal fibroblasts (HDFs). Antioxidant activities [1] .
    Santamarine
  • HY-176166
    PD-M6

    		mTOR PROTACs Cancer
    PD-M6 is an mTOR PROTAC degrader (DC50: 4.8 μM). PD-M6 promotes the ubiquitination and degradation of mTOR. PD-M6 inhibits the proliferation of HeLa, MCF-7, and HepG2 cancer cell lines (IC50 values of 11.3, 2.58, and 3.23 μM, respectively) and induces autophagy. PD-M6 specifically induces the degradation of LAMTOR1, a key protein in the mTOR signaling pathway. (Pink: target protein mTOR ligand (HY-B0795); target protein mTOR ligand activity control (HY-W150930); black: linker (HY-W008296); blue: E3 ligase CRBN ligand (HY-41547); target protein ligand activity control + linker (HY-176167)) [1].
    PD-M6

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