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Results for "

Ki67

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Apoptosis (5) Bcl-2 Family (1) c-Met/HGFR (1) Caspase (1) CDK (1) DNA/RNA Synthesis (7) EGFR (1) Endogenous Metabolite (2) ERK (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (1) Histone Methyltransferase (1) IFNAR (1) Interleukin Related (1) Lipoxygenase (1) MMP (1) mTOR (1) PI3K (2) Reference Standards (1) Small Interfering RNA (siRNA) (1) Src (1) Syk (1) TAM Receptor (1) TNF Receptor (1) VEGFR (3)
By Research Areas:	Cancer (8) Endocrinology (2) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) siRNAs (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1941

4-tert-Octylphenol 1 Publications Verification	Endogenous Metabolite Apoptosis DNA/RNA Synthesis	Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-150082

CP681301	CDK DNA/RNA Synthesis	Cancer
CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila .

HY-162382

KTC1101	PI3K Akt mTOR	Cancer
KTC1101 is an orally active pan-PI3K inhibitor. KTC1101 can inhibit the PI3K signaling pathway, reduce downstream AKT and mTOR phosphorylation, and reduces the expression of *Ki67*. The anti-tumor effect of KTC1101 has a dual mechanism of action: directly inhibiting tumor cell growth and dynamically enhancing immune response .

HY-155243

12R-LOX-IN-1	DNA/RNA Synthesis	Inflammation/Immunology
12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC₅₀: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research .

HY-P991408

DLX-105	TNF Receptor Interleukin Related IFNAR	Inflammation/Immunology
DLX-105 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. DLX-105 reduces skin epidermal thickness and the expression of K16 and Ki67. DLX-105 down-regulates the mRNA levels of IL-17, TNF-α, IL-23p19, IL-12p40, and IFN-γ. DLX-105 can be used in psoriasis research .

HY-P991419

MSB-0254	VEGFR	Cancer
MSB-0254 is a human monoclonal antibody (mAb) targeting VEGFR2/KDR/CD309. MSB-0254 inhibits the invasion, migration, and vascular mimetic (VM) formation of U251 and primary glioma cells. MSB-0254 inhibits the growth of U251 and GL261 cell transplanted tumors. MSB-0254 reduces the expression of CD34, VEGFR2, Ki67, MMP2, MMP9, and CD34/PAS. MSB-0254 can be used in advanced solid tumors research .

HY-156872

MTX-216	PI3K EGFR Syk Apoptosis	Cancer
MTX-216 is a dual ATP-competitive inhibitor of PI3K and EGFR. MTX-216 cosuppresses Ki-67 and ribosomal S6 phosphorylation and induces apoptosis in NF1 ^LOF cells. MTX-216 suppresses the activity of SYK kinase, with an IC₅₀ of 281 nM. MTX-216 is used in the research of Melanoma .

HY-169265

BRD-K20733377	Bcl-2 Family	Others
BRD-K20733377 is an inhibitor for Bcl-2, and exhibits selective cytotoxicity against senescent cells, that inhibits the viability of Etoposide (HY-13629)-induced IMR-90 senescent cell with an IC₅₀ of 10.7 μM. BRD-K20733377 reduces the mRNA expression of aging-related genes p16, p21 and KI67 in aged mouse model .

HY-B1941R

4-tert-Octylphenol (Standard)	Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis	Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
4-tert-Octylphenol (Standard) is the analytical standard of 4-tert-Octylphenol. This product is intended for research and analytical applications. 4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-P991664

AG01	Src Akt ERK TAM Receptor c-Met/HGFR MMP HIF/HIF Prolyl-Hydroxylase VEGFR	Cancer
AG01 is a monoclonal antibody against progranulin (GP88). AG01 inhibits triple-negative breast cancer (TNBC) cell proliferation and migration, reduces the expression of phosphorylated protein kinases p-Src, p-AKT, and p-ERK, and reduces the expression of oncogenic proteins such as Axl, c-MET, HIF-1α, and VEGF. AG01 inhibits tumor growth and Ki67 expression in a TNBC xenograft mouse model. AG01 can be used in the research of TNBC and other cancers .

HY-156077

anti-TNBC agent-2	Apoptosis DNA/RNA Synthesis	Cancer
anti-TNBC agent-2 (3j) an anti-Triple negative breast cancer (TNBC) purine derivative. anti-TNBC agent-2 induces MDA-MB-231 cells apoptosis, and inhibits its migration and angiogenesis. anti-TNBC agent-2 inhibits tumor growth and metastasis and reduces the expression of Ki67 and CD31 protein in TNBC xenograft models. anti-TNBC agent-2 can be used for Triple negative breast cancer (TNBC) research .

HY-155244

12R-LOX-IN-2	Lipoxygenase DNA/RNA Synthesis	Inflammation/Immunology
12R-LOX-IN-2 (compound 7b) is an inhibitor of 12R-lipoxygenase (12R-LOX). 12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and suppresses colony formation. 12R-LOX-IN-2 also reduced the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 can be used in research into psoriasis and other skin-related inflammatory diseases .

HY-156096

HDAC3-IN-2	HDAC Histone Methyltransferase Caspase Apoptosis DNA/RNA Synthesis	Cancer
HDAC3-IN-2 (compound 4i) is a pyrazinyl hydrazide-based HDAC3 inhibitor (IC₅₀: 14 nM) that efficiently targets triple-negative breast cancer cells. HDAC3-IN-2 is cytotoxic with an IC₅₀ of 0.55 μM against 4T1 and an IC₅₀ of 0.74 μM against MDA-MB-231. HDAC3-IN-2 has anti-tumor efficacy in vivo in tumor-bearing mouse models, selectively increasing the acetylation levels of H3K9, H3K27 and H4K12, increasing the contents of apoptosis-related caspase-3, caspase-7 and cytochrome c, and reducing Proliferation-related Bcl-2, CD44, EGFR, and Ki-67 levels .

HY-117991

DW10075	VEGFR	Cancer
DW10075 is a highly selective and orally active VEGFR inhibitor targeting the VEGF/VEGFR pathway. DW10075 selectively inhibits VEGFR-1, VEGFR-2, and VEGFR-3, but has no effect on FGFR and PDGFR. DW10075 inhibits VEGF-induced HUVEC proliferation, migration, and tube formation. And DW10075 inhibits angiogenesis in both the rat aortic ring model and the chick chorionic membrane model. DW10075 also exhibits antiproliferative activity against human cancer cell lines, with IC₅₀s of 2.2 μM and 22.2 μM against U87-MG human glioblastoma cells and A375 melanoma cells, respectively. In the nude mouse U87-MG xenograft tumor model, DW10075 (po) significantly inhibits tumor growth and reduces the expression of CD31 and Ki67 in tumor tissues.

HY-RS21649

Mki67 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mki67 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mki67 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mki67 Mouse Pre-designed siRNA Set A Mki67 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P991408

DLX-105	TNF Receptor Interleukin Related IFNAR	Inflammation/Immunology
DLX-105 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. DLX-105 reduces skin epidermal thickness and the expression of K16 and Ki67. DLX-105 down-regulates the mRNA levels of IL-17, TNF-α, IL-23p19, IL-12p40, and IFN-γ. DLX-105 can be used in psoriasis research .

HY-P991419

MSB-0254	VEGFR	Cancer
MSB-0254 is a human monoclonal antibody (mAb) targeting VEGFR2/KDR/CD309. MSB-0254 inhibits the invasion, migration, and vascular mimetic (VM) formation of U251 and primary glioma cells. MSB-0254 inhibits the growth of U251 and GL261 cell transplanted tumors. MSB-0254 reduces the expression of CD34, VEGFR2, Ki67, MMP2, MMP9, and CD34/PAS. MSB-0254 can be used in advanced solid tumors research .

HY-P991664

AG01	Src Akt ERK TAM Receptor c-Met/HGFR MMP HIF/HIF Prolyl-Hydroxylase VEGFR	Cancer
AG01 is a monoclonal antibody against progranulin (GP88). AG01 inhibits triple-negative breast cancer (TNBC) cell proliferation and migration, reduces the expression of phosphorylated protein kinases p-Src, p-AKT, and p-ERK, and reduces the expression of oncogenic proteins such as Axl, c-MET, HIF-1α, and VEGF. AG01 inhibits tumor growth and Ki67 expression in a TNBC xenograft mouse model. AG01 can be used in the research of TNBC and other cancers .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1941

4-tert-Octylphenol 1 Publications Verification	Monophenols Neurological Disease Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite Apoptosis DNA/RNA Synthesis
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-B1941R

4-tert-Octylphenol (Standard)	Monophenols Source classification Phenols Endogenous metabolite	Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis
4-tert-Octylphenol (Standard) is the analytical standard of 4-tert-Octylphenol. This product is intended for research and analytical applications. 4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

Species:	Human (2)
Tag:	His (1) GST (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72508

	Ki67/MKI67 Protein, Human (GST) Antigen Ki-67; Ki-67; KiA; MIB-1; MKi67; Proliferation Marker Protein Ki-67	Human	E. coli
	Ki67/MKI67 is localized on mitotic chromosomes and maintains its dispersion during nuclear envelope disassembly. It covers a large portion of the chromosome surface and prevents chromatin from collapsing into clumps. Ki67/MKI67 Protein, Human (GST) is the recombinant human-derived Ki67/MKI67 protein, expressed by E. coli , with N-GST labeled tag.

HY-P700257

	Ki67/MKI67 Protein, Human (His) Proliferation marker protein Ki-67; Antigen identified by monoclonal antibody Ki-67 (Antigen Ki-67; Antigen Ki67); MKi67	Human	E. coli
	Ki67/MKI67 is localized on mitotic chromosomes and maintains its dispersion during nuclear envelope disassembly. It covers a large portion of the chromosome surface and prevents chromatin from collapsing into clumps. Ki67/MKI67 Protein, Human (His) is the recombinant mouse-derived Ki-67(MKI67) protein, expressed by E. coli , with N-6*His labeled tag.

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HY-P81234

	Ki67 Antibody 2 Publications Verification Antigen identified by monoclonal antibody Ki 67; Antigen Ki67; KiA; Ki67; MKi67; Proliferation related Ki 67 antigen; Antigen Ki-67; Ki67_MOUSE.	IHC-P, IHC-F, ICC/IF	Human
	Ki67 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Ki67.

HY-P80734

	Ki67 Antibody (YA001) MKi67; Antigen Ki-67	IHC-P, ICC/IF	Human, Mouse
	Ki67 Antibody (YA001) is a Rat-derived and non-conjugated IgG2b monoclonal antibody, targeting to Ki67.

HY-P84338

	Ki67 Antibody (YA4035) KiA; Ki-67; MKi67	WB, IHC-P, FC, ELISA, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	Ki67 Antibody (YA4035) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ki67.

HY-P80505

	Ki67 Antibody (YA717) 1 Publications Verification	IHC-P	Human, Mouse
	Ki67 Antibody (YA717) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ki67.

HY-P80506

	Ki67 Antibody (YA322) 2 Publications Verification	IHC-P, IHC-F, ICC/IF, FC	Human, Mouse, Rat
	Ki67 Antibody (YA322) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ki67.

HY-P86608

	Ki67 Antibody (YA6300) MKi67; Antigen Ki-67	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Ki67 Antibody (YA6300) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ki67.

HY-P85659

	Ki67 Antibody (YA5351) Antigen identified by monoclonal Ki 67; Antigen identified by monoclonal Ki-67; Antigen Ki-67; Antigen Ki67; Antigen Ki67; Ki67_HUMAN; KiA; Marker of prolifeRation Ki-67; MIB 1; MIB; MKi67; PPP1R105; ProlifeRation marker protein Ki-67; ProlifeRation related Ki 67 antigen; Protein phosphatase 1 regulatory subunit 105; RP11-380J17.2	IHC-P, WB, ICC/IF, ELISA	Human
	Ki67 Antibody (YA5351) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Ki67.

HY-P86061

	Ki67 Antibody (YA5753) Antigen identified by monoclonal Ki 67; Antigen identified by monoclonal Ki-67; Antigen Ki-67; Antigen Ki67; Antigen Ki67; Ki67_HUMAN; KiA; Marker of prolifeRation Ki-67; MIB 1; MIB; MKi67; PPP1R105; ProlifeRation marker protein Ki-67; ProlifeRation related Ki 67 antigen; Protein phosphatase 1 regulatory subunit 105; RP11-380J17.2	IHC-P, WB, ELISA	Human
	Ki67 Antibody (YA5753) is a Rabbit-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ki67.

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HY-RS21649

Mki67 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Mki67 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mki67 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Ki67

Inhibitors & Agonists

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Antibodies

Oligonucleotides

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