Search Result
Results for "
Imaging Agent
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-139579
-
OTL 38
|
Fluorescent Dye
|
Cancer
|
Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm .
|
-
-
- HY-D1063
-
|
Fluorescent Dye
|
Cancer
|
IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging .
|
-
-
- HY-D1041
-
ICG NHS ester
|
Fluorescent Dye
|
Cancer
|
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
-
- HY-P10023
-
|
Biochemical Assay Reagents
|
Cancer
|
Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring .
|
-
-
- HY-156982
-
|
Others
|
Cancer
|
Parpi is a PET radioactive tracer with low lipotropy. Parpi can be used as a tumor imaging agent .
|
-
-
- HY-159500A
-
-
-
- HY-148155
-
-
-
- HY-145385
-
|
Fluorescent Dye
|
Others
|
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca 2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .
|
-
-
- HY-163545
-
|
Drug Derivative
|
Cancer
|
Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues .
|
-
-
- HY-164766
-
|
Fluorescent Dye
|
Infection
|
ICG-DBCO-1-Maltotriose is a specific imaging agent for detecting bacterial infections. ICG-DBCO-1-Maltotriose is composed of the fluorescent dye Indocyanine green (ICG) (HY-D0711) and a maltotriose sugar .
|
-
-
- HY-D1716
-
|
Fluorescent Dye
Drug Intermediate
|
Cancer
|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
|
-
-
- HY-B0594
-
Iohexol
3 Publications Verification
|
Autophagy
Mitophagy
|
Cancer
|
Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
|
-
-
- HY-B0594R
-
|
Autophagy
Mitophagy
|
Cancer
|
Iohexol (Standard) is the analytical standard of Iohexol. This product is intended for research and analytical applications. Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
|
-
-
- HY-158251
-
|
Others
|
Cancer
|
BIBD-300 is a PARP-1 imaging agent with high affinity for PARP-1. BIBD-300 can accurately localize C6 and U87MG tumors, which can be used for research in the diagnosis of breast cancer, prostate cancer, glioma, and liver cancer .
|
-
-
- HY-D2378
-
-
-
- HY-159841
-
-
-
- HY-P10590
-
|
Fluorescent Dye
|
Cancer
|
Talogreptide mesaroxetan is a diagnostic imaging agent, with antineoplastic effect .
|
-
-
- HY-W034551
-
|
Radionuclide-Drug Conjugates (RDCs)
|
Others
Cancer
|
DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging .
|
-
-
- HY-159500
-
-
-
- HY-159526
-
-
-
- HY-A0266
-
-
-
- HY-B1292
-
Adipiodone
|
Drug Derivative
|
Others
|
Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging.
|
-
-
- HY-P1043A
-
|
Aminopeptidase
|
Cancer
|
NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging .
|
-
-
- HY-P1043
-
|
Aminopeptidase
|
Cancer
|
NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging .
|
-
-
- HY-D1423
-
|
Fluorescent Dye
|
Others
|
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .
|
-
-
- HY-136213
-
|
Fluorescent Dye
|
Others
|
Endoplasmic reticulum dye 1 is a promising live cell imaging agent for the detection of exocytotic events at the plasma membrane. Endoplasmic reticulum dye 1 shows low cytotoxicity, resistance to photobleaching , which is ideal for imaging either short- or long-time courses .
|
-
-
- HY-P10157
-
|
Biochemical Assay Reagents
|
Others
|
ARF(1-22) is potentially capable of intracellular penetration to deliver small molecules, proteins, imaging agents, and pharmaceutical nanocarriers .
|
-
-
- HY-168976
-
|
Biochemical Assay Reagents
|
Others
|
Gadosircoclamide can be used as a a magnetic resonance imaging agent with high relaxivity, good stability and safety, and can be used for the diagnosis of various diseases .
|
-
-
- HY-147151
-
|
Biochemical Assay Reagents
|
Others
|
AMCPy is a potent electron paramagnetic resonance (EPR) brain imaging agent, possessing excellent lipophilicity for blood brain barrier (BBB) penetration .
|
-
-
- HY-109153
-
|
Biochemical Assay Reagents
|
Others
|
Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging .
|
-
-
- HY-157977
-
-
-
- HY-173384
-
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
|
Biochemical Assay Reagents
|
Neurological Disease
Inflammation/Immunology
Cancer
|
DSPE-DOTA sodium (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt) is a chelating lipid used as a key contrast agent in magnetic resonance imaging (MRI). DSPE-DOTA sodium can be used for imaging detection of tumors, neurological and inflammatory diseases .
|
-
-
- HY-170749
-
|
Drug Intermediate
|
Others
|
DFO-BCN is a drug intermediate, that can be used for synthesis of PET/CT imaging agent DFO-CPC634 through click chemistry .
|
-
-
- HY-W153917
-
|
Biochemical Assay Reagents
|
|
Diatrizoic acid EP impurity A is an organic compound with potential effects on biological systems and specific pharmacological activities. Diatrizoic acid EP impurity A can be used as a contrast agent in imaging examinations to enhance the clarity of images such as X-rays and CT scans. Diatrizoic acid EP impurity A has also been studied for the separation and analysis of compounds.
|
-
-
- HY-137006
-
|
Biochemical Assay Reagents
|
Others
|
MTT Formazan is a contrast agent used in photoacoustic microscopy to enhance the imaging of living cells, especially in 3D cell culture and tissue engineering applications .
|
-
-
- HY-135423
-
Dy-DTPA-BMA
|
Biochemical Assay Reagents
|
Others
|
Sprodiamide (Dy-DTPA-BMA) is a susceptibility-based MRI contrast agent that can be used to visualize image intensity changes during vascular transport of drugs .
|
-
-
- HY-108760
-
Gd-DOTA; Magnescope; P-449
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Others
Neurological Disease
|
Gadoterate meglumine (Gd-DOTA) is a non-specific paramagnetic gadolinium complex used as a contrast enhancer in magnetic resonance imaging (MRI). Gadoterate meglumine, as a contrast agent in MRI, is able to shorten the longitudinal relaxation time (T1) of tissue, resulting in a brighter signal in MRI images. Gadoterate meglumine can be used for the study of the central nervous system (such as the brain and spinal cord), abdominal, pelvic organs, breast, bone and joint imaging, angiography, and cardiac electrophysiology .
|
-
-
- HY-161981
-
|
Apoptosis
|
Cancer
|
Antitumor agent-187 (compound I3) is a photosensitizer based on 5,15-diaryltetrabenzoporphyrin with a maximum absorption wavelength of ~668 nm and anticancer activity. Antitumor agent-187 can induce apoptosis and can be used in photodynamic therapy (PDP). Antitumor agent-187 selectively accumulates at tumor sites and has real-time fluorescence imaging capabilities .
|
-
-
- HY-B0926A
-
Diatrizoic acid sodium salt; Sodium amidotrizoate
|
Apoptosis
|
Inflammation/Immunology
|
Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
|
-
-
- HY-169732
-
|
Biochemical Assay Reagents
|
Others
|
Gadoquatrane is a highly stable gadolinium-based MRI contrast agent that enhances soft tissue imaging by altering the local magnetic field, with low permeability and high biological safety .
|
-
-
- HY-111513
-
|
Amyloid-β
|
Neurological Disease
|
4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid-β (1-40) with a KD of 1.7 nM.
|
-
-
- HY-B1292R
-
|
Drug Derivative
|
Others
|
Iodipamide (Standard) is the analytical standard of Iodipamide. This product is intended for research and analytical applications. Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging.
|
-
-
- HY-B0926
-
Diatrizoate; Amidotrizoic acid
|
Apoptosis
|
Inflammation/Immunology
|
Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
|
-
-
- HY-B0594S
-
|
Isotope-Labeled Compounds
Autophagy
Mitophagy
|
Cancer
|
Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].
|
-
-
- HY-128890
-
|
ADC Linker
|
Cancer
|
DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors .
|
-
-
- HY-P10012
-
GYK-DTPA
|
Biochemical Assay Reagents
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma . Pendetide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
|
-
-
- HY-129650
-
AV-45
|
Biochemical Assay Reagents
|
Others
|
Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 .
|
-
-
- HY-P10911
-
|
LDLR
|
Others
|
IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM and can be used for drug- and imaging agents delivery across the blood-labyrinth barrier (BLB) .
|
-
-
- HY-47176
-
|
Fluorescent Dye
|
Others
|
QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core .
|
-
-
- HY-136201
-
|
Biochemical Assay Reagents
|
Cancer
|
Sodium Glucoheptonate is used as a kit for radio-labeling with Tc-99m. Tc-99m glucoheptonate is kidney- and brain-imaging agent, and can be used in brain-tumor detection .
|
-
- HY-P99289
-
Antibody hLL 2
|
CD22
|
Inflammation/Immunology
Cancer
|
Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases .
|
-
- HY-147865
-
|
Galectin
Apoptosis
|
Cancer
|
Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent .
|
-
- HY-113719
-
|
Carbonic Anhydrase
|
Cancer
|
VM4-037 can be used for the synthesis of VM4-037(18F). VM4-037(18F) is a fluorinated PET imaging agent for carbonic anhydrase IX .
|
-
- HY-155485
-
|
Others
|
Cancer
|
Abi-DZ-1 is a potential multifunctional theranostic agent via the HIF1α/OATPs Pathway. Abi-DZ-1 can be used in the research of tumor-targeted imaging and precision therapy .
|
-
- HY-D1443
-
(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
|
Amyloid-β
|
Others
|
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .
|
-
- HY-D2335
-
|
Fluorescent Dye
|
Neurological Disease
|
SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems .
|
-
- HY-129650R
-
AV-45 (Standard)
|
Biochemical Assay Reagents
|
Others
|
Flobetapir (Standard) (AV-45 (Standard)) is the analytical standard of Flobetapir (HY-129650). This product is intended for research and analytical applications. Flobetapirmay is a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound.
|
-
- HY-172205
-
|
Cytochrome P450
|
Cancer
|
CHL2310 is the inhibitor for CYP46A1 with an IC50 of 0.11 nM, and a Kd of 0.37 nM. CHL2310 can cross blood-brain barrier. CHL2310 can be used as a PET imaging agent, when labeled with radioactive 18F .
|
-
- HY-120115
-
Olaparib-bodipy FL
|
PARP
Fluorescent Dye
|
Cancer
|
PARPi-FL (Olaparib-bodipy FL) is a small-molecule fluorescent inhibitor of PARP1 that can specifically bind to PARP1. PARPi-FL can be used as a fluorescent imaging agent for tumor detection, diagnosis, and surgical guidance .
|
-
- HY-106586
-
P-286
|
Biochemical Assay Reagents
|
Others
|
Ioxaglic acid (P-286) is negatively charged contrast agent, is useful as an inverse indicator for glycosaminoglycan (GAG) used in computed tomography (CT). Ioxaglic acid can be used for imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content .
|
-
- HY-148465
-
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution .
|
-
- HY-B0926R
-
Diatrizoate (Standard); Amidotrizoic acid (Standard)
|
Apoptosis
|
Inflammation/Immunology
|
Diatrizoic acid (Standard) is the analytical standard of Diatrizoic acid. This product is intended for research and analytical applications. Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
|
-
- HY-B0926AR
-
|
Apoptosis
|
Inflammation/Immunology
|
Sodium diatrizoate (Standard) is the analytical standard of Sodium diatrizoate. This product is intended for research and analytical applications. Sodium diatrizoate (Diatrizoic acid sodium salt) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Sodium diatrizoate induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium .
|
-
- HY-173383
-
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
|
Biochemical Assay Reagents
|
Inflammation/Immunology
Cancer
|
DOPE-DOTA sodium is a chelated lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). DOPE-DOTA sodium can be used for cancer, blood-brain barrier disruption, abnormalities such as aneurysms or plaque buildup, inflammation in arthritis, and liver function and lesions study
|
-
- HY-W012634
-
|
Bacterial
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent [1][2][3][4].
|
-
- HY-106594A
-
Iron(III) ferrocyanide; Milori blue
|
Bacterial
|
Infection
Cancer
|
Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
|
-
- HY-106594B
-
Pigment blue 27
|
Bacterial
|
Infection
Cancer
|
Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
|
-
- HY-101185
-
|
Tau Protein
|
Neurological Disease
|
T808 is a tau-selective Alzheimer’s PET ligand. T808 is a type of imaging agent used in positron emission tomography (PET) scans. It is a radiotracer that is used to help visualize certain areas of the body, such as the brain, in order to diagnose and monitor various medical conditions .
|
-
- HY-109513
-
Ioxilan
1 Publications Verification
|
Biochemical Assay Reagents
|
Others
|
Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
|
-
- HY-D1450
-
S01448
|
Fluorescent Dye
|
Cancer
|
IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
|
-
- HY-172367
-
|
Fluorescent Dye
|
Cancer
|
Tc-BQ0413 exhibits binds specifically to prostate-specific membrane antigen (PSMA) with good affinity. Tc-BQ0413 can be used as a single-photon emission computed tomography (SPECT) imaging agent, when labeled with technetium-99m .
|
-
- HY-P10557
-
|
Biochemical Assay Reagents
|
Neurological Disease
|
DAG peptide is a cyclic peptide. DAG peptide selectively recognizes a subset of astrocytes that are activated in Alzheimer's disease (AD) starting at an early stage of the disease. DAG peptide can be used as a tool to enhance the delivery of therapeutics and imaging agents to sites of vascular changes and astrogliosis in diseases associated with neuroinflammation .
|
-
- HY-150970
-
|
Pyroptosis
|
Cancer
|
ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm,λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway .
|
-
- HY-172366
-
|
PSMA
|
Cancer
|
BQ0413 exhibits good affinity to PSMA with a KD of 89 pM. BQ0413 exhibits good uptake and internalization property with an internalization rate of 44% in PC3-pip cell. BQ0413 can be used as tumor imaging agent when labeled with 99mTc .
|
-
- HY-W338446
-
|
Tau Protein
|
Neurological Disease
|
BF-170 is a selective tau fibril binding agent with an EC50 of 221 nM. It exhibits good blood-brain barrier permeability, and after intravenous injection in mice, the concentration in brain tissue reaches 9.1% ID/g within 2 minutes (with a brain clearance rate of 0.25% ID/g after 30 minutes). BF-170 can be used as a probe for tau protein pathology imaging in Alzheimer's disease (AD). It plays an important role in early-stage AD research and holds potential for imaging studies of tau-related neurodegenerative diseases .
|
-
- HY-W440919
-
|
Liposome
|
Others
|
DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-136201R
-
|
Biochemical Assay Reagents
|
Cancer
|
Sodium Glucoheptonate (Standard) is the analytical standard of Sodium Glucoheptonate. This product is intended for research and analytical applications. Sodium Glucoheptonate is used as a kit for radio-labeling with Tc-99m. Tc-99m glucoheptonate is kidney- and brain-imaging agent, and can be used in brain-tumor detection[1][2].
|
-
- HY-A0168A
-
CVT-3146 hydrate
|
Adenosine Receptor
|
Cardiovascular Disease
|
Regadenoson hydrate (NSC 169186) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson hydrate also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
|
-
- HY-A0168
-
CVT-3146
|
Adenosine Receptor
|
Cardiovascular Disease
Cancer
|
Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
|
-
- HY-164981
-
|
Drug Intermediate
|
Cancer
|
p-SCN-Bn-DOTA(tBu)4 is the derivative of DOTA (HY-W053583). p-SCN-Bn-DOTA(tBu)4 is the component of the Gd(III)-DOTA-IAC, which is a targeted magnetic resonance imaging (MRI) contrast agent for αvβ3 integrin receptor .
|
-
- HY-W112239
-
|
Reactive Oxygen Species
Fluorescent Dye
|
Cancer
|
BDPI is the a BODIPY derivative. BDPI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 µg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models .
|
-
- HY-109513R
-
|
Biochemical Assay Reagents
|
Others
|
Ioxilan (Standard) is the analytical standard of Ioxilan. This product is intended for research and analytical applications. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
|
-
- HY-W012634R
-
|
Bacterial
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .
|
-
- HY-B1684
-
SQ 26962
|
Biochemical Assay Reagents
|
Others
|
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .
|
-
- HY-106586A
-
P-286 sodium
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
Ioxaglate sodium (P-286 sodium) is an ionic, dimeric diagnostic contrast agent whose activity is mainly reflected in its ability to provide sufficient X-ray absorption to enhance visualization of blood vessels and other structures during imaging. Ioxaglate sodium is used to study the anatomical structure and functional status of cardiac vessels, especially in the diagnosis of coronary artery disease .
|
-
- HY-117756
-
DCFPYL
|
PSMA
|
Others
Cancer
|
Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA) .
|
-
- HY-141464
-
Fmoc-Asn(Ac3AcNH-beta-Glc)-OH
|
Amino Acid Derivatives
|
Cancer
|
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .
|
-
- HY-P10369
-
-
- HY-D1274
-
|
Fluorescent Dye
|
Inflammation/Immunology
|
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1274B
-
|
Fluorescent Dye
|
Inflammation/Immunology
|
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-136886
-
IR-820
1 Publications Verification
New Indocyanine Green
|
Fluorescent Dye
|
Cancer
|
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
|
-
- HY-158125
-
|
PSMA
|
Cancer
|
PSMA binder-2 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-D1274A
-
|
Fluorescent Dye
|
Others
|
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-A0168R
-
|
Adenosine Receptor
|
Cardiovascular Disease
|
Regadenoson (Standard) is the analytical standard of Regadenoson. This product is intended for research and analytical applications. Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
|
-
- HY-P10792
-
|
EGFR
|
Cancer
|
HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
|
-
- HY-W009310R
-
|
Endogenous Metabolite
Organoid
|
Others
|
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .
|
-
- HY-B1684R
-
|
Biochemical Assay Reagents
|
Others
|
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .
|
-
- HY-153127
-
AV-133
|
Biochemical Assay Reagents
|
Neurological Disease
|
Florbenazine (AV-133) is a diagnostic imaging agent targeting the central nervous system monoamine transporter VMAT2, and its F-18 labeled form can be used for PET scanning. The biodistribution of [18F]Florbenazine in mice shows a high striatum/cerebellum ratio (0.48), which can be used for the diagnostic research of neurodegenerative diseases (including dementia with Lewy bodies and Parkinson's disease) .
|
-
- HY-P10913
-
|
Bacterial
|
Infection
|
HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .
|
-
- HY-16219
-
Gd-EOB-DTPA disodium; ZK 139834
|
Biochemical Assay Reagents
|
Cancer
|
Gadoxetate (Gd-EOB-DTPA) Disodium is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system, which accumulates in normal, functioning hepatocytes. Gadoxetate Disodium aggravates liver fibrosis (LF) induced gadolinium deposition in the liver and deep cerebellar nuclei (DCN) of rats without significant acute histological alterations. Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or dysplastic nodules .
|
-
- HY-129242
-
4-Oxo-Tempo
|
SOD
|
Others
|
Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .
|
-
- HY-145746
-
|
Fluorescent Dye
|
Others
|
Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA . Sulfo-Cy5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-168929
-
|
Fluorescent Dye
Phosphatase
STAT
Apoptosis
|
Cancer
|
SHP1 activator 1 (Compound 3n) is an activator for src homology-2 domain-containing protein tyrosine phosphatase 1(SHP1) with an EC50 of 17.66 μM. SHP1 activator 1 inhibits the proliferation of ABC-DLBCL cells, induces apoptosis by inhibiting STAT3 signaling pathway. SHP1 activator 1 emitts blue and green fluorescence signalis in MDA-MB-231 cell, and can be used as a cell imaging agent .
|
-
- HY-158123
-
|
PSMA
|
Cancer
|
PSMA binder-1 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or it can be labeled with 225Ac (to obtain Actinium-225-PSMA-Trillium (BAY 3563254)), which has a radioactive killing effect; it can be used as a Macropa chelator for targeted radionuclide therapy (TRT) , has a strong inhibitory effect on metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-75706
-
|
PARP
Ligands for Target Protein for PROTAC
|
Cancer
|
N-Descyclopropanecarbaldehyde Olaparib is an analogue of Olaparib (HY-10162) containing DOTA moiety. N-Descyclopropanecarbaldehyde Olaparib is a PARP inhibitor used for synthesizing novel dual EGFR and PARP PROTAC, DP-C-4 (HY-141481) . N-Descyclopropanecarbaldehyde Olaparib can be radiolabeled with F-18 or fluorophore for positron emission tomography (PET) or optical imaging in several types of tumor .
|
-
- HY-145769
-
|
PD-1/PD-L1
|
Cancer
|
N2S2-CBMBC, an N2S2 bromo-benzyl ether derivative, acts as a ligand and use 99mTc-labelled complexes 99mTc-N2S2-CBMBC can be used as an imaging agent to be applied to the aspect of detecting PD-L1 expression, realize the real-time, comprehensive and convenient detection of the PD-L1 level of tumors, and overcome the defects of an immunohistochemical method .
|
-
- HY-116450
-
|
Dopamine Receptor
|
Neurological Disease
|
TISCH is a potent and selective iodinated ligand with high affinity and selectivity for CNS D1 dopamine receptors. TISCH showed a Kd value of 0.205 nM in rat striatal tissue, indicating its effectiveness in biological activity. TISCH is able to easily cross the blood-brain barrier and show distribution in specific areas with D1 receptor density. TISCH is considered to be useful as a pharmacological tool for characterizing D1 dopamine receptors. When labeled with I-123, TISCH has the potential to be used as an in vivo imaging agent for CNS D1 dopamine receptors .
|
-
- HY-A0168S
-
CVT-3146-d3
|
Adenosine Receptor
|
Cardiovascular Disease
Cancer
|
Regadenoson-d3 is the deuterium labeled Regadenoson. Regadenoson (CVT-3146) is a potent and selective A2A adenosine receptor agonist, with Kis of 290 and 1120 nM for rat and pig adenosine A2A receptor, respectively. Regadenoson is selective for the adenosine A2A receptor over adenosine A1 and A2B receptors, and shows 13-fold selectivity over the human adenosine A1 receptor. Regadenoson is a vasodilator stress agent has shifted the landscape of vasodilator myocardial perfusion imaging. Regadenoson increases blood-brain barrier (BBB) permeability in rodents[1][2][3].
|
-
- HY-158122
-
|
DNA-PK
|
Cancer
|
Lys(CO-C3-p-I-Ph)-O-tBu is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules. Lys(CO-C3-p-I-Ph)-O-tBu can increase the residence time of PSMA ligand in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-O-tBu also reduces salivary gland absorption, possibly extending the half-life of the active compound. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-158118
-
|
DNA-PK
|
Cancer
|
Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-170779
-
|
FAP
|
Cancer
|
DOTA-NI-FAPI-04 is a FAP inhibitor (IC50 = 7.44 nM). By integrating FAP targeting with hypoxia-sensitive groups (nitroimidazole), DOTA-NI-FAPI-04 significantly enhances tumor uptake and retention capabilities. DOTA-NI-FAPI-04 chelates metallic isotopes (such as 68Ga and 177Lu) through DOTA to produce radioactive probes ([ 68Ga]Ga/DOTA-NI-FAPI-04 and [ 177Lu]Lu/DOTA-NI-FAPI-04), which can be used for research in tumor diagnostics and therapeutic agents. DOTA-NI-FAPI-04 holds dual targeting potential in the fields of cancer imaging, tumor microenvironment analysis, and radionuclide therapy, particularly suitable for scenarios where the tumor stroma and hypoxic regions synergistically interact .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-139579
-
OTL 38
|
Fluorescent Dyes/Probes
|
Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm .
|
-
- HY-D1063
-
|
Fluorescent Dyes/Probes
|
IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging .
|
-
- HY-D1041
-
ICG NHS ester
|
Fluorescent Dyes/Probes
|
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
- HY-D1716
-
|
Fluorescent Dyes/Probes
|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
|
-
- HY-D1423
-
|
Fluorescent Dyes/Probes
|
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .
|
-
- HY-136213
-
|
Dyes
|
Endoplasmic reticulum dye 1 is a promising live cell imaging agent for the detection of exocytotic events at the plasma membrane. Endoplasmic reticulum dye 1 shows low cytotoxicity, resistance to photobleaching , which is ideal for imaging either short- or long-time courses .
|
-
- HY-D1443
-
(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
|
Fluorescent Dyes/Probes
|
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .
|
-
- HY-145385
-
|
Fluorescent Dyes/Probes
|
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca 2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .
|
-
- HY-D2378
-
-
- HY-D2335
-
|
Dyes
|
SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT). SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems .
|
-
- HY-106594B
-
Pigment blue 27
|
Fluorescent Dyes/Probes
|
Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
|
-
- HY-D1274
-
|
Fluorescent Dyes/Probes
|
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1274B
-
|
Fluorescent Dyes/Probes
|
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-136886
-
IR-820
1 Publications Verification
New Indocyanine Green
|
Fluorescent Dyes/Probes
|
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
|
-
- HY-D1274A
-
|
Fluorescent Dyes/Probes
|
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-145746
-
|
Fluorescent Dyes/Probes
|
Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA . Sulfo-Cy5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
Cat. No. |
Product Name |
Type |
-
- HY-B1684
-
SQ 26962
|
Indicators
|
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .
|
-
- HY-173384
-
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
|
Drug Delivery
|
DSPE-DOTA sodium (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt) is a chelating lipid used as a key contrast agent in magnetic resonance imaging (MRI). DSPE-DOTA sodium can be used for imaging detection of tumors, neurological and inflammatory diseases .
|
-
- HY-173383
-
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
|
Drug Delivery
|
DOPE-DOTA sodium is a chelated lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). DOPE-DOTA sodium can be used for cancer, blood-brain barrier disruption, abnormalities such as aneurysms or plaque buildup, inflammation in arthritis, and liver function and lesions study
|
-
- HY-W440919
-
|
Drug Delivery
|
DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-B1684R
-
|
Indicators
|
Mebrofenin (Standard) is the analytical standard of Mebrofenin. This product is intended for research and analytical applications. Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10023
-
|
Biochemical Assay Reagents
|
Cancer
|
Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring .
|
-
- HY-P1043A
-
|
Aminopeptidase
|
Cancer
|
NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging .
|
-
- HY-P10557
-
|
Biochemical Assay Reagents
|
Neurological Disease
|
DAG peptide is a cyclic peptide. DAG peptide selectively recognizes a subset of astrocytes that are activated in Alzheimer's disease (AD) starting at an early stage of the disease. DAG peptide can be used as a tool to enhance the delivery of therapeutics and imaging agents to sites of vascular changes and astrogliosis in diseases associated with neuroinflammation .
|
-
- HY-P10369
-
-
- HY-P10590
-
|
Fluorescent Dye
|
Cancer
|
Talogreptide mesaroxetan is a diagnostic imaging agent, with antineoplastic effect .
|
-
- HY-159526
-
-
- HY-P1043
-
|
Aminopeptidase
|
Cancer
|
NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging .
|
-
- HY-P10157
-
|
Biochemical Assay Reagents
|
Others
|
ARF(1-22) is potentially capable of intracellular penetration to deliver small molecules, proteins, imaging agents, and pharmaceutical nanocarriers .
|
-
- HY-P10012
-
GYK-DTPA
|
Biochemical Assay Reagents
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma . Pendetide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
|
-
- HY-P10911
-
|
LDLR
|
Others
|
IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM and can be used for drug- and imaging agents delivery across the blood-labyrinth barrier (BLB) .
|
-
- HY-P10792
-
|
EGFR
|
Cancer
|
HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
|
-
- HY-P10913
-
|
Bacterial
|
Infection
|
HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .
|
-
- HY-P4116
-
pHLIP
|
Peptides
|
Metabolic Disease
Cancer
|
pH-Low Insertion Peptide (pHLIP) is a short, pH-responsive peptide capable of inserting across a cell membrane to form a transmembrane helix at acidic pH. pH-Low Insertion Peptide targets the acidic tumor microenvironment for tumors at early and metastatic stages with high specificity, used as a specific ligand. pH-Low Insertion Peptide successfully modify polylysine polymers to have the pH-responsive capability. pH-Low Insertion Peptide-based targeting of cancer presents an opportunity to monitor metabolic changes, and to selectively deliver imaging and therapeutic agents to tumors .
|
-
- HY-P4116A
-
pHLIP TFA
|
Peptides
|
Metabolic Disease
Cancer
|
pH-Low Insertion Peptide TFA (pHLIP TFA) is a short, pH-responsive peptide capable of inserting across a cell membrane to form a transmembrane helix at acidic pH. pH-Low Insertion Peptide TFA targets the acidic tumor microenvironment for tumors at early and metastatic stages with high specificity, used as a specific ligand. pH-Low Insertion Peptide TFA successfully modifys polylysine polymers to have the pH-responsive capability. pH-Low Insertion Peptide TFA -based targeting of cancer presents an opportunity to monitor metabolic changes and to selectively deliver imaging and therapeutic agents to tumors .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99289
-
Antibody hLL 2
|
CD22
|
Inflammation/Immunology
Cancer
|
Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W012634
-
|
Microorganisms
Source classification
|
Bacterial
|
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent [1][2][3][4].
|
-
-
- HY-W012634R
-
|
Microorganisms
Source classification
|
Bacterial
|
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .
|
-
-
- HY-W009310R
-
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0594S
-
|
Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].
|
-
-
- HY-A0168S
-
|
Regadenoson-d3 is the deuterium labeled Regadenoson. Regadenoson (CVT-3146) is a potent and selective A2A adenosine receptor agonist, with Kis of 290 and 1120 nM for rat and pig adenosine A2A receptor, respectively. Regadenoson is selective for the adenosine A2A receptor over adenosine A1 and A2B receptors, and shows 13-fold selectivity over the human adenosine A1 receptor. Regadenoson is a vasodilator stress agent has shifted the landscape of vasodilator myocardial perfusion imaging. Regadenoson increases blood-brain barrier (BBB) permeability in rodents[1][2][3].
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-170749
-
|
|
BCN
|
DFO-BCN is a drug intermediate, that can be used for synthesis of PET/CT imaging agent DFO-CPC634 through click chemistry .
|
-
- HY-D1274
-
|
|
Azide
|
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1274B
-
|
|
Azide
|
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1274A
-
|
|
Azide
Labeling and Fluorescence Imaging
|
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-145746
-
|
|
Azide
Labeling and Fluorescence Imaging
|
Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA . Sulfo-Cy5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-W440919
-
|
|
Pegylated Lipids
Fluorescent Lipids
|
DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: