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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

IL-33 Antibody

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

5

Inhibitory Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99444
    Astegolimab
    2 Publications Verification

    MSTT 1041A; RG 6149

    		 Interleukin Related MDM-2/p53 NF-κB Cardiovascular Disease Inflammation/Immunology
    Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research .
    Astegolimab
  • HY-P990669
    Torudokimab

    		Interleukin Related Inflammation/Immunology
    Torudokimab is a humanized antibody expressed in CHO, targeting IL-33. Torudokimab has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.22 kDa. The isotype control for Torudokimab can refer to Human IgG4 kappa, Isotype Control (HY-P99003).
    Torudokimab
  • HY-P99018
    Etokimab

    Antibody ANB 020

    		 Interleukin Related Inflammation/Immunology
    Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis .
    Etokimab
  • HY-P99673
    Itepekimab

    REGN-3500; SAR-440340

    		 Interleukin Related NF-κB Inflammation/Immunology
    Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD) .
    Itepekimab
  • HY-P99729
    Melrilimab

    GSK 3772847; CNTO-7160

    		 Interleukin Related Inflammation/Immunology
    Melrilimab (GSK 3772847) is an IgG2-kappa anti-IL1RL1/ST2/IL33R/DER4/FIT-1 monoclonal antibody. Melrilimab can be used for the research of asthma .
    Melrilimab

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