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Results for "

Human immunoglobulin E

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Inhibitory Antibodies

2

Recombinant Proteins

2

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P9950
    Omalizumab
    1 Publications Verification

    Olizumab; rhuMab-E25

    		 Interleukin Related Inflammation/Immunology Cancer
    Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a KD of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a KD of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research .
    Omalizumab
  • HY-NP201
    Human immunoglobulin E

    Human IgE

    		 Biochemical Assay Reagents Inflammation/Immunology
    Human immunoglobulin E (Human IgE) is a key mediator in allergic diseases. Human immunoglobulin E is made up of heavy (H) and light (L) chains, of which the variable (V) domains of the H chains are believed to contribute much to their antigenbinding properties .
    Human immunoglobulin E
  • HY-169051
    SIRT-IN-5

    		Sirtuin Cancer
    SIRT-IN-5 is a SIRT3 inhibitor, with an IC50 value of 2.88 μM. SIRT-IN-5 can promote the differentiation of multiple myeloma cells, along with an increase in the expression of the differentiation antigen CD49e and human immunoglobulin light chains λ and κ .
    SIRT-IN-5
  • HY-165484
    AVP-13358

    		Interleukin Related Inflammation/Immunology
    AVP-13358 is an orally active IgE inhibitor that effectively suppresses immunoglobulin E (IgE)-mediated immune responses, with IC50 values of 8 and 3 nM for IgE inhibition in vivo and in vitro in BALB/c mice, respectively. AVP-13358 acts directly on T cells, inhibiting the production and release of IL-4, IL-5, and IL-13. It also targets other markers critical for the development of allergic responses, including the B cell IgE receptor (CD23) in human monocytes and the CD23 and IL-4 receptors in mouse B cells. AVP-13358 can be used in research related to anti-allergic responses .
    AVP-13358

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