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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

HuCCA-1 cells

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119631
    Nornidulin

    		Bacterial Infection
    Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC=2 μg/mL).2 Nornidulin has cytotoxic activity in MOLT-3 cells (IC50=35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s=>116.4 μM).
    Nornidulin
  • HY-N16402
    Aspergillusidone D

    		Cytochrome P450 Endogenous Metabolite Cancer
    Aspergillusidone D (Compound 1), a brominated depsidone, is a Aromatase inhibitor with an IC50 of 0.8  μM. Aspergillusidone D can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone D has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone D can be used for cancers like breast cancer research .
    Aspergillusidone D
  • HY-N16403
    Aspergillusidone F

    		Cytochrome P450 Endogenous Metabolite Drug Isomer Cancer
    Aspergillusidone F (Compound 3), a brominated depsidone, is a regioisomer of Aspergillusidone D (HY-N16402). Aspergillusidone F is a Aromatase inhibitor with an IC50 of 0.5  μM. Aspergillusidone F can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone F has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone F can be used for cancers like breast cancer research .
    Aspergillusidone F

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