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HDAC-IN-94

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-179019
    HDAC-IN-94

    		HDAC Microtubule/Tubulin Apoptosis Caspase Neurological Disease Cancer
    HDAC-IN-94 is a potent, selective HDAC6 inhibitor (IC50 = 4.5 nM). HDAC-IN-94 shows >1000-fold selectivity over HDAC8 and shows minimal activity against other isoforms (HDAC1-3, 10). HDAC-IN-94 induces α-tubulin hyperacetylation, apoptosis, and G2/M cell cycle arrest, exhibiting potent anti-tumor efficacy with low cytotoxicity. HDAC-IN-94 can be used for neuroblastoma and glioblastoma research .
    HDAC-IN-94

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