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Results for "

Glycyrrhizin

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

6

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0184
    Glycyrrhizic acid
    40+ Cited Publications

    Glycyrrhizin

    		 Virus Protease Metabolic Disease Cancer
    Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid
  • HY-N11111
    Glycyrrhizin-6'-methylester

    		Others Others
    Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .
    Glycyrrhizin-6'-methylester
  • HY-N6851
    Glycyrrhetic acid 3-O-β-D-glucuronide

    Glycyrrhetic acid 3-O-mono-β-D-glucuronide; 3-monoglucuronyl-glycyrrhetinic acid

    		 Others Inflammation/Immunology
    Glycyrrhetic acid 3-O-β-D-glucuronide, isolated from glycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity . Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β-glucuronidases (β-GUS) are key GAMG-producing enzymes, displaying a high potential to convert GL directly into GAMG .Glycyrrhetic acid 3-O-β-D-glucuronide is valuable as a sweetener.
    Glycyrrhetic acid 3-O-β-D-glucuronide
  • HY-N11976
    Glycyrrhizin-6′′-methylester

    		Others Others
    Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .
    Glycyrrhizin-6′′-methylester
  • HY-N11975
    Glycyrrhizin-6′,6′′-dimethylester

    		Others Others
    Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .
    Glycyrrhizin-6′,6′′-dimethylester
  • HY-N0184R
    Glycyrrhizic acid (Standard)

    Glycyrrhizin (Standard)

    		 Reference Standards Virus Protease Metabolic Disease Cancer
    Glycyrrhizic acid (Standard) is the analytical standard of Glycyrrhizic acid. This product is intended for research and analytical applications. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid (Standard)
  • HY-155759
    HMGB1-IN-2

    		NF-κB Interleukin Related Caspase Apoptosis Inflammation/Immunology Cancer
    HMGB1-IN-2 (compound 15) is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC50 value of 20.2 μM in RAW264.7 cells. HMGB1-IN-2 (30 μM) decreases the level of IL-1 β, TNF-α, caspase-1 p20, inhibits the phosphorylation of NF-κB p65, exhibits anti-apoptotic activity. HMGB1-IN-2 (15 mg/kg; ip) relives kidney injury in septic acute kidney injury mouse. HMGB1-IN-2 inhibits Huh7 cells and A549 cells with IC50s of 77.0 μM, and 82.0 μM, respectively .
    HMGB1-IN-2

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