2. Search Result
Search Result
Results for "

Glycine (Standard)

" in MedChemExpress (MCE) Product Catalog:

42

Inhibitors & Agonists

2

Biochemical Assay Reagents

4

Peptides

31

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0966R
    Glycine (Standard)

    		Endogenous Metabolite iGluR VEGFR Neurological Disease
    Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis .
    Glycine (Standard)
  • HY-N1424R
    Glycoursodeoxycholic acid (Standard)

    		Endogenous Metabolite Neurological Disease
    Glycoursodeoxycholic acid (Standard) is the analytical standard of Glycoursodeoxycholic acid. This product is intended for research and analytical applications. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.
    Glycoursodeoxycholic acid (Standard)
  • HY-77519R
    N-(4-Cyanophenyl)glycine (Standard)

    		Amino Acid Derivatives Others
    N-(4-Cyanophenyl)glycine (Standard) is the analytical standard of N-(4-Cyanophenyl)glycine. This product is intended for research and analytical applications. N-(4-Cyanophenyl)glycine is a Glycine (HY-Y0966) derivative .
    N-(4-Cyanophenyl)glycine (Standard)
  • HY-N7403R
    N-(3-Phenylpropionyl)glycine (Standard)

    		Amino Acid Derivatives Others
    N-(3-Phenylpropionyl)glycine (Standard) is the analytical standard of N-(3-Phenylpropionyl)glycine. This product is intended for research and analytical applications. N-(3-Phenylpropionyl)glycine is a Glycine (HY-Y0966) derivative .
    N-(3-Phenylpropionyl)glycine (Standard)
  • HY-W074890R
    Palmitoylglycine (Standard)

    N-palmitoyl Glycine (Standard)

    		 Calcium Channel NO Synthase Neurological Disease Inflammation/Immunology
    Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].
    Palmitoylglycine (Standard)
  • HY-113204R
    N-Oleoyl glycine (Standard)

    		Endogenous Metabolite Cannabinoid Receptor Akt Metabolic Disease
    Diludine (Standard) is the analytical standard of Diludine. This product is intended for research and analytical applications. Diludine has antioxidant properties, targeting oxidative stress-related pathways. By improving antioxidative status and reducing β-hydroxybutyrate levels, Diludine alleviates oxidative stress during the parturition period in dairy cows. It is primarily used during the transition period in dairy cows to increase milk yield and milk fat content, as well as to improve health during parturition .
    N-Oleoyl glycine (Standard)
  • HY-10809R
    Bitopertin (Standard)

    		GlyT Neurological Disease
    Bitopertin (Standard) is the analytical standard of Bitopertin. This product is intended for research and analytical applications. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.
    Bitopertin (Standard)
  • HY-113085R
    3-Hydroxyhippuric acid (Standard)

    		Endogenous Metabolite Others
    3-Hydroxyhippuric acid (Standard) is the analytical standard of 3-Hydroxyhippuric acid. This product is intended for research and analytical applications. 3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.
    3-Hydroxyhippuric acid (Standard)
  • HY-113210R
    Hydroxyphenylacetylglycine (Standard)

    		Endogenous Metabolite Metabolic Disease
    Hydroxyphenylacetylglycine (Standard) is the analytical standard of Hydroxyphenylacetylglycine. This product is intended for research and analytical applications. Hydroxyphenylacetylglycine is an acyl glycine, and an endogenous human metabolite.
    Hydroxyphenylacetylglycine (Standard)
  • HY-113353R
    Nicotinuric acid (Standard)

    		Endogenous Metabolite Others
    Nicotinuric acid (Standard) is the analytical standard of Nicotinuric acid. This product is intended for research and analytical applications. Nicotinuric acid is an acyl glycine. Nicotinuric acid is a metabolite of nicotinic acid.
    Nicotinuric acid (Standard)
  • HY-113367R
    Suberylglycine (Standard)

    		Endogenous Metabolite Metabolic Disease
    Suberylglycine (Standard) is the analytical standard of Suberylglycine. This product is intended for research and analytical applications. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.
    Suberylglycine (Standard)
  • HY-W015464R
    N-Isovaleroylglycine (Standard)

    		Endogenous Metabolite Metabolic Disease
    N-Isovaleroylglycine (Standard) is the analytical standard of N-Isovaleroylglycine. This product is intended for research and analytical applications. N-Isovaleroylglycine is an acyl glycine and could be used as a biomarker for the predispositon for weight gain and obesity.
    N-Isovaleroylglycine (Standard)
  • HY-101037R
    Sarcosine (Standard)

    N-MethylGlycine (Standard); Sarcosin (Standard)

    		 Reference Standards Endogenous Metabolite GlyT Cancer
    Sarcosine (Standard) is the analytical standard of Sarcosine. This product is intended for research and analytical applications. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia .
    Sarcosine (Standard)
  • HY-41700R
    D-Alanine (Standard)

    		Endogenous Metabolite Neurological Disease
    D-Alanine (Standard) is the analytical standard of D-Alanine. This product is intended for research and analytical applications. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR .
    D-Alanine (Standard)
  • HY-118700AR
    2-Iminobiotin (hydrobromide) (Standard)

    		NO Synthase Neurological Disease
    H-Gly-Gly-Gly-OH (Standard) is the analytical standard of H-Gly-Gly-Gly-OH. This product is intended for research and analytical applications. H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.
    2-Iminobiotin (hydrobromide) (Standard)
  • HY-W015236R
    H-Gly-Gly-Gly-OH (Standard)

    		Biochemical Assay Reagents Others
    H-Gly-Gly-Gly-OH (Standard) is the analytical standard of H-Gly-Gly-Gly-OH. This product is intended for research and analytical applications. H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.
    H-Gly-Gly-Gly-OH (Standard)
  • HY-100803R
    Hypotaurine (Standard)

    2-Aminoethanesulfinic acid (Standard)

    		 Reference Standards Endogenous Metabolite Neurological Disease
    Hypotaurine (Standard) is the analytical standard of Hypotaurine. This product is intended for research and analytical applications. Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. Antioxidant[1].
    Hypotaurine (Standard)
  • HY-101397R
    Allopurinol riboside (Standard)

    		Reference Standards Parasite Drug Metabolite Endogenous Metabolite Infection
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .
    Allopurinol riboside (Standard)
  • HY-N0324R
    Cholic acid (Standard)
    10+ Cited Publications

    		 Endogenous Metabolite Metabolic Disease
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .
    Cholic acid (Standard)
  • HY-N0658AR
    DL-Threonine (Standard)

    		Endogenous Metabolite Inflammation/Immunology
    DL-Threonine (Standard) is the analytical standard of DL-Threonine. This product is intended for research and analytical applications. DL-Threonine, an essential amino acid, is a precursor of Glycine (HY-Y0966). DL-Threonine has the potential for the study of hypostatic leg ulceration.
    DL-Threonine (Standard)
  • HY-N0324AR
    Cholic acid sodium (Standard)

    Sodium cholate (Standard)

    		 Endogenous Metabolite Metabolic Disease
    Cholic acid (sodium) (Standard) is the analytical standard of Cholic acid (sodium). This product is intended for research and analytical applications. Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active[1][2].
    Cholic acid sodium (Standard)
  • HY-D0187R
    L-Glutathione reduced (Standard)

    		Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
    L-Glutathione reduced (Standard)
  • HY-77641R
    Cinnamoylglycine (Standard)

    		Endogenous Metabolite Metabolic Disease
    Cinnamoylglycine (Standard) is the analytical standard of Cinnamoylglycine. This product is intended for research and analytical applications. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .
    Cinnamoylglycine (Standard)
  • HY-B0863R
    Glyphosate (Standard)

    		Apoptosis Autophagy Necroptosis Cancer
    Glyphosate (Standard) is the analytical standard of Glyphosate. This product is intended for research and analytical applications. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .
    Glyphosate (Standard)
  • HY-Y0511R
    N,N-Dimethylglycine (Standard)

    DimethylGlycine (Standard); DMG (Standard); N-Methylsarcosine (Standard)

    		 Endogenous Metabolite iGluR Amino Acid Derivatives Neurological Disease Metabolic Disease
    N,N-Dimethylglycine (Dimethylglycine) (Standard) is the analytical standard of N,N-Dimethylglycine (HY-Y0511). This product is intended for research and analytical applications. N,N-Dimethylglycine (Dimethylglycine), a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine has antidepressant-like and surfactant effects.
    N,N-Dimethylglycine (Standard)
  • HY-116374R
    Glycolithocholic acid (Standard)

    LithocholylGlycine (Standard)

    		 Endogenous Metabolite Inflammation/Immunology
    Glycolithocholic acid (Standard) is the analytical standard of Glycolithocholic acid. This product is intended for research and analytical applications. Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .
    Glycolithocholic acid (Standard)
  • HY-130466R
    Stearoyl-L-carnitine chloride (Standard)

    		Endogenous Metabolite GlyT Metabolic Disease
    Stearoyl-L-carnitine (chloride) (Standard) is the analytical standard of Stearoyl-L-carnitine (chloride). This product is intended for research and analytical applications. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
    Stearoyl-L-carnitine chloride (Standard)
  • HY-N0301R
    Thiocolchicoside (Standard)

    		GABA Receptor Neurological Disease Inflammation/Immunology
    Thiocolchicoside (Standard) is the analytical standard of Thiocolchicoside. This product is intended for research and analytical applications. Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .
    Thiocolchicoside (Standard)
  • HY-113329R
    Guanidinoethyl sulfonate (Standard)

    		Endogenous Metabolite Metabolic Disease
    Guanidinoethyl sulfonate (Standard) is the analytical standard of Guanidinoethyl sulfonate. This product is intended for research and analytical applications. Guanidinoethyl sulfonate is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury .
    Guanidinoethyl sulfonate (Standard)
  • HY-107782R
    Picrotin (Standard)

    		GABA Receptor Reference Standards Neurological Disease
    Picrotin (Standard) is the analytical standard of Picrotin. This product is intended for research and analytical applications. Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission .
    Picrotin (Standard)
  • HY-122141R
    Glycohyocholic acid (Standard)

    GHCA (Standard)

    		 Reference Standards Endogenous Metabolite Infection Metabolic Disease
    Glycohyocholic acid (Standard) is the analytical standard of Glycohyocholic acid (HY-122141). This product is intended for use in research and analytical applications. Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966). Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus .
    Glycohyocholic acid (Standard)
  • HY-100834R
    5,7-Dichlorokynurenic acid (Standard)

    5,7-DCKA (Standard)

    		 Reference Standards iGluR Neurological Disease
    5,7-Dichlorokynurenic acid (Standard) is the analytical standard of 5,7-Dichlorokynurenic acid. This product is intended for research and analytical applications. 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduced NMDA-induced neuron injury in rat cortical cell cultures .
    5,7-Dichlorokynurenic acid (Standard)
  • HY-W015912R
    2-Acetylfuran (Standard)

    		Others Others
    2-Acetylfuran (Standard) is the analytical standard of 2-Acetylfuran. This product is intended for research and analytical applications. 2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime .
    2-Acetylfuran (Standard)
  • HY-100811AR
    7-Chlorokynurenic acid sodium salt (Standard)

    7-CKA sodium salt (Standard)

    		 Reference Standards iGluR Neurological Disease
    7-Chlorokynurenic acid (sodium salt) (Standard) is the analytical standard of 7-Chlorokynurenic acid (sodium salt). This product is intended for research and analytical applications. 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery .
    7-Chlorokynurenic acid sodium salt (Standard)
  • HY-100811R
    7-Chlorokynurenic acid (Standard)

    7-CKA (Standard)

    		 Reference Standards iGluR Neurological Disease
    7-Chlorokynurenic acid (Standard) is the analytical standard of 7-Chlorokynurenic acid. This product is intended for research and analytical applications. 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery .
    7-Chlorokynurenic acid (Standard)
  • HY-N2334R
    Glycochenodeoxycholic acid (Standard)

    ChenodeoxycholylGlycine (Standard)

    		 Endogenous Metabolite Apoptosis STAT BCL6 Interleukin Related Caspase Metabolic Disease Cancer
    Glycochenodeoxycholic acid (Standard) is the analytical standard of Glycochenodeoxycholic acid. This product is intended for research and analytical applications. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4].
    Glycochenodeoxycholic acid (Standard)
  • HY-N0215R
    L-Phenylalanine (Standard)

    		Calcium Channel iGluR Endogenous Metabolite Metabolic Disease
    L-Phenylalanine (Standard) is the analytical standard of L-Phenylalanine. This product is intended for research and analytical applications. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .
    L-Phenylalanine (Standard)
  • HY-138813R
    N-Desethyl Sunitinib (hydrochloride) (Standard)

    		Drug Metabolite Cancer
    Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) .
    N-Desethyl Sunitinib (hydrochloride) (Standard)
  • HY-B1119R
    Triclosan (Standard)

    		Reference Standards Bacterial Fungal Antibiotic Apoptosis Infection Cancer
    Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
    Triclosan (Standard)
  • HY-N2334AR
    Glycochenodeoxycholic acid sodium salt (Standard)

    		Endogenous Metabolite Apoptosis STAT BCL6 Interleukin Related Caspase Metabolic Disease Cancer
    Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) .
    Glycochenodeoxycholic acid sodium salt (Standard)
  • HY-16569R
    Colchicine (Standard)

    		Reference Standards Microtubule/Tubulin NOD-like Receptor (NLR) Autophagy Apoptosis Cancer
    Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
    Colchicine (Standard)
  • HY-D0889R
    Glycylglycine (Standard)

    		Endogenous Metabolite Metabolic Disease
    Glycylglycine (Standard) is the analytical standard of Glycylglycine (HY-D0889). This product is intended for research and analytical applications. Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
    Glycylglycine (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: