2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Guanidinoethyl sulfonate (Standard)

Guanidinoethyl sulfonate (Standard) 

Cat. No.: HY-113329R Purity: ≥98%
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Guanidinoethyl sulfonate (Standard) is the analytical standard of Guanidinoethyl sulfonate. This product is intended for research and analytical applications. Guanidinoethyl sulfonate is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury.

For research use only. We do not sell to patients.

Guanidinoethyl sulfonate (Standard) Chemical Structure

Guanidinoethyl sulfonate (Standard) Chemical Structure

CAS No. : 543-18-0

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Guanidinoethyl sulfonate (Standard) Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guanidinoethyl sulfonate (Standard)543-18-0Endogenous Metabolitetaurine transport antagonistInhibitorinhibitorinhibit

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