Glucose 6-phosphate isomerase

By Targets:	Glucose-6-Phosphate Isomerase (GPI) (1) Akt (1) Apoptosis (1) Biochemical Assay Reagents (1) Casein Kinase (1) Endogenous Metabolite (6) Flavivirus (1) mTOR (1) PI3K (1) Reference Standards (1) Virus Protease (1)
By Research Areas:	Cancer (2) Infection (1) Metabolic Disease (6) Neurological Disease (2)

Targets Recommended: Glucose-6-Phosphate Isomerase (GPI) Phosphomannose Isomerase (PMI) Sodium Phosphate Cotransporter Carbamoyl Phosphate Synthetase (CPS) GLUT SGLT PIKfyve PIN1 Pyruvate Oxidase PI4P5K

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011184

6-Phosphogluconic acid trisodium	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid trisodium is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_i*s of 48 μM for glucose* 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-P2918

Phosphoglucose Isomerase, Rabbit muscle GPI; PhosphoGlucose isomerase	Endogenous Metabolite	Metabolic Disease Cancer
Phosphoglucose Isomerase, Rabbit muscle (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .

HY-113514

6-Phosphogluconic acid	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_i*s of 48 μM for glucose* 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

HY-N6841

Rhodiolin	Glucose-6-Phosphate Isomerase (GPI) Casein Kinase Virus Protease Flavivirus PI3K Akt mTOR Apoptosis	Infection Cancer
Rhodiolin, a flavonoid, is an orally active glucose 6-phosphate isomerase (GPI) inhibitor. Rhodiolin inhibits papillary thyroid cancer (PTC) by targeting glycolysis enzyme glucose 6-phosphate isomerase GPI and suppressing PI3K/AKT/mTOR phosphorylation and induce apoptosis. Rhodiolin as a NS2B-NS3 protease inhibitor can disrupt dengue viral replication. Rhodiolin is also a potential candidate for developing anticancer strategies inhibiting CK1ε kinase. Rhodiolin can be used for the study of anti-tumor and anti-viral .

HY-167805

D-Glucose 6-phosphate potassium	Biochemical Assay Reagents
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-W725496

D-Fructose 6-phosphate dipotassium	Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate dipotassium is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose 6-phosphate dipotassium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate dipotassium can be used to study Lewy body dementia .

HY-W011184R

6-Phosphogluconic acid trisodium (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_i*s of 48 μM for glucose* 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.

HY-113407

D-Fructose-6-phosphate	Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate can be used to study Lewy body dementia .

Cat. No.	Product Name	Type

HY-167805

D-Glucose 6-phosphate potassium	Enzyme Substrates
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-W725496

D-Fructose 6-phosphate dipotassium	Carbohydrates
D-Fructose 6-phosphate dipotassium is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose 6-phosphate dipotassium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate dipotassium can be used to study Lewy body dementia .

D-Fructose 6-phosphate dipotassium

Carbohydrates

D-Fructose 6-phosphate dipotassium is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose 6-phosphate dipotassium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate dipotassium can be used to study Lewy body dementia .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011184

6-Phosphogluconic acid trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
6-Phosphogluconic acid trisodium is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_i*s of 48 μM for glucose* 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-113514

6-Phosphogluconic acid	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
6-Phosphogluconic acid is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_i*s of 48 μM for glucose* 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

HY-N6841

Rhodiolin	Flavonols Structural Classification Flavonoids Classification of Application Fields Rhodiola rosea Linn. Crassulaceae Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Glucose-6-Phosphate Isomerase (GPI) Casein Kinase Virus Protease Flavivirus PI3K Akt mTOR Apoptosis
Rhodiolin, a flavonoid, is an orally active glucose 6-phosphate isomerase (GPI) inhibitor. Rhodiolin inhibits papillary thyroid cancer (PTC) by targeting glycolysis enzyme glucose 6-phosphate isomerase GPI and suppressing PI3K/AKT/mTOR phosphorylation and induce apoptosis. Rhodiolin as a NS2B-NS3 protease inhibitor can disrupt dengue viral replication. Rhodiolin is also a potential candidate for developing anticancer strategies inhibiting CK1ε kinase. Rhodiolin can be used for the study of anti-tumor and anti-viral .

HY-W011184R

6-Phosphogluconic acid trisodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive *phosphoglucose isomerase* (PGI) inhibitor with K_i*s of 48 μM for glucose* 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.

HY-113407

D-Fructose-6-phosphate	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
D-Fructose 6-phosphate is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate can be used to study Lewy body dementia .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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