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GPR84 agonist-2

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173556

    GPR84 Inflammation/Immunology
    GPR84 agonist-2 (Compound 8e) is a highly selective GPR84 agonist with an EC50 value of 7.24 nM. GPR84 agonist-2 activates the Gαq signaling pathway, promoting inositol trisphosphate (IP3) production and calcium release and enhancing neutrophil chemotaxis and pro-inflammatory cytokine release. GPR84 agonist-2 is promising for research of inflammatory diseases, such as ulcerative colitis and acute lung injury .
    GPR84 agonist-2

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