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Results for "

Fungal defense

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y1058
    Benzohydroxamic acid

    BHA

    		 Fungal Infection
    Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with significant antifungal activity. The Ki values of BHA against the CDAs of Verticillium dahliae and Puccinia striiformis f. sp. tritici are 8.31 μM and 9.83 μM, respectively. Benzohydroxamic acid can restore the defense responses of infected host plants, upregulate the expression of defense-related genes, and reduce the growth and reproduction of fungi in plants. Benzohydroxamic acid can be used in the research of the field of controlling agricultural fungal diseases, such as various plant fungal diseases caused by Verticillium dahliae, Puccinia striiformis and other fungi, like cotton wilt and wheat stripe rust .
    Benzohydroxamic acid
  • HY-N12106
    Neosartoricin

    Fumicycline

    		 Endogenous Metabolite Fungal Infection
    Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence .
    Neosartoricin
  • HY-P11093
    Papiliocin

    		Antibiotic Bacterial Fungal Apoptosis Reactive Oxygen Species (ROS) TNF Receptor NO Synthase Interleukin Related NF-κB Toll-like Receptor (TLR) Infection Inflammation/Immunology
    Papiliocin is a potent peptide antibiotic with both anti-inflammatory and antibacterial activities. Papiliocin is primarily active against Gram-negative bacteria. Papiliocin exhibits strong anti-inflammatory activity against cell, exerting its anti-inflammatory activity by inhibiting the production of NO and the secretion of TNF-α and MIP-2. Papiliocin participates in the innate defense response mechanism by inhibiting the Toll-like receptor pathway and NF-κB. Papiliocin induces apoptosis in fungal cells and increases the total level of intracellular ROS. Papiliocin acts as an effective antiseptic peptide in sepsis models. Papiliocin is useful in anti-inflammatory and antibacterial research .
    Papiliocin

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