2. Search Result
Search Result
Results for "

Fulvestrant

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13636
    Fulvestrant
    100+ Cited Publications

    ICI 182780; ZD 9238; ZM 182780

    		 Estrogen Receptor/ERR Autophagy Apoptosis Cancer
    Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
    Fulvestrant
  • HY-148225
    Fulvestrant 3-β-D-Glucuronide

    		Drug Metabolite Cancer
    Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer .
    Fulvestrant 3-β-D-Glucuronide
  • HY-137144
    Fulvestrant-3-boronic acid

    ZB716

    		 Estrogen Receptor/ERR Cancer
    Fulvestrant-3-boronic acid is an orally active ERα inhibitor, which binds to ERα competitively (IC50 = 4.1 nM) and effectively degrades ERα in breast cancer cells .
    Fulvestrant-3-boronic acid
  • HY-13636R
    Fulvestrant (Standard)
    100+ Cited Publications

    ICI 182780(Standard); ZD 9238(Standard); ZM 182780 (Standard)

    		 Reference Standards Estrogen Receptor/ERR Autophagy Apoptosis Cancer
    Fulvestrant (Standard) is the analytical standard of Fulvestrant. This product is intended for research and analytical applications. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
    Fulvestrant (Standard)
  • HY-13636S
    Fulvestrant-d3

    ICI 182780-d3; ZD 9238-d3; ZM 182780-d3

    		 Isotope-Labeled Compounds Estrogen Receptor/ERR Autophagy Apoptosis Cancer
    Fulvestrant-d3 is the deuterium labeled Fulvestrant. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
    Fulvestrant-d3
  • HY-79315
    6-Dehydronandrolone acetate

    		Estrogen Receptor/ERR Others
    6-Dehydronandrolone acetate is a starting material for synthesis of Fulvestrant. Fulvestrant is an estrogen receptor antagonist that can be used for the research of breast cancer .
    6-Dehydronandrolone acetate
  • HY-146485S
    Fulvestrant-9-sulfone-d3

    		Isotope-Labeled Compounds Others
    Fulvestrant-9-sulfone-d3 is the deuterium labeled Fulvestrant-9-sulfone .
    Fulvestrant-9-sulfone-d3
  • HY-13636A
    Fulvestrant (S enantiomer)

    ICI 182780 (S enantiomer); ZD 9238 (S enantiomer); ZM 182780 (S enantiomer)

    		 Estrogen Receptor/ERR Cancer
    Fulvestrant S enantiomer (ICI 182780 S enantiomer) is the S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
    Fulvestrant (S enantiomer)
  • HY-13636B
    Fulvestrant (R enantiomer)

    ICI 182780 (R enantiomer); ZD 9238 (R enantiomer); ZM 182780 (R enantiomer)

    		 Estrogen Receptor/ERR Cancer
    Fulvestrant R enantiomer (ICI 182780 R enantiomer) is the R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
    Fulvestrant (R enantiomer)
  • HY-13636S1
    Fulvestrant-d5

    ICI 182780-d5; ZD 9238-d5; ZM 182780-d5

    		 Isotope-Labeled Compounds Others
    Fulvestrant-d5 is a isotope of Fulvestrant .
    Fulvestrant-d5
  • HY-137449
    Rintodestrant

    G1T48

    		 Estrogen Receptor/ERR CDK Cancer
    Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor .
    Rintodestrant
  • HY-155406
    Estrogen receptor modulator 10

    		Estrogen Receptor/ERR Caspase Bcl-2 Family Cancer
    Estrogen receptor modulator 10 (compound G-5b) is an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). Estrogen receptor modulator 10 is developed based on the Fulvestrant (HY-13636) molecule and can rapidly degrade ER receptors through the proteasome pathway. Estrogen receptor modulator 10 can induce cell apoptosis and block cells in the G1/G0 phase and can be used in cancer research .
    Estrogen receptor modulator 10
  • HY-176225
    BY13

    		PROTACs Src Estrogen Receptor/ERR Apoptosis
    BY13 is a SRC-3 PROTAC degrader with a DC50 of 0.031 μM. BY13 selectively blocks the ER signaling pathway over that of androgen receptor (AR)) through down-regulating ERα level. BY13 potently overcomes endocrine resistance in breast cancer by inducing cell cycle arrest in G1 phase and apoptosis, with superior effect over Fulvestrant (HY-13636). BY13 significantly inhibits the growth of drug-resistant breast tumors without obvious toxicity in LCC2 xenograft mice model . Pink: SRC-3 ligand (SI-2) (HY-101447); Blue: CRBN ligase ligand (HY-41547); Black: linker (HY-176226)
    BY13

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: