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Results for "

Filovirus

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-U00160
    SP187
    3 Publications Verification

    MON-​DNJ; UV4

    		 Flavivirus Dengue Virus Infection
    SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
    SP187
  • HY-P99722
    Maftivimab

    REGN3470-3471-3479

    		 Filovirus Infection
    Maftivimab (REGN3470-3471-3479), the inhibitor of Filovirus, is an Food and agent Administration (FDA)-approved agent. Maftivimab, also named as Atoltivimab, Odesivimab (Inmazeb), can be used for research of Zaire ebolavirus infection .
    Maftivimab
  • HY-107613A
    R 59-022 hydrochloride
    1 Publications Verification

    DKGI-I hydrochloride; Diacylglycerol kinase inhibitor I hydrochloride

    		 PKC 5-HT Receptor Infection Inflammation/Immunology Cancer
    R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 µM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils .
    R 59-022 hydrochloride
  • HY-107613
    R 59-022
    1 Publications Verification

    DKGI-I; Diacylglycerol kinase inhibitor I

    		 PKC 5-HT Receptor Inflammation/Immunology
    R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils .
    R 59-022
  • HY-W143403A
    (-)-Isopinocampheol

    l-Isopinocampheol

    		 Filovirus Others
    (-)-Isopinocampheol (l-Isopinocampheol) is a compound with anti-filovirus activity. Its derivatives inhibit infection by Ebola virus and Marburg virus, possibly through binding to surface glycoproteins. It also has lysosomal affinity.
    (-)-Isopinocampheol
  • HY-170547
    DNA polymerase-IN-6

    		DNA/RNA Synthesis HSV Filovirus Infection
    DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, and inhibits HCMV, HSV-1, HSV-2 and EBV with EC50s of 0.33, 1.9, 0.76 and 0.066 µM, respectively .
    DNA polymerase-IN-6
  • HY-170493
    Antiviral agent 66

    		Filovirus Infection
    Antiviral agent 66 (Compound 60) is the inhibitor for Filovirus, that inhibits pseudotyped virus of Ebola, Marburg, Zaire, Sudan, Bundibugyo, Reston and Tai Forest with EC50s of 0.16, 2.24, 0.16, 0.89, 0.21, 0.21 and 0.11 μM, respectively .
    Antiviral agent 66
  • HY-173508
    EBOV entry-IN-1

    		Filovirus Infection
    EBOV entry-IN-1 (compound Hu7) is an EBOV entry inhibitor with an IC50 of 1.50 μM .
    EBOV entry-IN-1
  • HY-105070A
    Eritoran tetrasodium

    E5564

    		 EBV Toll-like Receptor (TLR) Infection Inflammation/Immunology
    Eritoran tetrasodium (E5564) is a Toll-like receptor 4 (TLR4) antagonist. Eritoran tetrasodium protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran tetrasodium decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran tetrasodium inhibits pathogenesis of filovirus infection. Eritoran tetrasodium has anti-inflammatory activity .
    Eritoran tetrasodium

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