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FKBP12F36V

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114421
    FKBP12 PROTAC dTAG-13
    3 Publications Verification

    dTAG-13

    		 PROTACs FKBP Cancer
    FKBP12 PROTAC dTAG-13 (dTAG-13), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12 F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 effectively engages FKBP12 F36V and CRBN, thereby selectively degrading FKBP12 F36V .
    FKBP12 PROTAC dTAG-13
  • HY-161157
    dTAG-13-NEG

    		PROTACs Cancer
    dTAG-13-NEG is a negative control of dTAG-13. dTAG-13 (HY-114421), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12 F36V with expression of FKBP12F36V in-frame with a protein of interest .
    dTAG-13-NEG
  • HY-147098
    dTAG-47

    		PROTACs FKBP Cancer
    dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12 F36V). FKBP12 F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC) .
    dTAG-47
  • HY-129363
    AP1867-3-(aminoethoxy)

    		Ligands for Target Protein for PROTAC FKBP Cancer
    AP1867-3-(aminoethoxy), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(aminoethoxy) can be used in the synthesis of PROTAC FKBP12 F36V degrader .
    AP1867-3-(aminoethoxy)
  • HY-135250B
    Thalidomide-4-O-C6-NH2 hydrochloride

    		E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12 F36V and BET .
    Thalidomide-4-O-C6-NH2 hydrochloride
  • HY-135250A
    Thalidomide-4-O-C6-NH2 TFA

    		E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-4-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13 (HY-114421), a degrader of FKBP12 F36V and BET .
    Thalidomide-4-O-C6-NH2 TFA
  • HY-123941
    FKBP12 PROTAC dTAG-7
    2 Publications Verification

    dTAG-7

    		 PROTACs FKBP Epigenetic Reader Domain Others
    FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional PROTAC degrader. FKBP12 PROTAC dTAG-7 targets FKBP12 F36V and BET BRD4. FKBP12 PROTAC dTAG-7 enables rapid and selective degradation of target proteins, and is suitable for cellular and in vivo studies to analyze protein functions and validate targets . (Pink: target protein ligand (HY-114420); Black: linker (HY-128844); Blue: CRBN Ligand (HY-103597); CRBN Ligand+linker: (HY-W722323))
    FKBP12 PROTAC dTAG-7
  • HY-114434
    AP1867
    3 Publications Verification

    		 FKBP Cancer
    AP1867 is a synthetic FKBP12 F36V-directed ligand .
    AP1867
  • HY-145514
    dTAGV-1 TFA
    1 Publications Verification

    		 PROTACs FKBP Cancer
    dTAGV-1 TFA is a potent and selective degrader of FKBP12 F36V-tagged proteins PROTAC degrader. dTAGV-1 TFA can induce degradation of FKBP12 F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A))
    dTAGV-1 TFA

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