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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

Enzyme replacement therapy

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

3

Inhibitory Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153592
    Therapeutic agent-1

    		Glycosidase Others
    Therapeutic agent-1 is a heteroaryl compound that can be used in Gaucher disease glucocerebrosidase activity enzyme replacement therapy .
    Therapeutic agent-1
  • HY-108786
    Asfotase alfa

    ENB-0040

    		 Phosphatase Metabolic Disease
    Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 / knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) .
    Asfotase alfa
  • HY-P991677
    Efmirenpase alfa

    		Phosphodiesterase (PDE) Cardiovascular Disease Endocrinology
    Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research .
    Efmirenpase alfa
  • HY-P991210
    Efzimfotase alfa

    ALXN-1850

    		 Phosphatase Cardiovascular Disease
    Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .
    Efzimfotase alfa

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