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EGFR WT/T790M-IN-3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175292
    EGFR WT/T790M-IN-3

    		EGFR Microtubule/Tubulin Cancer
    EGFR WT/T790M-IN-3 is an irreversible covalent EGFR WT and EGFR T790M inhibitor with IC50s value of 28.1 and 24.6 nM. EGFR WT/T790M-IN-3 hampers tubulin polymerization through IC50 value of 5.1 μM. EGFR WT/T790M-IN-3 shows significant anti-proliferative effects on HCT116 and T47D cells, with IC50 values of 3.12 and 4.12 μM, respectively. EGFR WT/T790M-IN-3 can be used for the study of cancers such as non-small cell lung cancer, colon cancer and breast cancer .
    EGFR WT/T790M-IN-3

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