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D-Histidine hydrochloride

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (4) Bacterial (3) Endogenous Metabolite (1) Mitochondrial Metabolism (3) Reference Standards (1)
By Research Areas:	Infection (3) Metabolic Disease (3)

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Inhibitors & Agonists

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Peptides

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Natural
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1

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*D-Histidine*	Mitochondrial Metabolism Bacterial	Infection Metabolic Disease
D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

HY-W017007SB

*3-Methyl-D-histidine-d3 hydrochloride*	Endogenous Metabolite	Others
3-Methyl-D-histidine-d₃ hydrochloride is the deuterium labeled 3-Methyl-D-histidine hydrochloride. 3-Methyl-D-histidine hydrochloride can be found in actin and myosin and is a derivative of histidine .

(tert-Butoxycarbonyl)-D-histidine	Amino Acid Derivatives	Others
(tert-Butoxycarbonyl)-D-histidine is a histidine derivative .

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-histidine	Amino Acid Derivatives	Others
(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-histidine is a histidine derivative .

Boc-D-His(Trt)-OH	Amino Acid Derivatives	Others
N-[(1,1-Dimethylethoxy)carbonyl]-1-(triphenylmethyl)-D-histidine is a histidine derivative .

HY-W012572A

D-Histidine hydrochloride hydrate	Mitochondrial Metabolism Bacterial	Infection Metabolic Disease
D-Histidine hydrochloride hydrate is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine hydrochloride hydrate works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine hydrochloride hydrate downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine hydrochloride hydrate is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

HY-W012572R

D-Histidine (Standard)	Reference Standards Mitochondrial Metabolism Bacterial	Infection Metabolic Disease
D-Histidine (Standard) is the analytical standard of D-Histidine (HY-W012572). This product is intended for research and analytical applications. D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

D-Histidine monohydrochloride	Amino Acid Derivatives	Others
D-Histidine monohydrochloride is a histidine derivative .

Cat. No.	Product Name	Target	Research Area

(tert-Butoxycarbonyl)-D-histidine	Amino Acid Derivatives	Others
(tert-Butoxycarbonyl)-D-histidine is a histidine derivative .

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-histidine	Amino Acid Derivatives	Others
(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-histidine is a histidine derivative .

Boc-D-His(Trt)-OH	Amino Acid Derivatives	Others
N-[(1,1-Dimethylethoxy)carbonyl]-1-(triphenylmethyl)-D-histidine is a histidine derivative .

HY-W012572A

D-Histidine hydrochloride hydrate	Mitochondrial Metabolism Bacterial	Infection Metabolic Disease
D-Histidine hydrochloride hydrate is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine hydrochloride hydrate works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine hydrochloride hydrate downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine hydrochloride hydrate is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

D-Histidine monohydrochloride	Amino Acid Derivatives	Others
D-Histidine monohydrochloride is a histidine derivative .

Cat. No.	Product Name	Category	Target	Chemical Structure

*D-Histidine*	Microorganisms Source classification	Mitochondrial Metabolism Bacterial
D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

HY-W012572R

D-Histidine (Standard)	Microorganisms Source classification	Reference Standards Mitochondrial Metabolism Bacterial
D-Histidine (Standard) is the analytical standard of D-Histidine (HY-W012572). This product is intended for research and analytical applications. D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

Cat. No.	Product Name	Chemical Structure

HY-W017007SB

*3-Methyl-D-histidine-d3 hydrochloride*
3-Methyl-D-histidine-d₃ hydrochloride is the deuterium labeled 3-Methyl-D-histidine hydrochloride. 3-Methyl-D-histidine hydrochloride can be found in actin and myosin and is a derivative of histidine .

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