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Coenzyme A (Standard)

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34

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1

Biochemical Assay Reagents

21

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0111R
    Coenzyme Q10 (Standard)

    CoQ10 (Standard); Ubiquinone-10 (Standard); Ubidecarenone (Standard)

    		 Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Coenzyme Q10 (Standard) is the analytical standard of Coenzyme Q10. This product is intended for research and analytical applications. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10 (Standard)
  • HY-B1391R
    D-Panthenol (Standard)

    Dexpanthenol (Standard)

    		 Reference Standards Endogenous Metabolite Inflammation/Immunology Cancer
    D-Panthenol (Standard) is the analytical standard of D-Panthenol. This product is intended for research and analytical applications. D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. D-panthenol exhibits nephroprotective effect in AKI, promotes tissue repair and regeneration.
    D-Panthenol (Standard)
  • HY-B0511R
    Biotin (Standard)

    Vitamin B7 (Standard); Vitamin H (Standard); D-Biotin (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .
    Biotin (Standard)
  • HY-128851R
    Coenzyme A (Standard)

    		Reference Standards Fatty Acid Synthase (FASN) Endogenous Metabolite Metabolic Disease Cancer
    Coenzyme A (Standard) is the analytical standard of Coenzyme A. This product is intended for research and analytical applications. Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].
    Coenzyme A (Standard)
  • HY-101415R
    Coenzyme Q9 (Standard)

    Ubiquinone Q9 (Standard); CoQ9 (Standard); Ubiquinone 9 (Standard)

    		 Reference Standards Apoptosis Endogenous Metabolite Cardiovascular Disease
    Coenzyme Q9 (Standard) is the analytical standard of Coenzyme Q9. This product is intended for research and analytical applications. Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .
    Coenzyme Q9 (Standard)
  • HY-135753R
    Sethoxydim (Standard)

    BAS 9052 (Standard)

    		 Reference Standards Acetyl-CoA Carboxylase Others
    Sethoxydim (Standard) is the analytical standard of Sethoxydim. This product is intended for research and analytical applications. Sethoxydim is a postemergent herbicide. Sethoxydim inhibits plant acetyl-coenzyme A carboxylase (ACCase) activity .
    Sethoxydim (Standard)
  • HY-B0861R
    Cyhalofop-butyl (Standard)

    		Herbicide Reference Standards Others
    Cyhalofop-butyl (Standard) is the analytical standard of Cyhalofop-butyl. This product is intended for research and analytical applications. Cyhalofop-butyl is a post-emergence herbicide. Cyhalofop-butyl inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis .
    Cyhalofop-butyl (Standard)
  • HY-112790R
    Adenosylcobalamin (Standard)

    Coenzyme B12 (Standard); Cobamamide (Standard); AdoCbl (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    Adenosylcobalamin (Standard) is the analytical standard of Adenosylcobalamin. This product is intended for research and analytical applications. Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase
    Adenosylcobalamin (Standard)
  • HY-101873R
    Atorvastatin lactone (Standard)

    		Reference Standards HMG-CoA Reductase (HMGCR) Metabolic Disease Inflammation/Immunology
    Atorvastatin lactone (Standard) is the analytical standard of Atorvastatin lactone. This product is intended for research and analytical applications. Atorvastatin lactone is a proagent form of atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor .
    Atorvastatin lactone (Standard)
  • HY-126050R
    (R)-Pantetheine (Standard)

    Pantetheine (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    (R)-Pantetheine (Standard) is the analytical standard of (R)-Pantetheine. This product is intended for research and analytical applications. (R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA). (R)-Pantetheine has high toxicity .
    (R)-Pantetheine (Standard)
  • HY-B0430AR
    D-Pantothenic acid sodium (Standard)

    Sodium pantothenate (Standard); Vitamin B5 sodium (Standard)

    		 Reference Standards Apoptosis Endogenous Metabolite Metabolic Disease
    D-Pantothenic acid (sodium) (Standard) is the analytical standard of D-Pantothenic acid (sodium). This product is intended for research and analytical applications. D-Pantothenic acid sodium (Sodium pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid sodium plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1].
    D-Pantothenic acid sodium (Standard)
  • HY-B1856R
    Haloxyfop (Standard)

    		Reference Standards Acetyl-CoA Carboxylase Cancer
    Haloxyfop (Standard) is the analytical standard of Haloxyfop. This product is intended for research and analytical applications. Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC50 of 0.5 μM, but has no effect on this enzyme in pea .
    Haloxyfop (Standard)
  • HY-113076R
    Thiamine pyrophosphate (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    Thiamine pyrophosphate (Standard) is the analytical standard of Thiamine pyrophosphate. This product is intended for research and analytical applications. Thiamine pyrophosphate is the coenzyme form of Vitamin B1, and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases .
    Thiamine pyrophosphate (Standard)
  • HY-B0456R
    Riboflavin (Standard)

    Vitamin B2 (Standard); E101 (Standard)

    		 Reference Standards Endogenous Metabolite Bacterial Metabolic Disease Cancer
    Riboflavin (Standard) is the analytical standard of Riboflavin. This product is intended for research and analytical applications. Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .
    Riboflavin (Standard)
  • HY-W010735R
    ATP disodium salt hydrate (Standard)

    Adenosine 5'-triphosphate disodium salt hydrate (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP (disodium salt hydrate) (Standard) is the analytical standard of ATP (disodium salt hydrate). This product is intended for research and analytical applications. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .
    ATP disodium salt hydrate (Standard)
  • HY-100399AR
    Nevanimibe hydrochloride (Standard)

    PD-132301 hydrochloride (Standard); ATR101 hydrochloride (Standard)

    		 Reference Standards Acyltransferase Apoptosis Cancer
    Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer .
    Nevanimibe hydrochloride (Standard)
  • HY-138247R
    β-Lactamase-IN-2 (Standard)

    EX-A4764 (Standard); UUN51204 (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Infection
    ATP (disodium salt) (Standard) is the analytical standard of ATP (disodium salt). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
    β-Lactamase-IN-2 (Standard)
  • HY-B2176BR
    ATP dimagnesium (Standard)

    		Endogenous Metabolite Inflammation/Immunology
    ATP (dimagnesium) (Standard) is the analytical standard of ATP (dimagnesium). This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation .
    ATP dimagnesium (Standard)
  • HY-13215R
    Avasimibe (Standard)

    		Acyltransferase Cancer
    Avasimibe (Standard) is the analytical standard of Avasimibe. This product is intended for research and analytical applications. Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer .
    Avasimibe (Standard)
  • HY-B0345AR
    ATP disodium (Standard)

    Adenosine 5'-triphosphate disodium (Standard); Disodium adenosine triphosphate (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP disodium salt (Standard) is the analytical standard of ATP disodium salt (HY-B0345A). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
    ATP disodium (Standard)
  • HY-W008646R
    7,8-Dihydro-L-biopterin (Standard)

    		Reference Standards Endogenous Metabolite Others
    NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
    7,8-Dihydro-L-biopterin (Standard)
  • HY-B2176AR
    ATP disodium trihydrate (Standard)

    		Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP (disodium trihydrate) (Standard) is the analytical standard of ATP (disodium trihydrate). This product is intended for research and analytical applications. ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
    ATP disodium trihydrate (Standard)
  • HY-F0001R
    NADH disodium salt (Standard)

    Disodium NADH (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
    NADH disodium salt (Standard)
  • HY-W012575R
    2,4-Dihydroxybenzoic acid (Standard)

    		Reference Standards Reactive Oxygen Species (ROS) Inflammation/Immunology
    2,4-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,4-Dihydroxybenzoic acid (HY-W012575). This product is intended for research and analytical applications. 2,4-Dihydroxybenzoic acid is a degradation product of acid cherry anthocyanins during in vitro cell culture and an analogue of coenzyme Q precursor molecules. 2,4-Dihydroxybenzoic acid can improve the related symptoms of kidney diseases caused by ADCK4/Coq6 deficiency .
    2,4-Dihydroxybenzoic acid (Standard)
  • HY-17379R
    Atorvastatin hemicalcium salt (Standard)

    CI-981 (Standard); Atorvastatin hemicalcium (Standard)

    		 Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis Metabolic Disease Inflammation/Immunology Cancer
    Atorvastatin (hemicalcium salt) (Standard) is the analytical standard of Atorvastatin (hemicalcium salt). This product is intended for research and analytical applications. Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium salt inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively .
    Atorvastatin hemicalcium salt (Standard)
  • HY-B0968AR
    Trimetazidine (Standard)

    		Reference Standards Autophagy Cardiovascular Disease
    Trimetazidine (Standard) is the analytical standard of Trimetazidine. This product is intended for research and analytical applications. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
    Trimetazidine (Standard)
  • HY-B0968R
    Trimetazidine dihydrochloride (Standard)
    4 Publications Verification

    		 Reference Standards Autophagy Cardiovascular Disease
    Trimetazidine (dihydrochloride) (Standard) is the analytical standard of Trimetazidine (dihydrochloride). This product is intended for research and analytical applications. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
    Trimetazidine dihydrochloride (Standard)
  • HY-107572R
    PD 128042 (Standard)

    		Acyltransferase Metabolic Disease
    PD 128042 (Standard) is the analytical standard of PD 128042. This product is intended for research and analytical applications. PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway .
    PD 128042 (Standard)
  • HY-W011727AR
    Pyridoxal 5'-?phosphate monohydrate (Standard)

    Pyridoxal phosphate monohydrate (Standard)

    		 Reference Standards Endogenous Metabolite Amyloid-β ERK Neurological Disease Metabolic Disease Cancer
    Pyridoxal 5'-​phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-​phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
    Pyridoxal 5'-?phosphate monohydrate (Standard)
  • HY-N1511R
    Ganoderic acid D (Standard)

    		Reference Standards Sirtuin Apoptosis Cancer
    Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
    Ganoderic acid D (Standard)
  • HY-F0002R
    NADP sodium salt (Standard)

    Sodium NADP (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease Inflammation/Immunology Cancer
    NADP (sodium salt) (Standard) is the analytical standard of NADP (sodium salt). This product is intended for research and analytical applications. NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes[1][4].
    NADP sodium salt (Standard)
  • HY-N0303R
    Idebenone (Standard)

    		Reference Standards Mitochondrial Metabolism Apoptosis Neurological Disease
    Idebenone (Standard) is the analytical standard of Idebenone. This product is intended for research and analytical applications. Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM) . Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells . Idebenone quickly crosses the blood-brain barrier.
    Idebenone (Standard)
  • HY-F0002AR
    NADP disodium salt (Standard)

    		Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    NADP (disodium salt) (Standard) is the analytical standard of NADP (disodium salt). This product is intended for research and analytical applications. NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
    NADP disodium salt (Standard)
  • HY-B2176R
    ATP (Standard)

    Adenosine 5'-triphosphate (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation . In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs .
    ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner .
    ATP promotes neutrophil chemotaxis in vitro .
    In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo .
    ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo .
    ATP (Standard)

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