2. Others Metabolic Enzyme/Protease Apoptosis
  3. Reference Standards Acyltransferase Apoptosis
  4. Nevanimibe hydrochloride (Standard)

Nevanimibe hydrochloride (Standard)  (Synonyms: PD-132301 hydrochloride (Standard); ATR101 hydrochloride (Standard))

Cat. No.: HY-100399AR Purity: ≥98%
Handling Instructions Technical Support

Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer.

For research use only. We do not sell to patients.

Nevanimibe hydrochloride (Standard) Chemical Structure

Nevanimibe hydrochloride (Standard) Chemical Structure

CAS No. : 133825-81-7

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Description
Molecular Weight

458.08

Formula

C27H40ClN3O
CAS No.
SMILES

O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Nevanimibe hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nevanimibe hydrochloride (Standard)133825-81-7PD-132301 hydrochloride (Standard)ATR101 hydrochloride (Standard)Reference StandardsAcyltransferaseApoptosisDiacylglycerol acyltransferaseDiglyceride acyltransferaseacyl-CoA:cholesterol acyltransferasemono- acylglycerol acyltransferaseorallyactiveacyl-coenzymeA:cholesterolO-acyltransferase1adrenocorticalcancerInhibitorinhibitorinhibit

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