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Results for "

Cleavable fluorescent probe

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fluorescent Dye (11) Photosensitizer (1)
By Research Areas:	Cancer (5)

Inhibitors & Agonists

Fluorescent Dye

Targets Recommended: Fluorescent Dye

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-126561

Green CMFDA 5+ Cited Publications CMFDA	Fluorescent Dye	Others
Green CMFDA is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .

HY-D0717

DAF-FM DA 10+ Cited Publications Diaminofluorescein-FM diacetate	Fluorescent Dye	Cancer
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .

HY-D2930

BG-SS-SulfoCy5 SNAP-SS-SulfoCy5	Fluorescent Dye	Others
BG-SS-SulfoCy5 is a SulfoCy5-labeled SNAP tag fluorescent probe, linked by a disulfide bond (Ex/Em: 649 nm/666 nm). BG-SS-SulfoCy5 combines the specific recognition of SNAP-tag, the cleavability of disulfide bond, and the excellent optical properties of SulfoCy5. BG-SS-SulfoCy5 can be used for tracking the internalization of cell surface proteins and multiple labeling experiments .

HY-149931

BMV109	Fluorescent Dye	Cancer
BMV109 is a quenched probe that becomes fluorescent when cleaved and covalently bound by active cathepsin proteases. BMV109 can be exploited for tumor imaging .

HY-DY1046

Green CMFDA (solution)	Fluorescent Dye	Others
Green CMFDA (solution) is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope . Solution Concentration: 10 mM

HY-112526

Thiofluor 623	Fluorescent Dye	Others
Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .

HY-DY1048

DAF-FM DA (solution)	Fluorescent Dye	Cancer
DAF-FM DA (Diaminofluorescein-FM diacetate) (solution) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) . Solution Concentration: 2 mM

HY-155486

HCy-AAN-Bio	Fluorescent Dye	Cancer
HCy-AAN-Bio is a tumor-targeted hemicyanine (HCy) probe for Fluorescent/photoacoustic (FL/PA) imaging of legumain in vivo. Legumain can specifically cleave HCy-AAN-Bio with the generation of FL/PA signal. HCy-AAN-Bio is a powerful tool for early diagnosis of associated cancer .

HY-W411215

1,4-Diacetoxy-2,3-dicyanobenzene	Fluorescent Dye	Others
1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .

HY-175163

TPAPyN	Photosensitizer	Cancer
TPAPyN is a nitroreductase(NTR)-responsive type I photosensitizer. TPAPyN facilitates the imaging of hypoxic cancer cells and image-guided photodynamic therapy (PDT). TPAPyN does not emit fluorescence in the aqueous environment, but restores when NTR cleaves the nitrofuran quencher with aggregation-induced emission. TPAPyN can be used as a fluorescent probe for specific imaging of hypoxic cancer .

HY-D2924

CBG-549-QSY7	Fluorescent Dye	Others
CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation .

HY-D2943

BG-SS-SulfoCy3 SNAP-SS-SulfoCy3	Fluorescent Dye	Others
BG-SS-SulfoCy3 is a SulfoCy3-labeled SNAP tag fluorescent probe, which is linked by a disulfide bond to achieve selective labeling and controllable cleavage. BG-SS-SulfoCy3 can be used to study the endocytosis and trafficking of membrane proteins such as GPCRs .

Cat. No.	Product Name	Type

HY-126561

Green CMFDA 5+ Cited Publications CMFDA	Fluorescent Dye
Green CMFDA is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .

HY-D0717

DAF-FM DA 10+ Cited Publications Diaminofluorescein-FM diacetate	Fluorescent Dye
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .

HY-D2930

BG-SS-SulfoCy5 SNAP-SS-SulfoCy5	Fluorescent Dye
BG-SS-SulfoCy5 is a SulfoCy5-labeled SNAP tag fluorescent probe, linked by a disulfide bond (Ex/Em: 649 nm/666 nm). BG-SS-SulfoCy5 combines the specific recognition of SNAP-tag, the cleavability of disulfide bond, and the excellent optical properties of SulfoCy5. BG-SS-SulfoCy5 can be used for tracking the internalization of cell surface proteins and multiple labeling experiments .

HY-DY1046

Green CMFDA (solution)	Fluorescent Dye
Green CMFDA (solution) is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope . Solution Concentration: 10 mM

HY-112526

Thiofluor 623	Fluorescent Dye
Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .

Thiofluor 623

Fluorescent Dye

Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .

HY-DY1048

DAF-FM DA (solution)	Fluorescent Dye
DAF-FM DA (Diaminofluorescein-FM diacetate) (solution) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) . Solution Concentration: 2 mM

HY-W411215

1,4-Diacetoxy-2,3-dicyanobenzene	Fluorescent Dye
1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .

HY-D2924

CBG-549-QSY7	Fluorescent Dye
CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation .

CBG-549-QSY7

Fluorescent Dye

CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation .

HY-D2943

BG-SS-SulfoCy3 SNAP-SS-SulfoCy3	Fluorescent Dye
BG-SS-SulfoCy3 is a SulfoCy3-labeled SNAP tag fluorescent probe, which is linked by a disulfide bond to achieve selective labeling and controllable cleavage. BG-SS-SulfoCy3 can be used to study the endocytosis and trafficking of membrane proteins such as GPCRs .

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