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Carboxylic acid metabolite

" in MedChemExpress (MCE) Product Catalog:

49

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9

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7

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131669
    Dasatinib metabolite M6

    Dasatinib Carboxylic acid

    		 Drug Metabolite Others Cancer
    Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib (HY-10181). Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor .
    Dasatinib metabolite M6
  • HY-G0023
    Niraparib metabolite M1

    Niraparib Carboxylic acid metabolite M1; M1 metabolite of niraparib

    		 Drug Metabolite Others
    Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.
    Niraparib metabolite M1
  • HY-30004S
    1-Aminocyclopropane-1-carboxylic acid-d4

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    1-Aminocyclopropane-1-carboxylic acid-d4 is the deuterium labeled 1-Aminocyclopropane-1-carboxylic acid. Aminocyclopropane-1-carboxylic acid is an endogenous metabolite[1].
    1-Aminocyclopropane-1-carboxylic acid-d4
  • HY-70002BS
    Enzalutamide carboxylic acid-d6

    MDV3100 Carboxylic acid-d6

    		 Autophagy Androgen Receptor Isotope-Labeled Compounds Cancer
    Enzalutamide carboxylic acid-d6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide .
    Enzalutamide carboxylic acid-d6
  • HY-G0024A
    Vildagliptin carboxylic acid metabolite TFA

    Vildagliptin carboxy acid metabolite TFA

    		 Cytochrome P450 Metabolic Disease
    Vildagliptin carboxylic acid metabolite (M20.7) TFA is a potent P450 enzyme activity inhibitor .
    Vildagliptin carboxylic acid metabolite TFA
  • HY-135500
    ACT-373898

    		Endothelin Receptor Endocrinology
    ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist .
    ACT-373898
  • HY-148377
    Abiraterone sulfate N-oxide

    		Drug Metabolite Cancer
    Abiraterone sulfate N-oxide is a carboxylic acid. Abiraterone sulfate N-oxide also is a major metabolite of Abiraterone (HY-70013). Abiraterone sulfate N-oxide can be used for the research of prostate cancer .
    Abiraterone sulfate N-oxide
  • HY-N15754
    3-Hydroxy-2-methylglutaric acid

    		Drug Metabolite Metabolic Disease Inflammation/Immunology Endocrinology Cancer
    3-Hydroxy-2-methylglutaric acid is a carboxylic acid metabolite. 3-Hydroxy-2-methylglutaric acid can be isolated from the flower Veronica incana L. 3-Hydroxy-2-methylglutaric acid can be used for upper respiratory tract diseases, malignant neoplasms, gastrointestinal tract and genitourinary system disorders and diabetes mellitus research .
    3-Hydroxy-2-methylglutaric acid
  • HY-G0023R
    Niraparib metabolite M1 (Standard)

    Niraparib Carboxylic acid metabolite M1 (Standard); M1 metabolite of niraparib (Standard)

    		 Reference Standards Drug Metabolite Others
    Berberine (hemisulfate) (Standard) is the analytical standard of Berberine (hemisulfate). This product is intended for research and analytical applications. Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
    Niraparib metabolite M1 (Standard)
  • HY-75087S
    (R)-Pyrrolidine-2-carboxylic acid-d3

    (+)-(R)-Proline-d3; (R)-(+)-Proline-d3; (R)-2-Carboxypyrrolidine-d3; (R)-Proline-d3

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    (R)-Pyrrolidine-2-carboxylic acid-d3 is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.
    (R)-Pyrrolidine-2-carboxylic acid-d3
  • HY-Z12431
    Silodosin carboxylic acid impurity

    KMD-3293

    		 Endogenous Metabolite Metabolic Disease
    Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia .
    Silodosin carboxylic acid impurity
  • HY-76210
    5-Hydroxypyrazine-2-Carboxylic Acid
    1 Publications Verification

    		 Bacterial Antibiotic Others
    5-Hydroxypyrazine-2-Carboxylic Acid, a metabolite of anti-tuberculosis drug pyrazinamide (PZA).
    5-Hydroxypyrazine-2-Carboxylic Acid
  • HY-N1272
    Secaubryenol

    		Endogenous Metabolite Others
    Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 μg/mL .
    Secaubryenol
  • HY-40161R
    Indole-3-carboxylic acid (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    Indole-3-carboxylic acid (Standard) is the analytical standard of Indole-3-carboxylic acid. This product is intended for research and analytical applications. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases .
    Indole-3-carboxylic acid (Standard)
  • HY-70002B
    Enzalutamide carboxylic acid
    2 Publications Verification

    MDV3100 Carboxylic acid

    		 Drug Metabolite Cancer
    Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist .
    Enzalutamide carboxylic acid
  • HY-40161S
    Indole-3-carboxylic acid-d4

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Indole-3-carboxylic acid-d4 is deuterium labeled Indole-3-carboxylic acid. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases .
    Indole-3-carboxylic acid-d4
  • HY-W740380
    21-Carboxylic acid triamcinolone acetonide

    		Drug Metabolite Others
    21-Carboxylic acid triamcinolone acetonide is a metabolite produced in the body after oral administration of [14C]-triamcinolone acetonide .
    21-Carboxylic acid triamcinolone acetonide
  • HY-W725295
    1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid

    		Opioid Receptor Neurological Disease
    1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid is structurally similar to known synthetic cannabinoid metabolites.
    1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid
  • HY-40161
    Indole-3-carboxylic acid
    2 Publications Verification

    		 Endogenous Metabolite Bacterial Metabolic Disease Cancer
    Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease research .
    Indole-3-carboxylic acid
  • HY-134234R
    Celecoxib carboxylic acid (Standard)

    		COX Others
    Celecoxib carboxylic acid (Standard) is the analytical standard of Celecoxib carboxylic acid. This product is intended for research and analytical applications. Celecoxib carboxylic acid is a metabolite of celecoxib (HY-14398). Celecoxib is a selective COX-2 inhibitor with an IC50 of 40 nM .
    Celecoxib carboxylic acid (Standard)
  • HY-145991R
    Ribavirin carboxylic acid (Standard)

    		Reference Standards Drug Metabolite Infection
    Ribavirin carboxylic acid (Standard) is the analytical standard of Ribavirin carboxylic acid. This product is intended for research and analytical applications. Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity .
    Ribavirin carboxylic acid (Standard)
  • HY-66035
    4-(Trifluoromethyl)nicotinic acid

    4-(Trifluoromethyl)pyridine-3-Carboxylic acid

    		 Parasite Infection
    4-(Trifluoromethyl)nicotinic acid (4-(Trifluoromethyl)pyridine-3-carboxylic acid) is a metabolite of the pyridinecarboxamide insecticide Flonicamid (HY-119649) .
    4-(Trifluoromethyl)nicotinic acid
  • HY-175659
    Dabrafenib carboxylic acid

    		Endogenous Metabolite Others
    Dabrafenib carboxylic acid is the carboxyl metabolite of dabrafenib (HY-14660) .
    Dabrafenib carboxylic acid
  • HY-W354369
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid

    		Mas-related G-protein-coupled Receptor (MRGPR) Inflammation/Immunology
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid is a MRGPRX4 antagonist (IC50: >2.5 μM) .
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
  • HY-I0177
    Vilazodone carboxylic acid

    		Drug Metabolite Others
    Vilazodone carboxylic acid is a vilazodone metabolite observed in both urine (major) and plasma (minor) .
    Vilazodone carboxylic acid
  • HY-141749AS
    Clopidogrel carboxylic acid-d4

    CLPM-d4; SR 26334-d4

    		 Isotope-Labeled Compounds Cardiovascular Disease
    Clopidogrel carboxylic acid-d4 is a deuterated derivative of Clopidogrel carboxylic acid, which is an inactive metabolite of the antiplatelet agent Clopidogrel (HY-15283) in plasma. Clopidogrel carboxylic acid-d4 can be used to further explore the metabolic characteristics of Clopidogrel .
    Clopidogrel carboxylic acid-d4
  • HY-W158239
    4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid

    		Drug Metabolite Others
    4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid is a metabolite of GW 501516 (HY-10838) .
    4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid
  • HY-131314
    Ibuprofen carboxylic acid

    		Drug Metabolite Others
    Ibuprofen carboxylic acid is the metabolite of Ibuprofen (HY-78131), that has high concentrations in wastewater and water environments, and disappears fast during biodegradation, compared to the other ibuprofen metabolite .
    Ibuprofen carboxylic acid
  • HY-N16371
    6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid

    		Endogenous Metabolite Inflammation/Immunology Cancer
    6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid (Compound MC-1), an isocoumarin, is a metabolite of Cytogenin (HY-19606). 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid has anti-angiogenic activity in S-180 implanted dorsal air sac mice model. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid also modifies collagen-induced arthritis. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid can be used for cancers and inflammatory diseases research .
    6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid
  • HY-W591818
    Sunitinib carboxylic acid

    		Drug Derivative Cancer
    Sunitinib carboxylic acid is a carboxylic acid metabolite of Sunitinib (HY-10255A). Sunitinib is a multi-target tyrosine kinase inhibitor, mainly used to inhibit malignant tumors such as gastrointestinal stromal tumors, renal cell carcinoma, and pancreatic neuroendocrine tumors .
    Sunitinib carboxylic acid
  • HY-134234
    Celecoxib carboxylic acid

    		COX Others
    Celecoxib carboxylic acid is a metabolite of celecoxib (HY-14398). Celecoxib is a selective COX-2 inhibitor with an IC50 of 40 nM .
    Celecoxib carboxylic acid
  • HY-145991
    Ribavirin carboxylic acid

    		Drug Metabolite Infection
    Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity .
    Ribavirin carboxylic acid
  • HY-141749A
    Clopidogrel carboxylic acid

    CLPM; SR 26334

    		 Endogenous Metabolite Metabolic Disease
    Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum .
    Clopidogrel carboxylic acid
  • HY-12765S1
    Losartan carboxylic acid-d4 hydrochloride

    		Isotope-Labeled Compounds Angiotensin Receptor Cardiovascular Disease
    Losartan carboxylic acid-d4 (hydrochloride) is deuterium labeled Losartan Carboxylic Acid. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure .
    Losartan carboxylic acid-d4 hydrochloride
  • HY-12765R
    Losartan Carboxylic Acid (Standard)

    E-3174 (Standard); EXP-3174 (Standard)

    		 Drug Metabolite Reference Standards Angiotensin Receptor Cardiovascular Disease
    Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure [4].
    Losartan Carboxylic Acid (Standard)
  • HY-141749B
    Clopidogrel carboxylic acid hydrochloride

    CLPM hydrochloride; SR 26334 hydrochloride

    		 Drug Metabolite Cardiovascular Disease
    Clopidogrel carboxylic acid (CLPM) hydrochloride is an inactive metabolite of the widely used antiplatelet medication clopidogrel, which serves as a reference standard for quantitative analysis of clopidogrel metabolism. Clopidogrel carboxylic acid hydrochloride has been shown to represent approximately 85% of circulating clopidogrel, hydrolyzed from the active form by esterases. Clopidogrel carboxylic acid hydrochloride plays a crucial role in assessing the pharmacokinetics and bioavailability of clopidogrel in various clinical and research settings.
    Clopidogrel carboxylic acid hydrochloride
  • HY-30004
    1-Aminocyclopropane-1-carboxylic acid

    		Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity. .
    1-Aminocyclopropane-1-carboxylic acid
  • HY-121029
    Bisegliptin

    KRP-104

    		 Histone Methyltransferase Metabolic Disease
    Bisegliptin (KRP-104) is a small molecule compound with antidiabetic activity. Bisegliptin is metabolized mainly by converting the cyano group to the carboxylic acid form, and DPP-4 plays a partial role in its metabolism. The carboxylic acid metabolite of bisegliptin can be detected both in vivo and in vitro. In rat experiments, the plasma concentration of the carboxylic acid metabolite of bisegliptin was affected by other DPP inhibitors, showing the complexity of its metabolic process. The amide intermediate of bisegliptin was detected both in vivo and in vitro, and its conversion rate was significantly faster than that of the parent compound when incubated with DPP-4 .
    Bisegliptin
  • HY-12765S
    Losartan-d4 (carboxylic acid)

    E-3174 d4; EXP-3174 d4

    		 Angiotensin Receptor Cardiovascular Disease Endocrinology Cancer
    Losartan-d4 carboxylic acid (E-3174-d4) is the deuterium labeled Losartan Carboxylic Acid (HY-12765). Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure.
    Losartan-d4 (carboxylic acid)
  • HY-W002065
    4-Carboxypyrazole

    		Drug Metabolite Drug Intermediate Cancer
    4-Carboxypyrazole (1H-Pyrazole-4-carboxylic acid) is a metabolite of Fomepizole (HY-B0876). 4-Carboxypyrazole is involved in the synthesis of ALKBH1 inhibitors. 4-Carboxypyrazole can be used in the research of gastric cancer .
    4-Carboxypyrazole
  • HY-30004R
    1-Aminocyclopropane-1-carboxylic acid (Standard)

    		Reference Standards Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    1-Aminocyclopropane-1-carboxylic acid (Standard) is the analytical standard of 1-Aminocyclopropane-1-carboxylic acid. This product is intended for research and analytical applications. 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity. .
    1-Aminocyclopropane-1-carboxylic acid (Standard)
  • HY-12765
    Losartan Carboxylic Acid

    E-3174; EXP-3174

    		 Drug Metabolite Angiotensin Receptor Cardiovascular Disease
    Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure .
    Losartan Carboxylic Acid
  • HY-W403633
    Hexahydrohippuric acid

    		Bacterial Infection
    Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity .
    Hexahydrohippuric acid
  • HY-135895
    Detomidine carboxylic acid

    		Adrenergic Receptor Neurological Disease Endocrinology
    Detomidine carboxylic acid is the major urinary metabolite of Detomidine. Detomidine is a synthetic α2-adrenergic agonist. Detomidine also has cardiac and respiratory effects and an antidiuretic action .
    Detomidine carboxylic acid
  • HY-W741575
    Iloperidone carboxylic acid

    P95-12113

    		 5-HT Receptor Adrenergic Receptor Dopamine Receptor Neurological Disease
    Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone (HY-17410). Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pKi of 8.15, and moderate affinity for adrenergic receptor α1/α2B/α2C .
    Iloperidone carboxylic acid
  • HY-117923
    PF-06465603

    		mTOR PI3K Cancer
    PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure .
    PF-06465603
  • HY-136410
    4-hydroxy Nonenal Mercapturic Acid

    		Endogenous Metabolite Metabolic Disease
    4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
    4-hydroxy Nonenal Mercapturic Acid
  • HY-34439
    2,5-Dimethylpyrazine

    NSC 49139

    		 Endogenous Metabolite Metabolic Disease
    2,5-Dimethylpyrazine (NSC 49139) is an endogenous metabolite. 2,5-Dimethylpyrazine in produced in food systems of two whey protein hydrolysates, obtained using either trypsin or proteinase from Aspergillus melleus. 2,5-Dimethylpyrazine can be qualitatively monitored using a stable isotope dilution assay. 2,5-Dimethylpyrazine can also be generated via microbial mechanisms using Bacillus subtilis. 2,5-Dimethylpyrazine can be oxidized to form 5-methylpyrazine-2-carboxylic acid, which is the intermediate in the synthesis of antilipoltic agent. 2,5-Dimethylpyrazine is a volatile compound that can give a roasted peanut flavor .
    2,5-Dimethylpyrazine
  • HY-157129
    AMPK-α1β1γ1 activator 1

    		AMPK Cardiovascular Disease
    AMPK-α1β1γ1 activator 1 (M1) is an acyl glucuronide metabolite of Indole-3-carboxylic Acid-based AMPK activator. AMPK-α1β1γ1 activator 1 can selectively activated human β1 isoforms with an EC50 value of 38.1nM. AMPK-α1β1γ1 activator 1 can direct binding with human AMPK α1β1γ1 isoform. AMPK-α1β1γ1 activator 1 can be used for the research of diabetic nephropathy .
    AMPK-α1β1γ1 activator 1

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