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Results for "

Caesalpinia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Antibiotic (1) Apoptosis (4) Bacterial (1) Influenza Virus (3) Interleukin Related (2) JAK (1) p38 MAPK (1) Parasite (1) Reference Standards (1) SARS-CoV (1) STAT (1) TNF Receptor (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (4) Infection (7) Inflammation/Immunology (7) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2949

Bonducellpin D	SARS-CoV	Infection Cancer
Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. Bonducellpin D exhibits broad-spectrum inhibition potential against SARS-CoV M ^pro and MERS-CoV M ^pro, with an K_i of 467.11 and 284.86 nM, respectively. Bonducellpin D also exhibits moderate anti-cancer activity in vitro .

HY-N2735

7,3',4'-Trihydroxy-3-benzyl-2H-chromene	Influenza Virus	Infection Inflammation/Immunology
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC₅₀ values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .

HY-N2981

Caesalmin B	Antibiotic	Infection
Caesalmin B is a furanoditerpenoid lactone isolated from Caesalpinia minax. Caesalmin B exhibits antiviral activity .

HY-133225

Caesalpine A	Others	Others
Caesalpine A, a cassane-type diterpene, is a natural product that could be isolated from the seeds of Caesalpinia minax .

HY-N2753

7-Acetoxybonducellpin C	Parasite	Infection
7-Acetoxybonducellpin C, a diterpenoid, is a nature product that could be isolated from the seed kernels of Caesalpinia crista. 7-Acetoxybonducellpin C has antimalarial activity .

HY-133224

Caesalpine B	Others	Others
Caesalpine B is a Diterpenoids product that can be isolated from the seeds of Caesalpinia minax. .

HY-N7551

Neocaesalpin L	Others	Others
Neocaesalpin L is a Diterpenoids product that can be isolated from the herbs of Caesalpinia minax HANCE. .

HY-N3449

Isovouacapenol C	Others	Others
Isovouacapenol C is a Diterpenoids product that can be isolated from the roots of Caesalpinia pulcherrima .

HY-N9308

Delta-Caesalpin	Others	Others
Delta-Caesalpin is a Diterpenoids product that can be isolated from the herbs of Caesalpinia pulcherrima. .

HY-N7583

Norcaesalpinin E	Others	Others
Norcaesalpinin E is a natural cassane-type diterpene found in the seed kernels of Caesalpinia crista .

HY-133104

Neocaesalpin O	Others	Others
Neocaesalpin O is a Diterpenoids product that can be isolated from the herbs of Caesalpinia minax HANCE. .

HY-N9049

5-O-Methyldalbergiphenol	Others	Others
5-O-Methyldalbergiphenol is a Phenols product that can be isolated from the heartwoods of Caesalpinia sappan .

HY-N2951

Borapetoside B (-)-Borapetoside B	Others	Others
Borapetoside B ((-)-Borapetoside B) is a Diterpenoids product that can be isolated from the herbs of Caesalpinia minax HANCE. .

HY-N10424

Brazilein	Apoptosis	Inflammation/Immunology
Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes .

HY-138267

7-O-Acetylneocaesalpin N	Others	Others
7-O-Acetylneocaesalpin N is a Diterpenoids product that can be isolated from the seeds of Caesalpinia minax Hance .

HY-N1715

2-Acetoxy-3-deacetoxycaesaldekarin e	Others	Others
2-Acetoxy-3-deacetoxycaesaldekarin e (compound 11) is a furanoditerpene that can be found in Caesalpinia crista .

HY-59001

Sappanchalcone	Apoptosis	Cancer
Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells .

HY-N9315

Episappanol	TNF Receptor Interleukin Related	Inflammation/Immunology
Episappanol is a natural compound isolated from Caesalpinia sappan heartwood with anti-inflammatory activity. Episappanol significantly inhibits the IL-6 and TNF-α secretion .

HY-44135

7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one	Others	Others
7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one, a homoisoflavonoid, can be isolated from the dried heartwood of Caesalpinia sappan .

HY-N9291

4-(trans)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone	Others	Others
4-(trans)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone is a Phenols product that can be isolated from the herbs of Caesalpinia minax. .

HY-N0800

Protosappanin B (-)-Protosappanin B	Apoptosis	Cancer
Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity . Protosappanin B induces apoptosis and causes G₁ cell cycle arrest in human bladder cancer cells .

HY-N0116

Hematoxylin Maximum Cited Publications 8 Publications Verification Natural Black 1; Haematoxylin	Amyloid-β	Others
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC₅₀ of 1.6 μM.

HY-N4299

Caesappanin C	Others	Metabolic Disease
Caesappanin C, a biphenyl dimer from the ethanolic extract of the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro. Caesappanin C has the potential to stimulate bone formation and regeneration .

HY-N10108

Protosappanin A dimethyl acetal	Xanthine Oxidase	Inflammation/Immunology
Protosappanin A dimethyl acetal is a homoisoflavonoid. Protosappanin A dimethyl acetal can be isolated from Caesalpinia sappan. Protosappanin A dimethyl acetal is also a competive inhibitor with significant xanthine oxidase inhibitory activity (IC₅₀=50.7 μM) .

HY-113573

Protosappanin A PTA	Interleukin Related JAK STAT	Inflammation/Immunology
Protosappanin A (PTA), an immunosuppressive ingredient and major biphenyl compound isolated from Caesalpinia sappan L, suppresses JAK2/STAT3-dependent inflammation pathway through down-regulating the phosphorylation of JAK2 and STAT3 .

HY-N0800R

Protosappanin B (Standard) (-)-Protosappanin B (Standard)	Reference Standards Apoptosis	Cancer
Protosappanin B (Standard) is the analytical standard of Protosappanin B. This product is intended for research and analytical applications. Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity . Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells .

HY-N10069

Bonducellin	Bacterial	Infection
Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L) .

HY-N1818

Deoxysappanone B 3-Deoxysappanone B	p38 MAPK	Neurological Disease Inflammation/Immunology
Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage .

HY-N1745A

3-Deoxysappanchalcone 2 Publications Verification	Influenza Virus	Infection Inflammation/Immunology
3-Deoxysappanchalcone is a naturally-occurring chalcone compound found in Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC₅₀ = 1.06 μM) .

HY-N10843

4-O-Methylepisappanol	Influenza Virus	Infection
4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC₅₀ values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively .

Cat. No.	Product Name	Type

HY-N0116

Hematoxylin 5+ Cited Publications Natural Black 1; Haematoxylin	Chromogenic Substrates
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC₅₀ of 1.6 μM.

Bonducellpin D	Other Terpenoids Infection Caesalpinia minax Hance Classification of Application Fields Leguminosae Terpenoids Source classification Plants Disease Research Fields	SARS-CoV
Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. Bonducellpin D exhibits broad-spectrum inhibition potential against SARS-CoV M ^pro and MERS-CoV M ^pro, with an K_i of 467.11 and 284.86 nM, respectively. Bonducellpin D also exhibits moderate anti-cancer activity in vitro .

7,3',4'-Trihydroxy-3-benzyl-2H-chromene	Structural Classification Leguminosae Caesalpinia sappan L. Source classification Phenols Polyphenols Plants	Influenza Virus
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC₅₀ values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .

Caesalmin B	Other Terpenoids Infection Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Plants Disease Research Fields Caesalpinia crista L.	Antibiotic
Caesalmin B is a furanoditerpenoid lactone isolated from Caesalpinia minax. Caesalmin B exhibits antiviral activity .

Caesalpine A	Structural Classification Leguminosae Terpenoids Source classification Diterpenoids Plants Guilandina minax (Hance) G. P. Lewis	Others
Caesalpine A, a cassane-type diterpene, is a natural product that could be isolated from the seeds of Caesalpinia minax .

7-Acetoxybonducellpin C	Structural Classification Leguminosae Caesalpinia crista L. Terpenoids Source classification Diterpenoids Plants	Parasite
7-Acetoxybonducellpin C, a diterpenoid, is a nature product that could be isolated from the seed kernels of Caesalpinia crista. 7-Acetoxybonducellpin C has antimalarial activity .

Caesalpine B	Structural Classification Terpenoids Source classification Diterpenoids Plants Guilandina minax (Hance) G. P. Lewis Fabaceae	Others
Caesalpine B is a Diterpenoids product that can be isolated from the seeds of Caesalpinia minax. .

Neocaesalpin L	Structural Classification Terpenoids Source classification Diterpenoids Plants Fabaceae	Others
Neocaesalpin L is a Diterpenoids product that can be isolated from the herbs of Caesalpinia minax HANCE. .

Isovouacapenol C	Structural Classification Leguminosae Terpenoids Source classification Diterpenoids Plants Artemisia capillaris Thunb.	Others
Isovouacapenol C is a Diterpenoids product that can be isolated from the roots of Caesalpinia pulcherrima .

Delta-Caesalpin	Structural Classification Leguminosae Terpenoids Source classification Diterpenoids Plants Artemisia capillaris Thunb.	Others
Delta-Caesalpin is a Diterpenoids product that can be isolated from the herbs of Caesalpinia pulcherrima. .

Norcaesalpinin E	Structural Classification Leguminosae Caesalpinia crista L. Terpenoids Source classification Diterpenoids Plants	Others
Norcaesalpinin E is a natural cassane-type diterpene found in the seed kernels of Caesalpinia crista .

Neocaesalpin O	Structural Classification Terpenoids Source classification Diterpenoids Plants Guilandina minax (Hance) G. P. Lewis Fabaceae	Others
Neocaesalpin O is a Diterpenoids product that can be isolated from the herbs of Caesalpinia minax HANCE. .

5-O-Methyldalbergiphenol	Structural Classification Xanthones Leguminosae Caesalpinia sappan L. Source classification Phenols Plants	Others
5-O-Methyldalbergiphenol is a Phenols product that can be isolated from the heartwoods of Caesalpinia sappan .

Borapetoside B (-)-Borapetoside B	Structural Classification Terpenoids Source classification Diterpenoids Plants Tinospora crispa (L.) Hook. f. et Thoms Menispermaceae	Others
Borapetoside B ((-)-Borapetoside B) is a Diterpenoids product that can be isolated from the herbs of Caesalpinia minax HANCE. .

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Caesalpinia

Inhibitors & Agonists

Fluorescent Dye

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Natural
Products