CXCL13

By Targets:	ATP Citrate Lyase (1) CXCR (1) Small Interfering RNA (siRNA) (3) TNF Receptor (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99459

Baminercept 1 Publications Verification BG 9924; TT-47	TNF Receptor	Inflammation/Immunology
Baminercept (BG 9924) is an anti-lymphotoxin β receptor (LTβR) IgG fusion protein (LTβR-Ig). Baminercept selectively binds to the LTβR ligand LTα/β heterotrimer and LIGHT, block the LTβR signaling pathway, and inhibits the expression of chemokines such as CXCL13. Baminercept also regulates peripheral blood B cell and T cell subsets, reduces the transcription of IFN-induced genes. Thereby, Baminercept inhibits the formation of high endothelial venules and reticular structures in lymphoid tissues, and affects immune cell migration. Baminercept can be used for the study of autoimmune diseases such as primary Sjogren's syndrome (pSS) and rheumatoid arthritis (RA) .

HY-RS03387

CXCL13 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CXCL13 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CXCL13 Human Pre-designed siRNA Set A CXCL13 Human Pre-designed siRNA Set A

HY-RS16602

Cxcl13 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cxcl13 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcl13 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cxcl13 Mouse Pre-designed siRNA Set A Cxcl13 Mouse Pre-designed siRNA Set A

HY-RS23036

Cxcl13 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cxcl13 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcl13 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cxcl13 Rat Pre-designed siRNA Set A Cxcl13 Rat Pre-designed siRNA Set A

HY-P991567

VX5 VX5/5261	CXCR	Inflammation/Immunology Cancer
VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting *BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration (EC₅₀*s for 105 and 253 nM for human tonsillar and pre-B-697-hCXCR5 cells, respectively). VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .

HY-175606

EVT0185	ATP Citrate Lyase	Cancer
EVT0185 is an orally active ATP citrate lyase (ACLY) inhibitor. EVT0185 is converted to a CoA thioester in the liver by SLC27A2 and interacts with the CoA-binding site of ACLY. EVT0185-CoA inhibits ACLY activity with an IC₅₀ of 2.5 μM. EVT0185 can phenocopy the immune and antitumour effects of genetic ACLY deletion. EVT0185 can increases tumour-infiltrating B cells and chemokine CXCL13 levels. EVT0185 can be used for the research of cancer, such as hepatocellular carcinoma (HCC) .

Cat. No.	Product Name	Target	Research Area

HY-P99459

Baminercept 1 Publications Verification BG 9924; TT-47	TNF Receptor	Inflammation/Immunology
Baminercept (BG 9924) is an anti-lymphotoxin β receptor (LTβR) IgG fusion protein (LTβR-Ig). Baminercept selectively binds to the LTβR ligand LTα/β heterotrimer and LIGHT, block the LTβR signaling pathway, and inhibits the expression of chemokines such as CXCL13. Baminercept also regulates peripheral blood B cell and T cell subsets, reduces the transcription of IFN-induced genes. Thereby, Baminercept inhibits the formation of high endothelial venules and reticular structures in lymphoid tissues, and affects immune cell migration. Baminercept can be used for the study of autoimmune diseases such as primary Sjogren's syndrome (pSS) and rheumatoid arthritis (RA) .

HY-P991567

VX5 VX5/5261	CXCR	Inflammation/Immunology Cancer
VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting *BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration (EC₅₀*s for 105 and 253 nM for human tonsillar and pre-B-697-hCXCR5 cells, respectively). VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .

Species:	Human (3) Rat (1) Mouse (2) Cynomolgus (1) Pig (1)
Tag:	His (5) Tag Free (1) GST (1) Fc (1)
Source:	HEK293 (2) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P7131

	*BCA-1/CXCL13* Protein, Human** 3 Publications Verification rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Human	E. coli
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Human is produced in E. coli, and consists of 87 amino acids (V23-P109).

HY-P76164

	*BCA-1/CXCL13* Protein, Cynomolgus (His)** C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Cynomolgus	E. coli
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Cynomolgus (His) is produced in E. coli with a N-Terminal His-tag.

HY-P704362

	*BCA-1/CXCL13* Protein, Human (His)** BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Human	E. coli
	The BCA-1/CXCL13 protein selectively attracts B lymphocytes without affecting T lymphocytes, monocytes, or neutrophils. Unlike other chemokines, it does not induce calcium release from B lymphocytes. BCA-1/CXCL13 Protein, Human (His) is the recombinant human-derived BCA-1/CXCL13 protein, expressed by E. coli, with N-His labeled tag.

HY-P700547

	*BCA-1/CXCL13* Protein, Rat (His-GST)** rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Rat	E. coli
	The BCA-1/CXCL13 protein is a member of the intercrine α family and is critical for chemokines involved in intercellular communication and immune responses. As part of this family, BCA-1/CXCL13 may play a key role in regulating inflammatory processes and influencing cellular interactions. BCA-1/CXCL13 Protein, Rat (His-GST) is the recombinant rat-derived BCA-1/CXCL13 protein, expressed by E. coli , with N-GST, N-6*His labeled tag.

HY-P700044AF

	*Animal-Free BCA-1/CXCL13* Protein, Human (His)** BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Human	E. coli
	The BCA-1/CXCL13 protein selectively attracts B lymphocytes without affecting T lymphocytes, monocytes, or neutrophils. Unlike other chemokines, it does not induce calcium release from B lymphocytes. Animal-Free BCA-1/CXCL13 Protein, Human (His) is the recombinant human-derived animal-FreeBCA-1/CXCL13 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P77911

	*BCA-1/CXCL13* Protein, Mouse (HEK293, His)** 1 Publications Verification ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13	Mouse	HEK293
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Mouse (HEK293, His) is produced in HEK293 cells with a N-Terminal His-tag. It consists of 88 amino acids (I22-A109).

HY-P77912

	*BCA-1/CXCL13* Protein, Mouse (HEK293, Fc)** 1 Publications Verification ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13	Mouse	HEK293
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a N-Terminal Fc-tag. It consists of 88 amino acids (I22-A109).

HY-P700234AF

	*Animal-Free CXCL13* Protein, Pig (His)** C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Pig	E. coli
	The CXCL13 protein is a member of the intercrine α family and is critical for chemokines involved in intercellular communication and immune responses. In this family, CXCL13 may play a key role in regulating inflammatory processes and influencing cellular interactions. Animal-Free CXCL13 Protein, Pig (His) is the recombinant pig-derived animal-FreeCXCL13 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

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HY-P87311

	CXCL13 Antibody (YA6994) ANGIE antibody; ANGIE2 antibody; B cell attracting chemokine 1 antibody; B cell-attracting chemokine 1 antibody; B lymphocyte chemoattractant antibody; B-cell chemoattractant antibody; B-cell-attracting chemokine 1 antibody; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1) antibody; BCA-1 antibody; BCA1 antibody	WB, ICC/IF, IHC-P	Human
	CXCL13 Antibody (YA6994) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CXCL13.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS03387

CXCL13 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CXCL13 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS16602

Cxcl13 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cxcl13 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcl13 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23036

Cxcl13 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Cxcl13 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcl13 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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