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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

CRBN ligand-Linker Conjugate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	E3 Ligase Ligand-Linker Conjugates (84) Target Protein Ligand-Linker Conjugates (8) Akt (1) Apoptosis (8) Autophagy (6) Btk (2) c-Myc (1) CDK (1) E1/E2/E3 Enzyme (1) Epigenetic Reader Domain (1) ERK (1) Estrogen Receptor/ERR (1) FGFR (1) FLT3 (1) Fluorescent Dye (1) HDAC (1) HSP (1) Ligands for E3 Ligase (1) MAP4K (1) Molecular Glues (1) PI3K (1) PROTACs (11) STAT (1)
By Research Areas:	Cancer (92) Infection (1) Inflammation/Immunology (4)
Click Chemistry:	Azide (6)

105

Inhibitors & Agonists

Click Chemistry

Targets Recommended: Target Protein Ligand-Linker Conjugates E3 Ligase Ligand-Linker Conjugates ADC Linker PROTAC-Linker Conjugates for PAC Drug-Linker Conjugates for ADC PD-1/PD-L1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131875

Pomalidomide 4'-alkylC3-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-alkylC3-acid is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .

HY-160241

Lenalidomide-C5-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide-C5-acid is the Lenalidomide-based E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Lenalidomide-C5-acid can be used to synthesize PROTACs .

HY-175545

CRBN ligand-Linker Conjugate 1	E3 Ligase Ligand-Linker Conjugates	Cancer
CRBN ligand-Linker Conjugate 1 is a CRBN ligand-linker conjugate that can be used for synthesis of TQ-3959 (HY-175541) .

HY-139332

Pomalidomide 4'-PEG6-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .

HY-174797

Dione-piperidine-indazol-piperazin-cyclohexyl-NH2	E3 Ligase Ligand-Linker Conjugates	Others
Dione-piperidine-indazol-piperazin-cyclohexyl-NH2 is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand (HY-W883326) and linker. Dione-piperidine-indazol-piperazin-cyclohexyl-NH2 can be used for synthesis of PROTAC MD-4251 (HY-174458) .

HY-174880

CRBN ligand-8-O-C6-NH2	E3 Ligase Ligand-Linker Conjugates	Others
CRBN ligand-8-O-C6-NH2 is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand (HY-150831) and a linker. CRBN ligand-8-O-C6-NH2 can be used for synthesis of PROTAC ERα Degrader-11 (HY-174870) .

HY-176227

Thalidomide-piperidine-azetidine-Br	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-piperidine-azetidine-Br is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based CRBN ligand (HY-41547) and linker (HY-176226). Thalidomide-piperidine-azetidine-Br can be used for synthesis of BY13 (HY-176225) .

HY-176430

Lenalidomide-amide-pimelic acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide-amide-pimelic acid is an E3 ligase ligand-linker conjugate that incorporates the Lenalidomide (HY-A0003) based CRBN ligand and Linker (HY-Y1139). Lenalidomide-amide-pimelic acid can be used for synthesis of PROTAC MNK1 degrader-1 (HY-176428) .

HY-W1120221

Lenalidomide-C3-NH2	E3 Ligase Ligand-Linker Conjugates	Others
Lenalidomide-C3-NH2 is an E3 ligase ligand-linker conjugate that incorporates the Lenalidomide (HY-A0003) based CRBN ligand (HY-43722) and linker. Lenalidomide-C3-NH2 can be used for synthesis of PROTAC BET degrader-2 (HY-114228) .

HY-174813

Pomalidomide-PEG3-Cys	E3 Ligase Ligand-Linker Conjugates	Others
Pomalidomide-PEG3-Cys is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand Pomalidomide (HY-10984) and 3-unit PEG linker. Pomalidomide-PEG3-Cys can be used for synthesis of PROTAC BRD4 Degrader-33 (HY-174811) .

HY-174087

Thalidomide-4-OH-C11-OH	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-4-OH-C11-OH is an E3 Ligase Ligand-Linker Conjugate, which is composed of Thalidomide-4-OH (HY-103596) and the corresponding Linker. Thalidomide-4-OH-C11-OH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules, such as PROTAC GPX4 degrader-4 (HY-174086) .

HY-176181

Thalidomide-4-PEG4-OTs	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology
Thalidomide-4-OH-PEG4-OTs is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based CRBN ligand (HY-103596) and 4-unit PEG linker (HY-176182). Thalidomide-4-OH-PEG4-OTs can be used for synthesis of PROTAC STING degrader-4 (HY-176180) .

HY-174869

5-Aminothalidomide-NH-C7-NH2	E3 Ligase Ligand-Linker Conjugates	Others
5-Aminothalidomide-NH-C7-NH2 is an E3 ligase ligand-linker conjugate that incorporates the 5-Aminothalidomide (HY-W023573) based CRBN ligand (HY-103596) and linker. 5-Aminothalidomide-NH-C7-NH2 can be used for synthesis of PROTAC BT-O2C (HY-174866) .

HY-176425

E3 Ligase Ligand-linker Conjugate 186	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology
E3 Ligase Ligand-linker Conjugate 186 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 186 can be used to synthesize PROTAC SJ10542 (HY-145696) .

HY-172949

E3 Ligase Ligand-linker Conjugate 187	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 187 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 187 can be used to synthesize PROTAC SD-2301 (HY-172946) .

HY-172593

E3 Ligase Ligand-linker Conjugate 182	E3 Ligase Ligand-Linker Conjugates
E3 Ligase Ligand-linker Conjugate 182 is a E3 Ligase Ligand-Linker Conjugates. E3 Ligase Ligand-linker Conjugate 182 consists of a **CRBN ligand** and a PROTAC linker. E3 Ligase Ligand-linker Conjugate 182 can be used to design PROTACs (such as LZ-07 (HY-172590)) .

HY-170673

E3 Ligase Ligand-linker Conjugate 156	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 156 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 156 can be used to synthesize PROTAC XPO1 degrader-1 (HY-170669) .

HY-174796

E3 Ligase Ligand-linker Conjugate 195	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology
E3 Ligase Ligand-linker Conjugate 195 is a conjugate of the CRBN ligand (HY-174470) and the linker. E3 Ligase Ligand-linker Conjugate 195 can be used for synthesis of PROTACs such as APH02174 (HY-174455) .

HY-163922

CRBN ligand-1-piperidine-Me	E3 Ligase Ligand-Linker Conjugates	Cancer
CRBN ligand-1-piperidine-Me is an E3 ligase ligand-linker conjugate.

HY-44148

FAK ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates	Cancer
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation .

HY-176125

E3 Ligase Ligand-linker Conjugate 184	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 184 is a E3 Ligase Ligand-Linker Conjugates, consisting of CDK2 ligand-2 (HY-176124) and the corresponding Linker. E3 Ligase Ligand-linker Conjugate 184 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete CDK2 degrader 2 (HY-163815) .

HY-157756

E3 Ligase Ligand-linker Conjugate 104	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 104 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 104 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162197

E3 ligase Ligand-Linker Conjugate 41	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 41 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 41 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157600

E3 ligase Ligand-Linker Conjugate 66	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 66 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 66 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157747

E3 Ligase Ligand-linker Conjugate 99	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 99 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 99 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157748

E3 Ligase Ligand-linker Conjugate 100	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 100 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 100 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162180

E3 Ligase Ligand-linker Conjugate 2	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 2 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 2 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162203

E3 Ligase Ligand-linker Conjugate 51	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 51 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 51 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162190

E3 Ligase Ligand-linker Conjugate 17	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 17 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 17 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162192

E3 Ligase Ligand-linker Conjugate 20	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 20 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 20 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162206

E3 Ligase Ligand-linker Conjugate 58	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 58 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 58 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162184

E3 ligase Ligand-Linker Conjugate 11	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 11 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 11 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157761

E3 Ligase Ligand-linker Conjugate 106	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 106 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 106 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157588

(S)-Thalidomide-Piperazine-CH2-Pyrrolidine-C2-OH	Ligands for E3 Ligase Autophagy	Cancer
E3 ligase Ligand-Linker Conjugate 30 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 30 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162200

E3 Ligase Ligand-linker Conjugate 47	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 47 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 47 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162198

E3 ligase Ligand-Linker Conjugate 43	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 43 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 43 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162185

E3 Ligase Ligand-linker Conjugate 12	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 12 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 12 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162183

E3 Ligase Ligand-linker Conjugate 9	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 9 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 9 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162204

E3 Ligase Ligand-linker Conjugate 54	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 54 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 54 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157637

E3 Ligase Ligand-linker Conjugate 94	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 94 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 94 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162195

E3 ligase Ligand-Linker Conjugate 34	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 34 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 34 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157636

E3 Ligase Ligand-linker Conjugate 93	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 93 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 93 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162205

E3 Ligase Ligand-linker Conjugate 55	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 55 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 55 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162199

E3 Ligase Ligand-linker Conjugate 45	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 45 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 45 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157587

E3 ligase Ligand-Linker Conjugate 29	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 29 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 29 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157599

E3 ligase Ligand-Linker Conjugate 65	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 65 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 65 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157635

E3 Ligase Ligand-linker Conjugate 92	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 92 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 92 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162189

E3 Ligase Ligand-linker Conjugate 16	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 16 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 16 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-162187

E3 Ligase Ligand-linker Conjugate 14	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 14 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 Ligase Ligand-linker* Conjugate 14 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-157595

E3 ligase Ligand-Linker Conjugate 38	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 ligase Ligand-Linker Conjugate 38 is a **conjugate of E3 ligase ligand and linker*, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker* Conjugate 38 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

Cat. No.	Product Name		Classification

HY-139332

Pomalidomide 4'-PEG6-azide		Azide
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .

HY-139341

Pomalidomide 4'-alkylC3-azide		Azide
Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC .

HY-139343

Pomalidomide 4'-alkylC2-azide		Azide
Pomalidomide 4'-alkylC2-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC2-azide can be used in the synthesis of PROTAC .

HY-157511

Thalidomide-O-C5-azide		Azide
Thalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .

HY-157510

Thalidomide-O-C3-azide		Azide
Thalidomide-O-C3-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C3-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C3-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .

HY-157515

Thalidomide 4'-ether-PEG2-azide		Azide
Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .

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