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CHMFL-KIT-031

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122849
    CHMFL-KIT-031

    		c-Kit Cancer
    CHMFL-KIT-031 is a highly selective KIT V559D inhibitor, with an IC50 of 28 nM. CHMFL-KIT-031 potently affects KIT V559D mutant’s phosphorylation at Y703/719/823 sites. CHMFL-KIT-031 inhibits the tumor growth in BaF3-TEL-KIT-V559D cell inoculated mouse model .
    CHMFL-KIT-031

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