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CD23

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin-converting Enzyme (ACE) (1) EGFR (1) ERK (1) Interleukin Related (1) MMP (1) SARS-CoV (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (3)

2

Inhibitors & Agonists

2

Inhibitory Antibodies

4

Recombinant Proteins

2

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

JG26 1 Publications Verification	Angiotensin-converting Enzyme (ACE) MMP EGFR ERK SARS-CoV	Infection Cardiovascular Disease Cancer
JG26 is an ADAM inhibitor with IC₅₀ values of 12 nM, 1.9 nM, and 150 nM for ADAM8, ADAM17, and ADAM10, respectively. JG26 inhibits MMP-12 with an IC₅₀ value of 9.4 nM. JG26 inhibits AngII (HY-13948)-induced EGFR transactivation and ERK activation. JG26 increases the expression of ACE2, inhibits the cleavage of *CD23, reduces the infection of SARS-CoV-2*. JG26 inhibits colorectal cancer metastasis. JG26 can be used for research on Hodgkin lymphoma and vascular diseases .

AVP-13358	Interleukin Related	Inflammation/Immunology
AVP-13358 is an orally active IgE inhibitor that effectively suppresses immunoglobulin E (IgE)-mediated immune responses, with IC₅₀ values of 8 and 3 nM for IgE inhibition in vivo and in vitro in BALB/c mice, respectively. AVP-13358 acts directly on T cells, inhibiting the production and release of IL-4, IL-5, and IL-13. It also targets other markers critical for the development of allergic responses, including the B cell IgE receptor (CD23) in human monocytes and the *CD23* and IL-4 receptors in mouse B cells. AVP-13358 can be used in research related to anti-allergic responses .

Cat. No.	Product Name	Target	Research Area

Lumiliximab Gomiliximab; IDEC-152; ST-152	Inhibitory Antibodies	Inflammation/Immunology Cancer
Lumiliximab (Anti-CD23 Recombinant Antibody) is an anti-CD23 monoclonal antibody that inhibits allergen-induced responses .

Ligelizumab 1 Publications Verification QGE 031; Anti-IGHE Recombinant Antibody	Inhibitory Antibodies	Inflammation/Immunology
Ligelizumab (QGE 031) is a humanized high-affinity monoclonal anti-IgE antibody. Ligelizumab can be used for the research of chronic spontaneous urticarial .

Species:	Human (2) Rat (1) Mouse (1)
Tag:	His (3) Avi (1) Fc (1)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source

	CD23/Fc epsilon RII Protein, Human (HEK293, His) Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A; CLEC4J; FCE2; IGEBF	Human	HEK293
	CD23 or Fc epsilon receptor II (Fc epsilon RII) is a low-affinity receptor for immunoglobulin E (IgE) and complements receptor 2 (CR2/CD21). CD23 is present on B cells, regulates IgE production and B cell differentiation, and aids in IgE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Human (HEK293, His) is the recombinant human-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-8*His labeled tag.

	CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A	Rat	HEK293
	CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E (IgE) and complement receptor 2 (CR2/CD21). CD23 regulates IgE production and B-cell differentiation, aiding in IGE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-hFc labeled tag.

	CD23/Fc epsilon RII Protein, Mouse (HEK293, His) Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A	Mouse	HEK293
	CD23/Fc epsilon RII Protein, a low-affinity receptor for IgE and CR2/CD21, regulates IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway. CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding. CD23/Fc epsilon RII Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-His labeled tag.

	CD23/Fc epsilon RII Protein, Human (Biotinylated, HEK293, His, Avi) BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF; FCER2; FcεRII; Fcr; Fcgr; Fc receptor; CLEC-6; CLECSF8; MCL; MGC40078; MPCL; Fcer2a; Ly-42	Human	HEK293

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	CD23 Antibody (YA1296) BLAST-2, CD23A, CLEC4J, FCE2, IGEBF	IHC-P, ICC/IF, FC	Human
	CD23 Antibody (YA1296) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1296), targeting CD23. CD23 Antibody (YA1296) can be used for IHC-P, ICC/IF, FC experiment in human background.

	CD23 Antibody (YA4669) Blast 2 antibody; BLAST-2 antibody; Blast2 antibody; C type lectin domain family 4 member J antibody; C-type lectin domain family 4 antibody; C-type lectin domain family 4 member J antibody; C-type lectin domain family 4; member J antibody; CD 23 antibody; CD 23A antibody; CD23 antibody; CD23 antigen antibody; CD23A antibody; CLEC 4J antibody; CLEC4J antibody; Fc epsilon receptor II antibody; Fc epsilon RII antibody; Fc fragment of IgE antibody; Fc fragment of IgE low affinity II receptor for antibody; Fc fragment of IgE receptor II antibody; Fc fragment of IgE; low affinity II; receptor for; CD23; antibody; Fc of IgE antibody; Fc of IgE; low affinity II; receptor for; CD23; antibody; Fc receptor IgE low affinity II alpha polypeptide antibody; Fc receptor; IgE; low affinity II; alpha polypeptide; isoform CRA_a antibody; Fc-epsilon-RII antibody; FCE 2 antibody; FCE2 antibody; FCER 2 antibody; Fcer2 antibody; FCER2_HUMAN antibody; FCER2A antibody; FceRII antibody; IgE binding factor antibody; IgE receptor lymphocyte antibody; IgE-binding factor antibody; IGEBF antibody; Immunoglobulin E binding factor antibody; Immunoglobulin E receptor antibody; Immunoglobulin E receptor; low affinity II antibody; Immunoglobulin E-binding factor antibody; Immunoglobulin epsilon chain antibody; LEUKOCYTE ANTIGEN CD23 antibody; Low Affinity IgE Receptor antibody; Low affinity immunoglobulin epsilon Fc receptor antibody; Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody; Low affinity immunoglobulin epsilon Fc receptor soluble form antibody; Ly-42 antibody; Ly42 antibody; Lymphocyte antigen CD23 antibody; Lymphocyte IgE receptor antibody; MGC93219 antibody; CD23 nanobody	ELISA, FC	Human

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