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Results for "

BMF

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Peptides

1

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-150105
    Icovamenib

    BMF-219; Menin-MLL inhibitor 21

    		 Epigenetic Reader Domain Metabolic Disease Inflammation/Immunology Cancer
    Icovamenib (BMF-219) is a selective, orally active, irreversible Menin inhibitor. Icovamenib forms a stable and irreversible covalent bond with Menin. Icovamenib promotes selective and controlled proliferation of beta cells and improvement of beta cell function in ex vivo human islet cultures. Icovamenib enhances glycemic control in animal diabetic models. Icovamenib induces a dose-dependent enhancement in insulin secretion potentiated by the GLP-1 RA. Icovamenib can be used for the study of multiple hematologic malignancies, solid tumors, and diabetes mellitus, such as diffuse large B-cell lymphoma (DLBCL), multiple myeloma (MM) and chronic lymphocytic leukemia and type 2 diabetes .
    Icovamenib
  • HY-50868
    Bafetinib
    10+ Cited Publications

    INNO-406; NS-187

    		 Bcr-Abl Src Apoptosis Cancer
    Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph + leukemia cells. Bafetinib has antitumor activity .
    Bafetinib
  • HY-P1733
    BMf-BH3

    BMF-Y

    		 Apoptosis Cancer
    BMf-BH3 (BMF-Y) belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death .
    BMf-BH3
  • HY-RS18018
    Bmf Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Bmf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bmf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Bmf Mouse Pre-designed siRNA Set A
    Bmf Mouse Pre-designed siRNA Set A
  • HY-RS24491
    Bmf Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Bmf Rat Pre-designed siRNA Set A contains three designed siRNAs for Bmf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Bmf Rat Pre-designed siRNA Set A
    Bmf Rat Pre-designed siRNA Set A
  • HY-RS01531
    BMF Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BMF Human Pre-designed siRNA Set A contains three designed siRNAs for BMF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BMF Human Pre-designed siRNA Set A
    BMF Human Pre-designed siRNA Set A
  • HY-50868R
    Bafetinib (Standard)

    		Bcr-Abl Src Apoptosis Cancer
    Bafetinib (Standard) is the analytical standard of Bafetinib. This product is intended for research and analytical applications. Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity .
    Bafetinib (Standard)

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