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Results for "

BFCs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bcl-2 Family (2) Biochemical Assay Reagents (47) Cytochrome P450 (1) Fc Receptor (FcR) (1) ICMT (1) Integrin (1) Isotope-Labeled Compounds (1) Radionuclide-Drug Conjugates (RDCs) (13)
By Research Areas:	Cancer (8)
Click Chemistry:	DBCO (1) Azide (2) Alkynes (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W283556

DO2A-tert-butyl ester	Biochemical Assay Reagents	Cancer
DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers .

HY-161276

BFC1108	Apoptosis Bcl-2 Family	Cancer
BFC1108 is a small molecule Bcl-2 functional converter. BFC1108 induces a conformational change in Bcl-2, resulting in the exposure of its BH3 domain both in vitro and in vivo. BFC1108 effectively induces apoptosis in Bcl-2 expressing cancers. .

HY-W088413

DOTA-amide	Biochemical Assay Reagents	Others
DOTA-amideis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-amide can be used for conjugation of peptides and radionuclides.

HY-W678394

DOTA-Thiol	Biochemical Assay Reagents	Others
DOTA-Thiolis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-Thiol can be used for conjugation of peptides and radionuclides.

HY-158067

Deferoxamine-DBCO DFO-DBCO	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
Deferoxamine-DBCOis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DFO derivative used for tumor pre-targeting. Deferoxamine-DBCO can be used for conjugation of peptides and radionuclides.

HY-W782078

Butyne-DOTA	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
Butyne-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA can be used for conjugation of peptides and radionuclides.

HY-W267897

7-Benzyloxy-4-(trifluoromethyl)coumarin 7-BFC	Cytochrome P450	Others
7-Benzyloxy-4-(trifluoromethyl)coumarin (7-BFC) is a coumarin fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl)coumarin is a substrate for cDNA-expressed CYP1A2 and CYP3A4 and is metabolized to 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl)coumarin is used for rapid CYP isoform metabolism and inhibition screening studies .

HY-138134

NOTP	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NOTPis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTP can be used for conjugation of peptides and radionuclides.

HY-138269A

Barzuxetan hydrochloride CHX-A''-DTPA-NCS hydrochloride	Biochemical Assay Reagents	Others
Barzuxetan (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. Barzuxetan (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-134418A

NOTA trihydrochloride	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NOTA (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTA (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-158072

DOTAM-NHS-ester	Biochemical Assay Reagents	Others
DOTAM-NHS-esteris a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester can be used for conjugation of peptides and radionuclides.

HY-W717743

DOTAM-mono-acid	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
DOTAM-mono-acidis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-mono-acid can be used for conjugation of peptides and radionuclides.

HY-W717830

CB-Cyclam	Biochemical Assay Reagents	Others
CB-Cyclamis a bifunctional chelator (Bifunctional Chelator; *BFC*), which is a main chain Cyclen derivative of the macrocyclic ligand tetradecane. CB-Cyclam can be used for conjugation of peptides and radionuclides.

HY-W717782

Bz-DTPA hydrochloride	Biochemical Assay Reagents	Others
Bz-DTPA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. Bz-DTPA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W726767

DO2A	Biochemical Assay Reagents	Others
DO2Ais a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO2A can be used for conjugation of peptides and radionuclides.

HY-161577

BFC1103	Bcl-2 Family	Cancer
BFC1103 is a small-molecule compound whose primary mechanism of action involves interaction with a specific domain of Bcl-2, particularly its loop domain. This interaction induces a conformational change in Bcl-2, exposing its BH3 (Bcl-2 homology 3) domain, thereby switching Bcl-2's function from anti-apoptotic to pro-apoptotic. The cell death induced by BFC1103 is dependent on the presence of Bax or Bak, both of which are key proteins involved in the intrinsic apoptotic pathway mediated by mitochondria. BFC1103 has successfully inhibited lung metastasis of triple-negative breast cancer in mouse models. It can be utilized in studying the roles of Bcl-2 family proteins in cancer development and how they impact the survival and proliferation of cancer cells .

HY-W250844A

DO3A trisodium	Biochemical Assay Reagents	Others
DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.

HY-W087027A

Maleimide-NOTA TFA	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
Maleimide-NOTA (TFA)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. Maleimide-NOTA (TFA) can be used for conjugation of peptides and radionuclides.

HY-158077

(R)-tetraMe-Tetraxetan (R)-tetraMe-DOTA	Biochemical Assay Reagents	Others
(R)-tetraMe-Tetraxetanis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. (R)-tetraMe-Tetraxetan can be used for conjugation of peptides and radionuclides.

HY-W539916

Azido-mono-amide-DOTA	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
Azido-mono-amide-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Azido-mono-amide-DOTA can be used for conjugation of peptides and radionuclides.

HY-W717779

4-Aminobutyl-DOTA	Biochemical Assay Reagents	Others
4-Aminobutyl-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. 4-Aminobutyl-DOTA can be used for conjugation of peptides and radionuclides.

HY-158071

p-SCN-Bn-HEHA hydrochloride	Biochemical Assay Reagents	Others
p-SCN-Bn-HEHA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-SCN-Bn-HEHA (hydrochloride) can be used for drug conjugation.

HY-128890A

DOTA-NHS-ester hexafluorophosphate TFA	Biochemical Assay Reagents	Others
DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.

HY-A0074

DTPA-tetra (t-Bu ester) tetra-tBu-DTPA	Biochemical Assay Reagents	Others
DTPA-tetra (t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. DTPA-tetra (t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W782087A

p-SCN-Bn-PCTA hydrochloride	Biochemical Assay Reagents	Others
p-SCN-Bn-PCTA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-SCN-Bn-PCTA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W717781A

p-NH₂-Bn-DTPA hydrochloride	Biochemical Assay Reagents	Others
p-NH?-Bn-DTPA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-DTPA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W782088A

p-NH₂-Bn-PCTA hydrochloride	Biochemical Assay Reagents	Others
p-NH?-Bn-PCTA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-PCTA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W802013

DOTA-4AMP	Biochemical Assay Reagents	Others
DOTA-4AMPis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-4AMP can be used for conjugation of peptides and radionuclides.

HY-158068

Maleimido-mono-amide-DTPA TFA	Biochemical Assay Reagents	Others
Maleimido-mono-amide-DTPA (TFA)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. Maleimido-mono-amide-DTPA (TFA) can be used for conjugation of peptides and radionuclides.

HY-W749627

NO2A-Butyne	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne can be used for conjugation of peptides and radionuclides.

HY-W451440

Butyne-DOTA-tris(t-butyl ester)	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
Butyne-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.

HY-131673A

(S)-p-SCN-Bn-TCMC hydrochloride	Biochemical Assay Reagents	Others
(S)-p-SCN-Bn-TCMC (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-TCMC (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W717800A

NO2A-Azide trihydrochloride	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-156138A

CB-TE2A tetrahydrochloride	Biochemical Assay Reagents	Others
CB-TE2A (tetrahydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*), which is a TETA derivative of the macrocyclic ligand tetradecane backbone. CB-TE2A (tetrahydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W717833

NO2A-(t-Bu ester)	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NO2A-(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W782075

p-NO2-Bn-DOTA	Biochemical Assay Reagents	Others
p-NO2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NO2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

HY-48876

p-NH2-Bn-DOTA	Biochemical Assay Reagents	Others
p-NH2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

HY-W717742

p-NO2-Bn-Cyclen	Biochemical Assay Reagents	Others
p-NO2-Bn-Cyclenis a bifunctional chelator (Bifunctional Chelator; *BFC*), which is a derivative of the macrocyclic ligand dodecane backbone Cyclen. p-NO2-Bn-Cyclen can be used for conjugation of peptides and radionuclides.

HY-158069

p-NH₂-Bn-DTPA-penta (t-Bu ester)	Biochemical Assay Reagents	Others
p-NH?-Bn-DTPA-penta (t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-DTPA-penta (t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W460274

4-Aminobutyl-DOTA-tris(t-butyl ester)	Biochemical Assay Reagents	Others
4-Aminobutyl-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. 4-Aminobutyl-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.

HY-158066

p-NH2-Bn-NOTA hydrochloride hydrate	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
p-NH2-Bn-NOTA (hydrochloride hydrate)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. p-NH2-Bn-NOTA (hydrochloride hydrate) can be used for conjugation of peptides and radionuclides.

HY-W250929

Maleimido-mono-amide-DOTA-tris(t-Bu ester)	Biochemical Assay Reagents	Others
Maleimido-mono-amide-DOTA-tris(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Maleimido-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-148646A

p-NH2-CHX-A"-DTPA hydrochloride hydrate	Biochemical Assay Reagents	Others
p-NH2-CHX-A"-DTPA (hydrochloride hydrate)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH2-CHX-A"-DTPA (hydrochloride hydrate) can be used for conjugation of peptides and radionuclides.

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-W749603

Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)	Biochemical Assay Reagents	Others
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W749614

NO2A-Butyne-bis(t-Butyl ester)	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.

HY-W782081

p-SCN-Bn-oxo-DO3A	Biochemical Assay Reagents	Others
p-SCN-Bn-oxo-DO3Ais a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-SCN-Bn-oxo-DO3A can be used for conjugation of peptides and radionuclides.

HY-W088413A

DOTA-amide dihydrate	Biochemical Assay Reagents	Cancer
DOTA-amide (dihydrate) is a Bifunctional Chelators (BFCs). DOTA-amide (dihydrate) binds to the Affibody molecule ZHER2:S1. Its complex binds specifically to HER2 and can be used to detect bone metastases, which are common in prostate cancer .

HY-W717760

p-NH2-Bn-DOTA-tetra(t-Bu ester)	Biochemical Assay Reagents	Others
p-NH2-Bn-DOTA-tetra(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA-tetra(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-156038

(S)-p-SCN-Bn-DOTA	Biochemical Assay Reagents	Others
(S)-p-SCN-Bn-DOTA is a bifunctional chelator (BFC), a macrocyclic DOTA derivative for tumor pretargeting. (S)-p-SCN-Bn-DOTA can be used for the conjugation of peptides and radionuclides, such as as a linker for In-111 labeled radioimmunoconjugates (RICs) for single photon emission tomography (SPECT) and in vitro biodistribution studies .

Cat. No.	Product Name	Type

HY-W283556

DO2A-tert-butyl ester	Chelators
DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers .

HY-W088413

DOTA-amide	Chelators
DOTA-amideis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-amide can be used for conjugation of peptides and radionuclides.

HY-W678394

DOTA-Thiol	Chelators
DOTA-Thiolis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-Thiol can be used for conjugation of peptides and radionuclides.

HY-158067

Deferoxamine-DBCO DFO-DBCO	Chelators
Deferoxamine-DBCOis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DFO derivative used for tumor pre-targeting. Deferoxamine-DBCO can be used for conjugation of peptides and radionuclides.

HY-W782078

Butyne-DOTA	Chelators
Butyne-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA can be used for conjugation of peptides and radionuclides.

HY-W717743

DOTAM-mono-acid	Chelators
DOTAM-mono-acidis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-mono-acid can be used for conjugation of peptides and radionuclides.

HY-138134

NOTP	Chelators
NOTPis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTP can be used for conjugation of peptides and radionuclides.

HY-138269A

Barzuxetan hydrochloride CHX-A''-DTPA-NCS hydrochloride	Chelators
Barzuxetan (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. Barzuxetan (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-134418A

NOTA trihydrochloride	Chelators
NOTA (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTA (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-158072

DOTAM-NHS-ester	Chelators
DOTAM-NHS-esteris a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester can be used for conjugation of peptides and radionuclides.

HY-W717830

CB-Cyclam	Chelators
CB-Cyclamis a bifunctional chelator (Bifunctional Chelator; *BFC*), which is a main chain Cyclen derivative of the macrocyclic ligand tetradecane. CB-Cyclam can be used for conjugation of peptides and radionuclides.

HY-W717782

Bz-DTPA hydrochloride	Chelators
Bz-DTPA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. Bz-DTPA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W726767

DO2A	Chelators
DO2Ais a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO2A can be used for conjugation of peptides and radionuclides.

HY-W250844A

DO3A trisodium	Chelators
DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.

HY-W087027A

Maleimide-NOTA TFA	Chelators
Maleimide-NOTA (TFA)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. Maleimide-NOTA (TFA) can be used for conjugation of peptides and radionuclides.

HY-158077

(R)-tetraMe-Tetraxetan (R)-tetraMe-DOTA	Chelators
(R)-tetraMe-Tetraxetanis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. (R)-tetraMe-Tetraxetan can be used for conjugation of peptides and radionuclides.

HY-W539916

Azido-mono-amide-DOTA	Chelators
Azido-mono-amide-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Azido-mono-amide-DOTA can be used for conjugation of peptides and radionuclides.

HY-W717779

4-Aminobutyl-DOTA	Chelators
4-Aminobutyl-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. 4-Aminobutyl-DOTA can be used for conjugation of peptides and radionuclides.

HY-158071

p-SCN-Bn-HEHA hydrochloride	Chelators
p-SCN-Bn-HEHA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-SCN-Bn-HEHA (hydrochloride) can be used for drug conjugation.

HY-128890A

DOTA-NHS-ester hexafluorophosphate TFA	Chelators
DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.

HY-A0074

DTPA-tetra (t-Bu ester) tetra-tBu-DTPA	Chelators
DTPA-tetra (t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. DTPA-tetra (t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W782087A

p-SCN-Bn-PCTA hydrochloride	Chelators
p-SCN-Bn-PCTA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-SCN-Bn-PCTA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W717781A

p-NH₂-Bn-DTPA hydrochloride	Chelators
p-NH?-Bn-DTPA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-DTPA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W782088A

p-NH₂-Bn-PCTA hydrochloride	Chelators
p-NH?-Bn-PCTA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-PCTA (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W802013

DOTA-4AMP	Chelators
DOTA-4AMPis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-4AMP can be used for conjugation of peptides and radionuclides.

HY-158068

Maleimido-mono-amide-DTPA TFA	Chelators
Maleimido-mono-amide-DTPA (TFA)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. Maleimido-mono-amide-DTPA (TFA) can be used for conjugation of peptides and radionuclides.

HY-W749627

NO2A-Butyne	Chelators
NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne can be used for conjugation of peptides and radionuclides.

HY-W451440

Butyne-DOTA-tris(t-butyl ester)	Chelators
Butyne-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.

HY-131673A

(S)-p-SCN-Bn-TCMC hydrochloride	Chelators
(S)-p-SCN-Bn-TCMC (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-TCMC (hydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W717800A

NO2A-Azide trihydrochloride	Chelators
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-156138A

CB-TE2A tetrahydrochloride	Chelators
CB-TE2A (tetrahydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*), which is a TETA derivative of the macrocyclic ligand tetradecane backbone. CB-TE2A (tetrahydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W717833

NO2A-(t-Bu ester)	Chelators
NO2A-(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W782075

p-NO2-Bn-DOTA	Chelators
p-NO2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NO2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

HY-48876

p-NH2-Bn-DOTA	Chelators
p-NH2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

HY-W717742

p-NO2-Bn-Cyclen	Chelators
p-NO2-Bn-Cyclenis a bifunctional chelator (Bifunctional Chelator; *BFC*), which is a derivative of the macrocyclic ligand dodecane backbone Cyclen. p-NO2-Bn-Cyclen can be used for conjugation of peptides and radionuclides.

HY-158069

p-NH₂-Bn-DTPA-penta (t-Bu ester)	Chelators
p-NH?-Bn-DTPA-penta (t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-DTPA-penta (t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W460274

4-Aminobutyl-DOTA-tris(t-butyl ester)	Chelators
4-Aminobutyl-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. 4-Aminobutyl-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.

HY-158066

p-NH2-Bn-NOTA hydrochloride hydrate	Chelators
p-NH2-Bn-NOTA (hydrochloride hydrate)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. p-NH2-Bn-NOTA (hydrochloride hydrate) can be used for conjugation of peptides and radionuclides.

HY-W250929

Maleimido-mono-amide-DOTA-tris(t-Bu ester)	Chelators
Maleimido-mono-amide-DOTA-tris(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Maleimido-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-148646A

p-NH2-CHX-A"-DTPA hydrochloride hydrate	Chelators
p-NH2-CHX-A"-DTPA (hydrochloride hydrate)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH2-CHX-A"-DTPA (hydrochloride hydrate) can be used for conjugation of peptides and radionuclides.

HY-W749603

Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)	Chelators
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W749614

NO2A-Butyne-bis(t-Butyl ester)	Chelators
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.

HY-W782081

p-SCN-Bn-oxo-DO3A	Chelators
p-SCN-Bn-oxo-DO3Ais a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-SCN-Bn-oxo-DO3A can be used for conjugation of peptides and radionuclides.

HY-W088413A

DOTA-amide dihydrate	Chelators
DOTA-amide (dihydrate) is a Bifunctional Chelators (BFCs). DOTA-amide (dihydrate) binds to the Affibody molecule ZHER2:S1. Its complex binds specifically to HER2 and can be used to detect bone metastases, which are common in prostate cancer .

HY-W717760

p-NH2-Bn-DOTA-tetra(t-Bu ester)	Chelators
p-NH2-Bn-DOTA-tetra(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA-tetra(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-156038

(S)-p-SCN-Bn-DOTA	Chelators
(S)-p-SCN-Bn-DOTA is a bifunctional chelator (BFC), a macrocyclic DOTA derivative for tumor pretargeting. (S)-p-SCN-Bn-DOTA can be used for the conjugation of peptides and radionuclides, such as as a linker for In-111 labeled radioimmunoconjugates (RICs) for single photon emission tomography (SPECT) and in vitro biodistribution studies .

HY-W782080

p-NH2-Bn-oxo-DO3A	Chelators
p-NH2-Bn-oxo-DO3Ais a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-oxo-DO3A can be used for conjugation of peptides and radionuclides.

HY-100133A

DOTA-ADIBO TFA	Chelators
DOTA-ADIBO TFA is a DOTA-derived bifunctional chelator (BFC) that allows drug conjugation via an uncatalyzed, copper-free cycloaddition reaction. DOTA-ADIBO TFA enables the construction of fusion chelator systems that can be further used to synthesize radiotracers after Cu[64] modification. Positron emission tomography imaging of tumors expressing integrin αvβ6 .

Cat. No.	Product Name	Target	Research Area

HY-P991582

BI-1607	Fc Receptor (FcR)	Cancer
BI-1607 is a humanized monoclonal antibody targeting CD32b/FcγRIIB. BI-1607 has an antagonistic function capable of blocking the inhibitory function of FcγRIIB on immune effector cells. BI-1607 has a significant cytolytic activity against malignant B cells and antitumor activity against HER2-positive solid tumors including advanced gastric cancer (GC) with combination with Trastuzumab (HY-P9907) .

Cat. No.	Product Name		Classification

HY-158067

Deferoxamine-DBCO DFO-DBCO		DBCO
Deferoxamine-DBCOis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DFO derivative used for tumor pre-targeting. Deferoxamine-DBCO can be used for conjugation of peptides and radionuclides.

HY-W782078

Butyne-DOTA		Alkynes
Butyne-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA can be used for conjugation of peptides and radionuclides.

HY-W539916

Azido-mono-amide-DOTA		Azide
Azido-mono-amide-DOTAis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Azido-mono-amide-DOTA can be used for conjugation of peptides and radionuclides.

HY-W749627

NO2A-Butyne		Alkynes
NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne can be used for conjugation of peptides and radionuclides.

HY-W451440

Butyne-DOTA-tris(t-butyl ester)		Alkynes
Butyne-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.

HY-W717800A

NO2A-Azide trihydrochloride		Azide
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W749614

NO2A-Butyne-bis(t-Butyl ester)		Alkynes
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; *BFC*) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.

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