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  4. p-NH2-Bn-DOTA

p-NH2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

p-NH2-Bn-DOTA

p-NH2-Bn-DOTA Chemical Structure

CAS No. : 181065-46-3

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Based on 1 publication(s) in Google Scholar

p-NH2-Bn-DOTA Related Antibodies

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Description

p-NH2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

Molecular Weight

509.55

Formula

C23H35N5O8
CAS No.
Appearance

Solid

Color

off-white

SMILES

OC(CN(CCN(CCN(CCN(C1)CC(O)=O)CC(O)=O)CC(O)=O)[C@H]1CC2=CC=C(C=C2)N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (196.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9625 mL 9.8126 mL 19.6252 mL
5 mM 0.3925 mL 1.9625 mL 3.9250 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.9625 mL 9.8126 mL 19.6252 mL 49.0629 mL
5 mM 0.3925 mL 1.9625 mL 3.9250 mL 9.8126 mL
10 mM 0.1963 mL 0.9813 mL 1.9625 mL 4.9063 mL
15 mM 0.1308 mL 0.6542 mL 1.3083 mL 3.2709 mL
20 mM 0.0981 mL 0.4906 mL 0.9813 mL 2.4531 mL
25 mM 0.0785 mL 0.3925 mL 0.7850 mL 1.9625 mL
30 mM 0.0654 mL 0.3271 mL 0.6542 mL 1.6354 mL
40 mM 0.0491 mL 0.2453 mL 0.4906 mL 1.2266 mL
50 mM 0.0393 mL 0.1963 mL 0.3925 mL 0.9813 mL
60 mM 0.0327 mL 0.1635 mL 0.3271 mL 0.8177 mL
80 mM 0.0245 mL 0.1227 mL 0.2453 mL 0.6133 mL
100 mM 0.0196 mL 0.0981 mL 0.1963 mL 0.4906 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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p-NH2-Bn-DOTA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p-NH2-Bn-DOTA181065-46-3Biochemical Assay ReagentsInhibitorinhibitorinhibit

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