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Aspergillus flavus

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (4) Bacterial (3) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (2) Fungal (9) Neurokinin Receptor (1) Parasite (1) Reference Standards (3) SARS-CoV (2) Tyrosinase (2) α-synuclein (1)
By Research Areas:	Cancer (3) Infection (12) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (3)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116909

O-Methylsterigmatocystin	Drug Metabolite	Others
O-Methylsterigmatocystin is a metabolite in Aspergillus flavus and Aspergillus parasiticus .

HY-108416

5,7-Dihydroxy-4-methylphthalide	Drug Intermediate	Others
5,7-Dihydroxy-4-methylphthalide is a key intermediate in the synthesis of Mycophenolic acid and a secondary metabolite of Aspergillus flavus .

HY-N7312

Ditryptophenaline (-)-Ditryptophenaline	Neurokinin Receptor	Inflammation/Immunology
Ditryptophenaline ((-)-Ditryptophenaline) is the metabolites of Aspergillus flavus. Ditryptophenaline inhibits substance P receptor and has anti-inflammatory activity .

HY-19404

Embeconazole CS-758; R-120758	Fungal	Infection
Embeconazole (CS-758; R-120758) is an antifungal agent against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Aspergillus flavus, with MICs of 8, 16, 63 and 250 μM, respectively .

HY-N10080

Paspalinine	Others	Neurological Disease
Paspalinine is a tremorgenic metabolite that can be found in Aspergillus flavus .

HY-N14582

Glomosporin	Antibiotic Fungal	Infection
Glomosporin is a cyclic ester peptide antifungal antibiotic, and it has moderate anti-Aspergillus flavus (including Aspergillus Niger and Aspergillus Niger), yeast activity (MIC is 16 μg/mL) .

HY-N9713

Dihydroxyaflavinine	Others	Others
Dihydroxyaflavinine (Compound Ⅲ) is an indole metabolite extracted from Aspergillus flavus .

HY-N14509

Queenslandon	Fungal	Infection
Queenslandon has moderate anti-streptomyces, penicillium, Penicillium, Aspergillus fumigatus, aspergillus flavus and other fungal activities. And it has no effect on bacteria .

HY-N14187

Aspergillic acid	Antibiotic Bacterial	Infection
Aspergillic acid is an antibiotic found in Aspergillus flavus. Aspergillic acid has a broad spectrum of antibacterial activity .

HY-N7780

Aflatrem	Others	Neurological Disease
Aflatrem is a mycotoxin that can be isolated from Aspergillus flavus. Aflatrem has acute neurotoxic effects and can be ued in neurological disease .

HY-133709

β-Aflatrem	Parasite	Infection
β-Aflatrem is an insecticide metabolite from the sclerotium of Aspergillus flavus that exhibits significant activity against the corn borer H. zea .

HY-N8894

(-)-Isolariciresinol 9'-O-glucoside (-)-Isolariciresinol 3α-O-β-D-glucopyranoside	Others	Others
(-)-Isolariciresinol 9'-O-glucoside ((-)-Isolariciresinol 3α-O-β-D-glucopyranoside) is a Diterpenoids product that can be isolated from From Aspergillus flavus .

HY-N12056

Cyclo(L-leucyl-L-valyl)	Fungal	Infection
Cyclo(L-leucyl-L-valyl) inhibits Aflatoxin production by Aspergillus parasiticus.Cyclo(L-leucyl-L-valyl) inhibits transcription of the Aflatoxin-related genes aflR, hexB, pksL1, and dmtA. .

HY-N15309

Torvoside C Torvoside K	Fungal	Infection
Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal activity. The ZOIs and MIC values of Torvoside C against the tested fungi (Alternaria brassicicola, Alternaria geophila, Aspergillus flavus, etc.) range from 33.4% to 87.4% and 31.25 to 250 μg/mL, respectively. Additionally, it exhibits a dose-dependent inhibitory effect on the production of mycotoxins aflatoxin B1 and fumonisin B1, which are produced by A. flavus and F. verticillioides, respectively. Torvoside C can be used for research in the field of antifungal infection .

HY-147804

SARS-CoV-2 3CLpro-IN-3	SARS-CoV Bacterial Fungal	Infection
SARS-CoV-2 3CLpro-IN-3 (Compound 3d) is a SARS CoV-2 3CLpro inhibitor with antiviral, antibacterial and antifungal activities .

HY-B0856

Validamycin A 1 Publications Verification	Fungal Tyrosinase Antibiotic	Infection
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a K_i of 5.893 mM .

HY-B0856R

Validamycin A (Standard)	Reference Standards Fungal Tyrosinase Antibiotic	Infection
Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .

HY-Y0337A

L-Cysteine hydrochloride 5+ Cited Publications	Endogenous Metabolite	Metabolic Disease Cancer
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .

HY-Y0337AR

L-Cysteine hydrochloride (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].

HY-147805

SARS-CoV-2 3CLpro-IN-4	SARS-CoV Bacterial Fungal	Infection
SARS-CoV-2 3CLpro-IN-4 (Compound 5g) is a SARS CoV-2 3CLpro inhibitor with antiviral, antibacterial and antifungal activities .

HY-Y0790R

Cuminaldehyde (Standard) p-Isopropylbenzaldehyde (Standard)	α-synuclein Reference Standards	Infection Neurological Disease Inflammation/Immunology Cancer
Cuminaldehyde Standard is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC₅₀= 0.00085 mg/mL) and α-glucosidase (IC₅₀=0.5 mg/mL). Cuminaldehyde also inhibits the fibrillation of α-synuclein and prevents its aggregation Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases .

O-Methylsterigmatocystin	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite
O-Methylsterigmatocystin is a metabolite in Aspergillus flavus and Aspergillus parasiticus .

Ditryptophenaline (-)-Ditryptophenaline	Structural Classification Alkaloids Human Gut Microbiota Metabolites Microorganisms Other Alkaloids Source classification Endogenous metabolite	Neurokinin Receptor
Ditryptophenaline ((-)-Ditryptophenaline) is the metabolites of Aspergillus flavus. Ditryptophenaline inhibits substance P receptor and has anti-inflammatory activity .

Paspalinine	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	Others
Paspalinine is a tremorgenic metabolite that can be found in Aspergillus flavus .

Glomosporin	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic Fungal
Glomosporin is a cyclic ester peptide antifungal antibiotic, and it has moderate anti-Aspergillus flavus (including Aspergillus Niger and Aspergillus Niger), yeast activity (MIC is 16 μg/mL) .

Dihydroxyaflavinine	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	Others
Dihydroxyaflavinine (Compound Ⅲ) is an indole metabolite extracted from Aspergillus flavus .

Queenslandon	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Queenslandon has moderate anti-streptomyces, penicillium, Penicillium, Aspergillus fumigatus, aspergillus flavus and other fungal activities. And it has no effect on bacteria .

Aspergillic acid	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Aspergillic acid is an antibiotic found in Aspergillus flavus. Aspergillic acid has a broad spectrum of antibacterial activity .

Aflatrem	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Aflatrem is a mycotoxin that can be isolated from Aspergillus flavus. Aflatrem has acute neurotoxic effects and can be ued in neurological disease .

β-Aflatrem	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Parasite
β-Aflatrem is an insecticide metabolite from the sclerotium of Aspergillus flavus that exhibits significant activity against the corn borer H. zea .

(-)-Isolariciresinol 9'-O-glucoside (-)-Isolariciresinol 3α-O-β-D-glucopyranoside	Structural Classification Source classification Lignans Oplopanax horridus (Smith.) Miq. Phenylpropanoids Plants Araliaceae	Others
(-)-Isolariciresinol 9'-O-glucoside ((-)-Isolariciresinol 3α-O-β-D-glucopyranoside) is a Diterpenoids product that can be isolated from From Aspergillus flavus .

Cyclo(L-leucyl-L-valyl)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Fungal
Cyclo(L-leucyl-L-valyl) inhibits Aflatoxin production by Aspergillus parasiticus.Cyclo(L-leucyl-L-valyl) inhibits transcription of the Aflatoxin-related genes aflR, hexB, pksL1, and dmtA. .

Torvoside C Torvoside K	Structural Classification Polysaccharides Source classification Solanum torvum Swartz Solanaceae Plants Saccharides	Fungal
Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal activity. The ZOIs and MIC values of Torvoside C against the tested fungi (Alternaria brassicicola, Alternaria geophila, Aspergillus flavus, etc.) range from 33.4% to 87.4% and 31.25 to 250 μg/mL, respectively. Additionally, it exhibits a dose-dependent inhibitory effect on the production of mycotoxins aflatoxin B1 and fumonisin B1, which are produced by A. flavus and F. verticillioides, respectively. Torvoside C can be used for research in the field of antifungal infection .

Validamycin A 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Fungal Tyrosinase Antibiotic
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a K_i of 5.893 mM .

Validamycin A (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Fungal Tyrosinase Antibiotic
Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .

L-Cysteine hydrochloride 5+ Cited Publications	Structural Classification Classification of Application Fields Anti-aging Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .

L-Cysteine hydrochloride (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Reference Standards Endogenous Metabolite
L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].

Cuminaldehyde (Standard) p-Isopropylbenzaldehyde (Standard)	Structural Classification Ketones, Aldehydes, Acids Rudbeckia laciniata L. Source classification Umbelliferae Plants Endogenous metabolite	α-synuclein Reference Standards
Cuminaldehyde Standard is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC₅₀= 0.00085 mg/mL) and α-glucosidase (IC₅₀=0.5 mg/mL). Cuminaldehyde also inhibits the fibrillation of α-synuclein and prevents its aggregation Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases .

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Aspergillus flavus

Inhibitors & Agonists

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