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Aristolochic acid I (Standard)

" in MedChemExpress (MCE) Product Catalog:

3

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3

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0510R
    Aristolochic acid A (Standard)

    Aristolochic acid I (Standard); TR 1736 (Standard)

    		 Reference Standards NF-κB Cancer
    Aristolochic acid A (Standard) is the analytical standard of Aristolochic acid A. This product is intended for research and analytical applications. Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .
    Aristolochic acid A (Standard)
  • HY-N0511R
    Aristolochic acid B (Standard)

    Aristolochic acid II (Standard)

    		 Reference Standards DNA Alkylator/Crosslinker Cancer
    Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B (HY-N0511). This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .
    Aristolochic acid B (Standard)
  • HY-N2013R
    Aristolactam I (Standard)

    Aristololactam (Standard); Aristolactam (Standard)

    		 Reference Standards Caspase Apoptosis Inflammation/Immunology
    Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .
    Aristolactam I (Standard)

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